3D printing MicroFactory for amorphous solid dispersion formulations
Prasad, Elke and Hueckman, Jill and Bordos, Ecaterina and Robertson, John and Halbert, Gavin W. (2024) 3D printing MicroFactory for amorphous solid dispersion formulations. In: CMAC Summer School 2024, 2023-07-10 - 2024-07-14.
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Abstract
This study utilised the HUB Additive-ManufacturingMicroFactory as an enabler for streamlined manufacture of Amorphous Solid Dispersion (ASD) formulation of the model compound Ritonavir with an immediate release polymer Soluplus® (BASF). The Digital Design and Manufacture of Amorphous Pharmaceuticals (DDMAP) research program identified Soluplus® as a superior polymer to form stable ASD formulation with Ritonavir. The drug release from 3D printed (3DP) Ritonavir ASD formulations with Soluplus® were compared to a commercial product (Norvir, 100mg, Abbvie Ltd).
ORCID iDs
Prasad, Elke ORCID: https://orcid.org/0000-0002-5412-9374, Hueckman, Jill, Bordos, Ecaterina, Robertson, John ORCID: https://orcid.org/0000-0002-2191-1319 and Halbert, Gavin W.;-
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Item type: Conference or Workshop Item(Poster) ID code: 90037 Dates: DateEvent14 July 2024PublishedSubjects: Medicine > Pharmacy and materia medica > Pharmaceutical technology
Technology > ManufacturesDepartment: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Technology and Innovation Centre > Continuous Manufacturing and Crystallisation (CMAC)Depositing user: Pure Administrator Date deposited: 25 Jul 2024 12:04 Last modified: 10 Oct 2024 00:36 Related URLs: URI: https://strathprints.strath.ac.uk/id/eprint/90037