Browse by Author or creator

2018

Raza, Syed A. and Schacht, Ulrich and Svoboda, Vaclav and Edwards, Darren P. and Florence, Alastair J. and Pulham, Colin R. and Sefcik, Jan and Oswald, Iain D. H. (2018) Rapid continuous antisolvent crystallization of multi-component systems. Crystal Growth and Design, 18 (1). pp. 210-218. ISSN 1528-7483

2017

S. de Moraes, Lygia and Edwards, Darren and Florence, Alastair J. and Johnston, Andrea and Johnston, Blair F. and Morrison, Catriona A. and Kennedy, Alan R. (2017) Aqueous solubility of organic salts. Investigating trends in a systematic series of 51 crystalline salt forms of methylephedrine. Crystal Growth and Design, 17 (6). pp. 3277-3286. ISSN 1528-7483

2013

Gillespie, Cheska and Kennedy, Alan R. and Edwards, Darren and Dowden, Lee and Daublain, Pierre and Halling, Peter (2013) Detailed study of precipitation of a poorly water soluble test compound using methodologies as in activity and solubility screening - mixing and automation effects. Combinatorial Chemistry and High Throughput Screening, 16 (8). pp. 636-643. ISSN 1386-2073

2012

Scullion, Paul and Edwards, Darren and McKinnon, Heather and Miller, Stewart and Watson, David and MacIntyre, Lynsey (2012) Analysis of changes in triacylglycerol ratios in mouse liver and plasma in response to a liver X receptor agonist. Metabolomics, 8 (1). pp. 74-85. ISSN 1573-3882

2011

Gillespie, Cheska and Halling, Peter and Edwards, Darren (2011) Monitoring of particle growth at a low concentration of a poorly water soluble drug using the NanoSight LM20. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 384 (1-3). pp. 233-239. ISSN 0927-7757

Cowley, Phillip M and Baker, James and Buchanan, Kirsteen I and Carlyle, Ian and Clark, John K and Clarkson, Thomas R and Deehan, Maureen and Edwards, Darren and Kiyoi, Yasuko and Martin, Iain and Osbourn, Dawn and Walker, Glenn and Ward, Nick and Wishart, Grant (2011) Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB1 antagonists. Bioorganic and Medicinal Chemistry Letters, 21 (7). pp. 2034-2039. ISSN 0960-894X

Kiyoi, Takao and Adam, Julia M and Clark, John K and Davies, Keneth and Easson, Anna-Marie and Edwards, Darren and Feilden, Helen and Fields, Ruth and Francis, Stuart and Jeremiah, Fiona and McArthur, Duncan and Morrison, Angus J and Prosser, Alan and Ratcliffe, Paul D and Schulz, Jurgen and Wishart, Grant and Baker, James and Campbell, Robert and Cottney, Jean E and Deehan, Maureen and Epemolu, Ola and Evans, Louise (2011) Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists. Bioorganic and Medicinal Chemistry Letters, 21 (6). pp. 1748-1753. ISSN 0960-894X

2010

Letourneau, Jeffrey J and Jokiel, Patrick and Olson, John and Riviello, Christopher M and Ho, Koc-Kan and McAleer, Lihong and Yang, Jingchun and Swanson, Robert N and Baker, James and Cowley, Phillip and Edwards, Darren and Ward, Nick and Ohlmeyer, Michael H J and Webb, Maria L (2010) Identification and hit-to-lead optimization of a novel class of CB1 antagonists. Bioorganic and Medicinal Chemistry Letters, 20 (18). pp. 5449-5453. ISSN 0960-894X

Kiyoi, Takao and York, Mark and Francis, Stuart and Edwards, Darren and Walker, Glenn and Houghton, Andrea K and Cottney, Jean E and Baker, James and Adam, Julia M (2010) Design, synthesis, and structure-activity relationship study of conformationally constrained analogs of indole-3-carboxamides as novel CB1 cannabinoid receptor agonists. Bioorganic and Medicinal Chemistry Letters, 20 (16). pp. 4918-4921. ISSN 0960-894X