Aminocatalysis of the Baylis-Hillman reaction. An important solvent effect

Davies, Huw J. and Ruda, Antionio M. and Tomkinson, Nicholas C. O. (2007) Aminocatalysis of the Baylis-Hillman reaction. An important solvent effect. Tetrahedron Letters, 48 (8). pp. 1461-1464. ISSN 0040-4039

Full text not available in this repository.Request a copy from the Strathclyde author

Abstract

Examination of the amino-catalytic Baylis-Hillman reaction in the presence of proline and imidazole has revealed that water plays a crucial role in the acceleration of the reaction, allowing for excellent yields of the adduct between Me vinyl ketone and a variety of aldehydes.