Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases

Kerr, William J. and Lindsay, David M. and Patel, Vipulkumar K. and Rajamanickam, Muralikrishnan (2015) Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases. Organic and Biomolecular Chemistry, 13 (40). pp. 10131-10135. ISSN 1477-0520 (https://doi.org/10.1039/C5OB01849H)

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Abstract

Efficient conversion of ketones into kinetic enol phosphates under mild and accessible conditions has been realised using the developed methods with di-tert-butylmagnesium and bismesitylmagnesium. Optimisation of the quench protocol resulted in high yields of enol phosphates from a range of cyclohexanones and aryl methyl ketones, with tolerance of a range of additional functional units.

ORCID iDs

Kerr, William J. ORCID logoORCID: https://orcid.org/0000-0002-1332-785X, Lindsay, David M. ORCID logoORCID: https://orcid.org/0000-0003-4498-5094, Patel, Vipulkumar K. and Rajamanickam, Muralikrishnan ORCID logoORCID: https://orcid.org/0000-0001-9836-5478;
  • Item type:Article
    ID code:54691
    Dates:
    Date
    Event
    21 September 2015
    Published
    16 September 2015
    Accepted
    Keywords:ketones, kinetic enol phosphates, cyclohexanones, Chemistry, Chemistry(all)
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:11 Dec 2015 01:13
    Last modified:24 Mar 2022 01:46
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/54691
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