Differential activity of rosiglitazone enantiomers at PPARγ
Parks, Derek J. and Tomkinson, Nicholas C. O. and Villeneuve, Manon S. and Blanchard, Steven G. and Willson, Timothy M. (1998) Differential activity of rosiglitazone enantiomers at PPARγ. Bioorganic and Medicinal Chemistry Letters, 8 (24). pp. 3657-3658. ISSN 0960-894X
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Abstract
Anal. of the enantiomers of rosiglitazone in a PPARγ binding assay suggests that the (S)-(-)- isomer is responsible for the antidiabetic activity.
Creators(s): |
Parks, Derek J., Tomkinson, Nicholas C. O. ![]() | Item type: | Article |
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ID code: | 34216 |
Keywords: | rosiglitazone enantiomers , rosiglitazone , antidiabetic activity, Chemistry, Biochemistry, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Molecular Biology, Clinical Biochemistry |
Subjects: | Science > Chemistry |
Department: | Faculty of Science > Pure and Applied Chemistry |
Depositing user: | Pure Administrator |
Date deposited: | 20 Oct 2011 15:22 |
Last modified: | 20 Jan 2021 19:39 |
URI: | https://strathprints.strath.ac.uk/id/eprint/34216 |
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