A simple method for the preparation of di-, tri-, and tetrasubstituted non-symmetrical ureas

Bridgeman, Eve and Tomkinson, Nicholas C. O. (2006) A simple method for the preparation of di-, tri-, and tetrasubstituted non-symmetrical ureas. Synlett (2). pp. 243-246. ISSN 0936-5214

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Abstract

The synthesis of a series of di-, tri-, and tetrasubstituted non-sym. ureas is described. Di- and trisubstituted ureas are prepd. in excellent yield by treatment of a Ph carbamate in a self-tunable single-mode microwave synthesizer with a primary or secondary amine. The synthetically more challenging tetrasubstituted urea can be prepd. using the 4-nitrophenyl carbamate and a secondary amine.

Creators(s): Bridgeman, Eve and Tomkinson, Nicholas C. O. ORCID logoORCID: https://orcid.org/0000-0002-5509-0133;
Item type:Article
ID code:34190
Keywords:urea , carbamate , microwave-assisted synthesis , Chemistry, Organic Chemistry
Subjects:Science > Chemistry
Department:Faculty of Science > Pure and Applied Chemistry
Depositing user: Pure Administrator
Date deposited:20 Oct 2011 14:04
Last modified:01 Jan 2021 10:00
URI:https://strathprints.strath.ac.uk/id/eprint/34190
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