Flexible access to conformationally-locked bicyclic morpholines

Bogacki, Rachael and Gill, Duncan M. and Kerr, W. J. and Lamont, Scott and Parkinson, John A. and Paterson, Laura C. (2013) Flexible access to conformationally-locked bicyclic morpholines. Journal of the Chemical Society, Chemical Communications, 49 (79). pp. 8931-8933. ISSN 0022-4936

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    Abstract

    A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available key building blocks.