Applications of dendrimers for brain delivery and cancer therapy

Somani, Sukrut and Dufès, Christine (2014) Applications of dendrimers for brain delivery and cancer therapy. Nanomedicine, 9 (15). pp. 2403-2414. ISSN 1743-5889 (

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Dendrimers are emerging as potential non-viral vectors for efficiently delivering drugs and nucleic acids to the brain and cancer cells. These polymers are highly branched, three-dimensional macromolecules with modifiable surface functionalities and available internal cavities that make them attractive as delivery systems for drug and gene delivery applications. This review highlights the recent therapeutic advances resulting from the use of dendrimers for brain targeting and cancer treatment.