Improving consistency for a Mefenamic acid immediate release formulation

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2020) Improving consistency for a Mefenamic acid immediate release formulation. In: CMAC Annual Open Day, 2020-10-21 - 2020-10-22, Virtual event.

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Abstract

Mefenamic acid (MFA) product performance is highly dependant on particle size and can lead to variable efficacy. In this study, a structured development program was applied, developing a crystalline solid dispersion (CSD) formulation, retaining API properties and improving performance consistency compared to a commercial product.