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Article

Rawling, Michael and Rowley, Julian and Campbell, Matthew and Kennedy, Alan and Parkinson, John and Tomkinson, Nick (2014) Mechanistic insights into the malonoyl peroxide syn-dihydroxylation of alkenes. Chemical Science, 2014 (5). pp. 1777-1785. ISSN 2041-6520

Trump, Ryan P. and Bresciani, Stefano and Cooper, Anthony W. J. and Tellam, James P. and Wojno, Justyna and Blaikley, John and Orband-Miller, Lisa A. and Kashatus, Jennifer A. and Boudjelal, Mohamed and Dawson, Helen C. and Loudon, Andrew and Ray, David and Grant, Daniel and Farrow, Stuart N. and Willson, Timothy M. and Tomkinson, Nicholas C. O. (2013) Optimized chemical probes for REV-ERB alpha. Journal of Medicinal Chemistry, 56 (11). pp. 4729-4737. ISSN 0022-2623

Rowley, Julian and Yau, Sze Chak and Kariuki, Benson M and Kennedy, Alan and Tomkinson, Nick (2013) Readily accessible chiral at nitrogen cage structures. Organic and Biomolecular Chemistry, 11 (13). pp. 2198-2205. ISSN 1477-0520

Knapp, Stefan and Arruda, Paulo and Blagg, Julian and Burley, Stephen and Drewery, David and Edwards, Aled and Fabbro, Doriano and Gillespie, Paul and Gray, Nathanael S and Kuster, Bernhard and Lackey, Karen E and Mazzafera, Paulo and Tomkinson, Nick and Willson, Timothy and Workman, Paul and Zuercher, William (2013) A public-private partnership to unlock the untargeted kinome. Nature Chemical Biology, 9 (1). pp. 3-6. ISSN 1552-4450

Rawling, Michael and Tomkinson, Nick (2013) Metal-free syn-dioxygenation of alkenes. Organic and Biomolecular Chemistry, 11 (9). pp. 1434-1440. ISSN 1477-0520

Picon, Sylvain and Rawling, Michael and Campbell, Matthew and Tomkinson, Nick (2012) Alkene dihydroxylation with malonoyl peroxides : catalysis using fluorinated alcohols. Organic Letters, 14 (24). pp. 6250-6253. ISSN 1523-7060

Smithen, Deborah and Mathews, Christopher and Tomkinson, Nick (2012) Asymmetric alpha-oxyacylation of cyclic ketones. Organic and Biomolecular Chemistry, 10 (18). pp. 3756-3762. ISSN 1477-0520

Tomkinson, Nick and Jones, Kevin M (2012) Metal-free dihydroxylation of alkenes using cyclobutane malonoyl peroxide. Journal of Organic Chemistry, 77 (2). pp. 921-928. ISSN 0022-3263

Samulis, Leopold and Tomkinson, Nicholas C.O. (2011) Preparation of the MacMillan Imidazolidinones. Tetrahedron, 67 (23). pp. 4263-4267. ISSN 0040-4020

Brazier, John B and Hopkins, Greg P and Jirari, Meriem and Mutter, Shaun and Pommereuil, Ronan and Samulis, Leopold and Platts, James A and Tomkinson, Nicholas C.O. (2011) Iminium ion catalysis: direct comparison of imidazolidinone and diarylprolinol ether reactivity. Tetrahedron Letters, 52 (21). pp. 2783-2785. ISSN 0040-4039

Brazier, John B. and Jones, Kevin M. and Platts, James A. and Tomkinson, Nicholas C.O. (2011) On the roles of protic solvents in imidazolidinone-catalyzed transformations. Angewandte Chemie, 50 (7). pp. 1613-1616. ISSN 0044-8249

Griffith, James C and Jones, Kevin M and Picon, Sylvain and Rawling, Michael J and Kariuki, Benson M and Campbell, Matthew and Tomkinson, Nicholas C. O. (2010) Alkene syn dihydroxylation with malonoyl peroxides. Journal of the American Chemical Society, 132 (41). pp. 14409-14411. ISSN 0002-7863

Porzelle, Achim and Cooper, Anthony W. J. and Woodrow, Michael D and Tomkinson, Nicholas C.O. (2010) 2-aminophenols containing electron-withdrawing groups from N-aryl hydroxylamines. Synlett, 2010 (16). pp. 2471-2473. ISSN 0936-5214

Porzelle, Achim and Woodrow, Michael D and Tomkinson, Nicholas C. O. (2010) Rearrangement strategy for the synthesis of 2-aminoanilines. Organic Letters, 12 (7). pp. 1492-1495. ISSN 1523-7060

Porzelle, Achim and Woodrow, Michael D and Tomkinson, Nicholas (2010) Synthesis of benzoxazolones from nitroarenes or aryl halides. Organic Letters, 12 (4). pp. 812-815. ISSN 1523-7060

Brazier, John B. and Tomkinson, Nicholas C. O. (2010) Secondary and primary amine catalysts for iminium catalysis. Current Topics in Medicinal Chemistry, 291 (Asymme). pp. 281-347.

Vaismaa, Matti J. P. and Yau, Sze Chak and Tomkinson, Nicholas C. O. (2009) Organocatalytic α-oxybenzoylation of aldehydes. Tetrahedron Letters, 50 (26). pp. 3625-3627. ISSN 0040-4039

Contiero, Fanny and Jones, Kevin M. and Matts, Edward A. and Porzelle, Achim and Tomkinson, Nicholas C. O. (2009) Direct preparation of benzofurans from O-arylhydroxylamines. Synlett (18). pp. 3003-3006. ISSN 0936-5214

Porzelle, Achim and Woodrow, Michael D. and Tomkinson, Nicholas C. O. (2009) Facile procedure for the synthesis of N-aryl-N-hydroxy carbamates. Synlett (5). pp. 798-802. ISSN 0936-5214

Porzelle, Achim and Woodrow, Michael D. and Tomkinson, Nicholas C. O. (2009) Palladium-catalyzed coupling of hydroxylamines with aryl bromides, chlorides, and iodides. Organic Letters, 11 (1). pp. 233-236. ISSN 1523-7060

Brazier, John B. and Evans, Gareth and Gibbs, Timothy J. K. and Coles, Simon J. and Hursthouse, Michael B. and Platts, James A. and Tomkinson, Nicholas C. O. (2009) Solution phase, solid state, and theoretical investigations on the MacMillan imidazolidinone. Organic Letters, 11 (1). pp. 133-136. ISSN 1523-7060

Tomkinson, Nick and Porzelle, Achim and Cavill, Julie L. and Elliott, Richard L. and Evans, Gareth and Gibbs, Timothy J. K. and Jones, Ian L. and Platts, James A (2009) The alpha-effect in cyclic secondary amines: new scaffolds for iminium ion accelerated transformations. Tetrahedron, 65. p. 9961. ISSN 0040-4020

Evans, Gareth and Gibbs, Timothy J. K. and Jenkins, Robert L. and Coles, Simon J. and Hursthouse, Michael B. and Platts, James A. and Tomkinson, Nicholas C. O. (2008) Kinetics of iminium ion catalysis. Agewandte Chemie-International Edition, 47 (15). pp. 2820-2823. ISSN 1433-7851

Jones, Kerri L. and Porzelle, Achim and Hall, Adrian and Woodrow, Michael D. and Tomkinson, Nicholas C. O. (2008) Copper-catalyzed coupling of hydroxylamines with aryl iodides. Organic Letters, 10 (5). pp. 797-800. ISSN 1523-7060

Knowles, Deborah A. and Mathews, Christopher J. and Tomkinson, Nicholas C. O. (2008) Oxidation of primary amines to ketones. Synlett (18). pp. 2769-2772. ISSN 0936-5214

Porzelle, Achim and Woodrow, Michael D. and Tomkinson, Nicholas C. O. (2008) Rearrangement of differentially protected N-arylhydroxylamines. European Journal of Organic Chemistry (30). pp. 5135-5143. ISSN 1434-193X

Gibbs, Timothy J. K. and Platts, Jamie A. and Tomkinson, Nicholas C. O. (2007) Chemical and theoretical tools for understanding iminium ion catalysis. Abstracts of papers - American Chemical Society, 234. ORGN-396. ISSN 0065-7727

Gibbs, Timothy J. K. and Elliott, Richard L. and Evans, Gareth and Jones, Ian L. and Platts, Jamie A. and Tomkinson, Nicholas C. O. (2007) Structure activity relationships of secondary amines in iminium ion catalysis. Abstracts of papers - American Chemical Society, 234. ORGN-631. ISSN 0065-7727

Davies, Huw J. and Ruda, Antionio M. and Tomkinson, Nicholas C. O. (2007) Aminocatalysis of the Baylis-Hillman reaction. An important solvent effect. Tetrahedron Letters, 48 (8). pp. 1461-1464. ISSN 0040-4039

John, Oliver R. S. and Killeen, Niall M. and Knowles, Deborah A. and Yau, Sze Chak and Bagley, Mark C. and Tomkinson, Nicholas C. O. (2007) Direct α-oxytosylation of carbonyl compounds: one-pot synthesis of heterocycles. Organic Letters, 9 (20). pp. 4009-4012. ISSN 1523-7060

Jones, Ian L. and Schofield, Daniel J. and Strevens, Robert R. and Horton, Peter N. and Hursthouse, Michael B. and Tomkinson, Nicholas C. O. (2007) Novel steroid mimics: synthesis of tri- and tetra-substituted oxamides and oxoamides. Tetrahedron Letters, 48 (4). pp. 521-525. ISSN 0040-4039

Hall, Adrian and Huguet, Edouard P. and Jones, Kerri L. and Jones, Teyrnon C. and Killeen, Niall M. and Yau, Sze Chak and Tomkinson, Nicholas C. O. (2007) The direct formation of α-carbamates from carbonyl compounds. Synlett (2). pp. 293-297. ISSN 0936-5214

Gibbs, Timothy J. K. and Boomhoff, Michael and Tomkinson, Nicholas C. O. (2007) A mild and efficient method for the one-pot monocarboxymethylation of primary amines. Synlett (10). pp. 1573-1576. ISSN 0936-5214

Jones, Teyrnon C. and Tomkinson, Nicholas C. O. (2007) A practical procedure for carbonyl α-oxidation: synthesis of (2-benzoyloxy)-1,4-cyclohexanedione mono-ethylene ketal. Organic Syntheses, 84. pp. 233-241. ISSN 0078-6209

Ruda, Antonio M. and Cavill, Julie L. and Tomkinson, Nicholas C. O. (2006) ORGN 140-8-Aryl menthamine-derived scaffolds for iminium ion catalysis. Abstracts of papers - American Chemical Society, 232. 140-ORGN. ISSN 0065-7727

Strevens, Robert and Tomkinson, Nicholas C. O. (2006) Design, synthesis and evaluation of novel steroid mimics. Abstracts of papers - American Chemical Society, 231. MEDI-043. ISSN 0065-7727

Evans, Gareth J. S. and White, Katherine and Platts, James A. and Tomkinson, Nicholas C. O. (2006) Computational study of iminium ion formation: effects of amine structure. Organic and Biomolecular Chemistry, 4 (13). pp. 2616-2627. ISSN 1477-0520

Jones, Teyrnon C. and Killeen, Niall M. and Jones, Kerri L. and Tomkinson, Nicholas C. O. and Hall, Adrian. (2006) New reagents for the metal-free one-pot alpha-functionalisation of carbonyl compounds. Abstracts of papers - American Chemical Society, 231. 365-ORGN. ISSN 0065-7727

Hall, Adrian and Jones, Kerri L. and Jones, Teyrnon C. and Killeen, Niall M. and Porzig, Robert and Taylor, Paul H. and Yau, Sze Chak and Tomkinson, Nicholas C. O. (2006) The direct introduction of carbonates α to carbonyl groups. Synlett (20). pp. 3435-3438. ISSN 0936-5214

Bridgeman, Eve and Tomkinson, Nicholas C. O. (2006) A simple method for the preparation of di-, tri-, and tetrasubstituted non-symmetrical ureas. Synlett (2). pp. 243-246. ISSN 0936-5214

Gibbs, Timothy J. K. and Tomkinson, Nicholas C. O. (2005) Aminocatalytic preparation of bisindolylalkanes. Organic and Biomolecular Chemistry, 3 (22). pp. 4043-4045. ISSN 1477-0520

Bridgeman, Eve and Cavill, Julie L. and Schofield, Daniel J. and Wilkins, Derek S. and Tomkinson, Nicholas C. O. (2005) Novel steroid mimics directed towards the estradiol skeleton. Tetrahedron Letters, 46 (49). pp. 8521-8524. ISSN 0040-4039

Cavill, Julie L. and Elliott, Richard L. and Evans, Gareth and Jones, Ian L. and Platts, James A. and Ruda, Antonio M. and Tomkinson, Nicholas C. O. (2005) The α-effect in iminium ion catalysis. Tetrahedron, 62 (2-3). pp. 410-421. ISSN 0040-4020

Beshara, Cory S. and Hall, Adrian and Jenkins, Robert L. and Jones, Kerri L. and Jones, Teyrnon C. and Killeen, Niall M. and Taylor, Paul H. and Thomas, Stephen P. and Tomkinson, Nicholas C. O. (2005) A general method for the α-acyloxylation of carbonyl compounds. Organic Letters, 7 (25). pp. 5729-5732. ISSN 1523-7060

Harris, Lisa D. and Jenkins, Robert L. and Tomkinson, Nicholas C. O. (2005) The modulation of face-face π-π interactions in Lewis acid catalysis. Tetrahedron Letters, 46 (10). pp. 1627-1629. ISSN 0040-4039

Beshara, Cory S. and Hall, Adrian and Jenkins, Robert L. and Jones, Teyrnon C. and Parry, Rachael T. and Thomas, Stephen P. and Tomkinson, Nicholas C. O. (2005) A simple method for the α-oxygenation of aldehydes. Chemical Communications (11). pp. 1478-1480. ISSN 1359-7345

Bagley, Mark C. and Hughes, David D. and Lubinu, M. Caterina and Merritt, Eleanor A. and Taylor, Paul H. and Tomkinson, Nicholas C. O. (2004) Microwave-assisted synthesis of pyrimidine libraries. QSAR and Combinatorial Science, 23 (10). pp. 859-867. ISSN 1611-020X

Harris, Lisa D. and Platts, James A. and Tomkinson, Nicholas C. O. (2003) Enhanced π···π interactions in α,β-unsaturated carbonyls. Organic and Biomolecular Chemistry, 1 (3). pp. 457-459. ISSN 1477-0520

Cavill, Julie L. and Peters, Jens-Uwe and Tomkinson, Nicholas C. O. (2003) Iminium ion catalysis: Use of the α-effect in the acceleration of the Diels-Alder reaction. Chemical Communications (6). pp. 728-729. ISSN 1359-7345

Coogan, Michael P. and Haigh, Robert and Hall, Adrian and Harris, Lisa D. and Hibbs, David E. and Jenkins, Robert L. and Jones, Claire L. and Tomkinson, Nicholas C. O. (2003) A new chiral diol derived from tetralone for the complexation of Lewis acids. Tetrahedron, 59 (37). pp. 7389-7395. ISSN 0040-4020

Hall, Adrian and Harris, Lisa D. and Jones, Claire L. and Jenkins, Robert L. and Tomkinson, Nicholas C. O. (2003) A simple and versatile method to determine the enantiomeric purity of Diels-Alder adducts. Tetrahedron Letters, 44 (1). pp. 111-114. ISSN 0040-4039

Jones, D. N. and Maybury, M. W. J. and Swallow, S. and Tomkinson, N. C. O. and Wood, W. W. (2001) A concise synthesis of homochiral trans-perhydroazulenes and trans-hydrindanes. Tetrahedron Letters, 42 (11). pp. 2193-2195. ISSN 0040-4039

Spencer, Thomas A. and Li, Dansu and Russel, Jonathon S. and Tomkinson, Nicholas C. O. and Willson, Timothy M. (2000) Further studies on the synthesis of 24(S),25-epoxycholesterol. A new, efficient preparation of desmosterol. Journal of Organic Chemistry, 65 (7). pp. 1919-1923. ISSN 0022-3263

Jones, Stacey A. and Moore, Linda B. and Shenk, Jennifer L. and Wisely, G. Bruce and Hamilton, Geraldine A. and McKee, David D. and Tomkinson, Nicholas C. O. and LeCluyse, Edward L. and Lambert, Millard H. and Willson, Timothy M. and Kliewer, Steven A. and Moore, John T. (2000) The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution. Journal of Molecular Endocrinology, 14 (1). pp. 27-39. ISSN 0952-5041

Adams, Harry and Bell, Richard and Cheung, Yiu-Yin and Jones, D. Neville and Tomkinson, Nicholas C. O. (1999) The cleavage of meso-epoxides with homochiral thiols: synthesis of (+)-trans-2-mercaptocyclohexanol and (-)-trans-2-mercaptocyclohexanol. Tetrahedron: Asymmetry, 10 (21). pp. 4129-4142. ISSN 0957-4166

Parks, Derek J. and Tomkinson, Nicholas C. O. and Villeneuve, Manon S. and Blanchard, Steven G. and Willson, Timothy M. (1998) Differential activity of rosiglitazone enantiomers at PPARγ. Bioorganic and Medicinal Chemistry Letters, 8 (24). pp. 3657-3658. ISSN 0960-894X

Tomkinson, Nicholas C. O. and Willson, Timothy M. and Russel, Jonathon S. and Spencer, Thomas A. (1998) Efficient, stereoselective synthesis of 24(S),25-epoxycholesterol. Journal of Organic Chemistry, 63 (26). pp. 9919-9923. ISSN 0022-3263

Messeri, Tommaso and Sternbach, Daniel D. and Tomkinson, Nicholas C. O. (1998) A novel deprotection/functionalization sequence using 2,4-dinitrobenzenesulfonamide. Part 2. Tetrahedron Letters, 39 (13). pp. 1673-1676. ISSN 0040-4039

Messeri, Tommaso and Sternbach, Daniel D. and Tomkinson, Nicholas C. O. (1998) A novel deprotection/functionalization sequence using 2,4-dinitrobenzenesulfonamide: Part 1. Tetrahedron Letters, 39 (13). pp. 1669-1672. ISSN 0040-4039

Adams, Harry and Anderson, James C. and Bell, Richard and Neville Jones, D. and Peel, Michael R. and Tomkinson, Nicholas C. O. (1998) The synthesis and Diels-Alder reactions of (E)- and (Z)-1-methoxy-3-(phenylsulfinyl)-1,3-butadienes. Journal of the Chemical Society, Perkin Transactions 1 (23). pp. 3967-3974. ISSN 1472-7781

Brown, Peter J. and Smith-Oliver, Tracey A. and Charifson, Paul S. and Tomkinson, Nicholas C. O. and Fivush, Adam M. and Sternbach, Daniel D. and Wade, Laura E. and Orband-Miller, Lisa and Parks, Derek J. and Blanchard, Steven G. (1997) Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library. Chemistry and Biology, 4 (12). pp. 909-918. ISSN 1074-5521

Tomkinson, Nicholas C. O. and Sefler, Andrea M. and Plunket, Kelli D. and Blanchard, Steven G. and Parks, Derek J. and Willson, Timothy M. (1997) Solid-phase synthesis of hybrid thiazolidinedione-fatty acid PPARγ ligands. Bioorganic and Medicinal Chemistry Letters, 7 (19). pp. 2491-2496. ISSN 0960-894X

Jones, D. Neville and Maybury, Mark W. J. and Swallow, Steven and Tomkinson, Nicholas C. O. (1993) Novel cyclizations involving vinyl sulfones: stereoselective construction of perhydroazulenes and trans-hydrindanes. Tetrahedron Letters, 34 (52). pp. 8553-8556. ISSN 0040-4039

Book Section

Rowley, Julian and Tomkinson, Nick (2013) Organocatalyzed transformations of á, â-unsaturated carbonyl compounds through iminium ion intermediates. In: Asymmetric Synthesis II. Wiley, pp. 29-34. ISBN 9783527329212

Tomkinson, Nick and Rowley, Julian (2012) Organocatalysed transformations of alpha,beta-unsaturated carbonyl compoundsthrough iminium ion intermediates. In: Asymmetric synthesis. Wiley-VCH, Weinheim, pp. 29-34. ISBN 9783527329007

Chappelle, Michael R. and Morgan, Alan D. and Tomkinson, Nicholas C. O. and Willson, Timothy M. (2001) Tritium labeling of the PXR ligand GW5801 - an unexpected tritium exchange reaction. In: Synthesis and applications of isotopically labelled compounds, volume 7. Wiley-Blackwell, pp. 80-83. ISBN 0471495018

Tomkinson, Nicholas C. O. (2001) Conjugate addition reactions. In: Second supplements to the 2nd edition of Rodd's chemistry of carbon compounds. Elsevier, pp. 199-258. ISBN 9780444533470

Conference or Workshop Item

Brazier, John B. and Platts, Jamie A. and Tomkinson, Nicholas C. O. (2009) Iminium ion catalysis: tools and observations. In: UNSPECIFIED.

Porzelle, Achim and Tomkinson, Nicholas C. O. (2009) Palladium catalyzed N-arylation of hydroxylamines. In: UNSPECIFIED.

Porzelle, Achim and Tomkinson, Nicholas C. O. (2009) Rearrangement strategies for aryl-heteroatom bond formation. In: UNSPECIFIED.

Taylor, Paul H. and Arnott, Euan A. and Tomkinson, Nicholas C. O. (2008) Mechanistic investigations into a novel C-O bond construction process. In: American Chemical Society , USA, 2011-03-31.

Taylor, Paul H. and Arnott, Euan A. and Tomkinson, Nicholas C. O. (2008) Metal-free α-oxygenation of carbonyl compounds: Methodology and mechanism. In: American Chemical Society , USA, 2011-03-31.

Knowles, Deborah A. and Matthews, Christopher J. and Tomkinson, Nicholas C. O. (2008) Novel chiral hydroxylamines for the asymmetric α-functionalisation of carbonyl compounds. In: UNSPECIFIED.

Knowles, Deborah A. and Matthews, Christopher J. and Tomkinson, Nicholas C. O. (2008) An asymmetric method for the α-oxyacylation of carbonyl compounds. In: American Chemical Society , USA, 2011-03-31.

Jones, Teyrnon C. and Tomkinson, Nicholas C. O. (2006) New methods in metal-free organic synthesis : a practical procedure for carbonyl α-oxidation. In: 231st ACS National Meeting, 2006-03-26 - 2006-03-30, Atlanta, GA.

Spencer Thomas A., Jr. and Li, Dansu and Russel, Jonathon S. and Tomkinson, Nicholas C. O. and Willson, Timothy M. (2000) Further studies on synthesis of 24(S),25-epoxycholesterol : new efficient preparation of desmosterol. In: 219th Meeting of the American Chemical Society, 2000-03-26 - 2000-03-30, San Francisco.

Tomkinson, Nicholas C. O. and Willson, Timothy M. and Spencer, Thomas A. and Russell, Jonathon S. (1998) Efficient, stereoselective synthesis of 24(S),25-epoxycholesterol. In: 216th National Meeting of the American Chemical Society, 1998-08-23 - 1998-08-27, Boston.

This list was generated on Wed Oct 22 14:45:12 2014 BST.