Linking 3DP manufacturing with SIFT-MS volatiles organic compound analysis

Prasad, Elke and Bordos, Ecaterina and Langford, Vaughan and Perkins, Mark and Robertson, John and Halbert, Gavin W. (2023) Linking 3DP manufacturing with SIFT-MS volatiles organic compound analysis. In: AAPS 2023 PHARMSCI 360, 2023-10-22 - 2023-10-25, Orange County Convention Center.

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Abstract

3D printing (3DP) oral solid dose forms by Fused Filament Fabrication has gained increased interest in recent years. To facilitate efficient formulation and process development, some studies developed and implemented rheological and mechanical screening tests [1-3]. However, changes in the formulated polymeric system due to processing at elevated temperatures and shear have not been addressed. In this study, SIFT-MS Volatiles Organic Compound Analysis was employed to monitor a 3DP manufacturing process.

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• Item metadata

  Item type:	Conference or Workshop Item(Poster)
  ID code:	88723
  Dates:	Date Event 22 October 2023 Published
  Subjects:	Medicine > Pharmacy and materia medica > Pharmaceutical technology
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Technology and Innovation Centre > Continuous Manufacturing and Crystallisation (CMAC)
  Depositing user:	Pure Administrator
  Date deposited:	16 Apr 2024 11:08
  Last modified:	27 Apr 2024 00:44
  URI:	https://strathprints.strath.ac.uk/id/eprint/88723