Copper-catalyzed coupling of hydroxylamines with aryl iodides.

Jones, Kerri L. and Porzelle, Achim and Hall, Adrian and Woodrow, Michael D. and Tomkinson, Nicholas C. O. (2008) Copper-catalyzed coupling of hydroxylamines with aryl iodides. Organic Letters, 10 (5). pp. 797-800. ISSN 1523-7060

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Official URL: https://doi.org/10.1021/ol7029273

Abstract

An efficient method for the copper-catalyzed N-arylation of hydroxylamines with aryl iodides is described. A variety of N- and O-functionalized hydroxylamines, e.g., I, were transformed in good to excellent yield with a broad range of aryl coupling partners. Methods for the selective deprotection of either the N- or O-substituents for further functionalization are also described.

Author(s):	Jones, Kerri L., Porzelle, Achim, Hall, Adrian, Woodrow, Michael D. and Tomkinson, Nicholas C. O. ORCID: https://orcid.org/0000-0002-5509-0133
Item type:	Article
ID code:	34172
Notes:	M1 - Copyright (C) 2011 American Chemical Society (ACS). All Rights Reserved. CAPLUS AN 2008:102150(Journal)
Keywords:	aryl iodides , copper-catalyzed N-arylation, aryl coupling partners, Chemistry, Biochemistry, Organic Chemistry, Physical and Theoretical Chemistry
Subjects:	Science > Chemistry
Department:	Faculty of Science > Pure and Applied Chemistry
Depositing user:	Pure Administrator
Date deposited:	12 Oct 2011 15:57
Last modified:	26 Jul 2019 02:21
URI:	https://strathprints.strath.ac.uk/id/eprint/34172
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