Aryldiazonium tetrafluoroborate salts as green and efficient coupling partners for the Suzuki-Miyaura reaction : from optimisation to mole scale

Colleville, Aymeric P. and Horan, Richard A. J. and Tomkinson, Nick C. O. (2014) Aryldiazonium tetrafluoroborate salts as green and efficient coupling partners for the Suzuki-Miyaura reaction : from optimisation to mole scale. Organic Process Research and Development, 18 (9). 1128–1136. ISSN 1083-6160 (https://doi.org/10.1021/op5002353)

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Abstract

The use of aryldiazonium tetrafluoroborate salts as coupling partners in the Suzuki-Miyaura reaction was investigated from a process chemistry perspective including safety evaluation, solvent and catalyst screening and multi-variate factor optimization. Optimised conditions were applied to a range of substrates to evaluate the scope and limitations of the reaction and one example was carried out on mole-scale to demonstrate the practicality and scalability of the process

ORCID iDs

Colleville, Aymeric P. ORCID logoORCID: https://orcid.org/0000-0003-3094-5155, Horan, Richard A. J. and Tomkinson, Nick C. O. ORCID logoORCID: https://orcid.org/0000-0002-5509-0133;
  • Item type:Article
    ID code:56512
    Dates:
    Date
    Event
    12 August 2014
    Published
    12 August 2014
    Accepted
    Keywords:aryldiazonium tetrafluoroborate salts, Suzuki–Miyaura reaction, mole scale, Chemistry, Organic Chemistry, Physical and Theoretical Chemistry
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:25 May 2016 11:01
    Last modified:30 Sep 2022 01:29
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/56512
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