Iminium ion catalysis: direct comparison of imidazolidinone and diarylprolinol ether reactivity

Brazier, John B and Hopkins, Greg P and Jirari, Meriem and Mutter, Shaun and Pommereuil, Ronan and Samulis, Leopold and Platts, James A and Tomkinson, Nicholas C.O. (2011) Iminium ion catalysis: direct comparison of imidazolidinone and diarylprolinol ether reactivity. Tetrahedron Letters, 52 (21). pp. 2783-2785. ISSN 0040-4039

[thumbnail of Tomkinson.1.TL2011.docx] Microsoft Word
Tomkinson.1.TL2011.docx
Accepted Author Manuscript

Download (325kB)

    Abstract

    Comparison of the relative reactivities of the benchmark catalysts for iminium ion catalysed Diels-Alder cycloaddition under optimised literature conditions showed the imidazolidinone scaffold to possess significantly superior levels of activity in the Diels-Alder cycloaddition when compared to diarylprolinol silyl ethers.

    ORCID iDs

    Brazier, John B, Hopkins, Greg P, Jirari, Meriem, Mutter, Shaun, Pommereuil, Ronan, Samulis, Leopold, Platts, James A and Tomkinson, Nicholas C.O. ORCID logoORCID: https://orcid.org/0000-0002-5509-0133;