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2022

Chong, Magdalene and Brown, Cameron and Mustoe, Chantal and McGinty, John and Li, Wei and Pathan, Momina and Ottoboni, Sara and Prasad, Elke and Robertson, Murray and Mehta, Bhavik and McGowan, Mark and Siddique, Humera and Raval, Vishal and Pereira Diaz, Laura and Siddique, Mariam and Eales, William and Turner, Alice and Johnston, Blair and Robertson, John and Halbert, Gavin and Price, Chris and Benyahia, Brahim and Rielly, Chris and Sefcik, Jan and Nordon, Alison and McGlone, Thomas and Smith, Kenneth and Feilden, Helen and Houson, Ian and Florence, Alastair (2022) The CMAC MicroFactory : mefenamic acid. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Pathan, Momina and McGinty, John and Chong, Magdalene W. S. and Robertson, Murray and Ottoboni, Sara and Li, Wei and McGowan, Mark and Ojo, Ebenezer and Anwar, Ali and Brown, Cameron J. and Sefcik, Jan and Nordon, Alison and Johnston, Blair and Price, Chris J. and Rielly, Chris D. and Benyahia, Brahim and Houson, Ian and Florence, Alastair J (2022) Crystallisation MicroFactory test bed. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Ottoboni, Sara and Mehta, Bhavik and Gramadnikova, Ekaterina and Brown, Cameron J. and Mitchell, Niall A. (2022) Integrated filtration and washing modelling : optimization of impurity rejection for the filtration and washing of active pharmaceutical ingredients. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Li, Wei and Benyahia, Brahim and Rielly, Chris D. and McGinty, John and Chong, Magdalene W. S. and Ottoboni, Sara and Pathan, Momina and McGowan, Mark and Prasad, Elke and Robertson, Murray (2022) Model driven crystallization design and development for mefenamic acid. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Mehta, Bhavik and Brown, Cameron and Mitchell, Niall and Ottoboni, Sara (2022) Wet milling of mefenamic acid for seed generation : model-driven size reduction for maximizing yield. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Vassileiou, Antony D. and Robertson, Murray N. and Wareham, Bruce G. and Soundaranathan, Mithushan and Ottoboni, Sara and Florence, Alastair J. and Hartwig, Thoralf and Johnston, Blair F. (2022) A unified AI framework for solubility prediction across organic solvents. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

2021

Shahid, Muhid and Faure, Chloé and Ottoboni, Sara and Lue, Leo and Price, Chris (2021) Employing constant rate filtration to assess active pharmaceutical ingredient washing efficiency. Organic Process Research and Development, 26 (1). pp. 97-110. ISSN 1083-6160

Ottoboni, Sara and Wareham, Bruce and Vassileiou, Antony and Robertson, Murray and Brown, Cameron J. and Johnston, Blair and Price, Chris J. (2021) A novel integrated workflow for isolation solvent selection using prediction and modelling. Organic Process Research and Development, 25 (5). pp. 1143-1159. ISSN 1083-6160

Shahid, Muhid and Sanxaridou, Georgia and Ottoboni, Sara and Lue, Leo and Price, Chris (2021) Exploring the role of anti-solvent effects during washing on active pharmaceutical ingredient purity. Organic Process Research and Development, 25 (4). pp. 969-981. ISSN 1083-6160

Ottoboni, Sara and Shahid, Muhid and Martin, Alan and Kathyola, Thokozile and Das, Gunjan and Schroeder, Sven and Marathe, Shashidhara and Rau, Christopher and Wanelik, Kaz and Price, Chris John (2021) Fluid and impurity transport during online isolation experiments conducted with X-ray tomography. In: 13th World Filtration Congress, 2021-09-20 - 2021-09-24. (In Press)

2020

Ottoboni, Sara and Coleman, Simon J. and Steven, Christopher and Siddique, Mariam and Fraissinet, Marine and Joannes, Marion and Laux, Audrey and Barton, Alastair and Firth, Paul and Price, Chris J. and Mulheran, Paul A. (2020) Understanding API static drying with hot gas flow : design and test of a drying rig prototype and drying modelling development. Organic Process Research and Development, 24 (11). pp. 2505-2520. ISSN 1083-6160

Ottoboni, Sara and Shahid, Muhid and Steven, Christopher and Coleman, Simon and Meehan, Elizabeth and Barton, Alastair and Firth, Paul and Sutherland, Richard and Price, Chris J. (2020) Developing a batch isolation procedure and running it in an automated semi-continuous unit : AWL CFD25 case study. Organic Process Research and Development, 24 (4). pp. 520-539. ISSN 1083-6160

Ottoboni, S. and Šimurda, M. and Wilson, S. and Irvine, A. and Ramsay, F. and Price, C.J. (2020) Understanding effect of filtration and washing on dried product : paracetamol case study. Powder Technology, 366. pp. 305-323. ISSN 0032-5910

2019

Shahid, Muhid and Sanxaridou, Georgia and Ottoboni, Sara and Lue, Leo and Price, Chris (2019) Understanding and mitigating the consequences of undesired crystallisation taking place during washing of active pharmaceuticals. In: British Association of Crystal Growth 50th Annual Conference, 2019-07-09 - 2019-07-11, Sussex Place.

Ottoboni, Sara and Price, Chris J. and Steven, Christopher and Meehan, Elizabeth and Barton, Alastair and Firth, Paul and Mitchell, Andy and Tahir, Furqan (2019) Development of a novel continuous filtration unit for pharmaceutical process development and manufacturing. Journal of Pharmaceutical Sciences, 108 (1). pp. 372-381. ISSN 0022-3549

2018

Ottoboni, Sara and Chrubasik, Michael and Mir Bruce, Layla and Nguyen, Thai Thu Hien and Robertson, Murray and Johnston, Blair and Oswald, Iain D. H. and Florence, Alastair and Price, Chris (2018) Impact of paracetamol impurities on face properties : investigating the surface of single crystals using TOF-SIMS. Crystal Growth and Design, 18 (5). 2750–2758. ISSN 1528-7483

2017

Price, Chris John and Ottoboni, Sara (2017) Addressing the challenges of continuous filtration, washing and drying. In: Continuous manufacturing 2017, 2017-02-22 - 2017-02-23, Druids Glen Hotel.

2016

Ottoboni, S. and Price, C. J. and Steven, C. and Meehan, E. and Barton, A. and Mitchell, A. (2016) Development of a novel continuous filtration unit for pharmaceutical process development and manufacturing : a case study using paracetamol. In: Filtech, 2016-10-11 - 2016-10-13, Koelnmesse.

Ponzoni, Amani and Ottoboni, Sara and Guillizzoni, Manfredo and Zani, Maurizio and Gronchi, Paolo (2016) Properties of steel surfaces coated with organic molecules. In: XXX International Conference on Surface Modification Technologies (SMT30), 2016-06-29 - 2016-07-01, POLITECNICO DI MILANO, CAMPUS BOVISA.

Ottoboni, Sara and Chrubasik, Michael and Mir Bruce, Layla and Nguyen, Thai Thu Hien and Johnston, Blair and Florence, Alastair and Price, Chris John (2016) The impact of paracetamol impurities on face-specific properties : investigating the surface of single crystals using TOF-SIMS. In: Crystal Growth of Organic Materials, 2016-06-26 - 2016-06-30, University of Leeds.