Are rate and selectivity correlated in iridium-catalysed hydrogen isotope exchange reactions?
Timofeeva, Daria S. and Lindsay, David M. and Kerr, William J. and Nelson, David J. (2021) Are rate and selectivity correlated in iridium-catalysed hydrogen isotope exchange reactions? Catalysis Science and Technology, 11 (16). pp. 5498-5504. ISSN 2044-4753 (https://doi.org/10.1039/D1CY00708D)
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Abstract
Herein we qualitatively examine the relationship between reaction rate and reaction selectivity in iridium-catalysed hydrogen isotope exchange (HIE) reactions directed by Lewis basic functional groups. We have recently developed a directing group scale that allows semi-quantitative predictions of Lewis base directed selectivity in HIE, formally ranking 'relative rates' determined from a structured set of competition experiments. Here, we show that selectivity and rate are in fact not correlated, but that different types of behaviour emerge in competition experiments and that the observed behaviour can be predicted from our established selectivity scale.
ORCID iDs
Timofeeva, Daria S., Lindsay, David M. ORCID: https://orcid.org/0000-0003-4498-5094, Kerr, William J. ORCID: https://orcid.org/0000-0002-1332-785X and Nelson, David J. ORCID: https://orcid.org/0000-0002-9461-5182;-
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Item type: Article ID code: 77094 Dates: DateEvent21 August 2021Published9 July 2021Published Online9 July 2021AcceptedSubjects: Science > Chemistry Department: Faculty of Science > Pure and Applied Chemistry Depositing user: Pure Administrator Date deposited: 14 Jul 2021 13:50 Last modified: 01 Sep 2024 01:30 URI: https://strathprints.strath.ac.uk/id/eprint/77094