Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases

Kerr, William J. and Lindsay, David M. and Patel, Vipulkumar K. and Rajamanickam, Muralikrishnan (2015) Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases. Organic and Biomolecular Chemistry, 13 (40). pp. 10131-10135. ISSN 1477-0520

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      Abstract

      Efficient conversion of ketones into kinetic enol phosphates under mild and accessible conditions has been realised using the developed methods with di-tert-butylmagnesium and bismesitylmagnesium. Optimisation of the quench protocol resulted in high yields of enol phosphates from a range of cyclohexanones and aryl methyl ketones, with tolerance of a range of additional functional units.

      ORCID iDs

      Kerr, William J. ORCID logoORCID: https://orcid.org/0000-0002-1332-785X, Lindsay, David M. ORCID logoORCID: https://orcid.org/0000-0003-4498-5094, Patel, Vipulkumar K. and Rajamanickam, Muralikrishnan ORCID logoORCID: https://orcid.org/0000-0001-9836-5478;
      • Item type:Article
        ID code:54691
        Dates:
        Date
        Event
        21 September 2015
        Published
        16 September 2015
        Accepted
        Keywords:ketones, kinetic enol phosphates, cyclohexanones, Chemistry, Chemistry(all)
        Subjects:Science > Chemistry
        Department:Faculty of Science > Pure and Applied Chemistry
        Depositing user: Pure Administrator
        Date deposited:11 Dec 2015 01:13
        Last modified:24 Mar 2021 01:32
        Related URLs:
        URI:https://strathprints.strath.ac.uk/id/eprint/54691
      CORE (COnnecting REpositories)