Copper-catalyzed coupling of hydroxylamines with aryl iodides.

Jones, Kerri L. and Porzelle, Achim and Hall, Adrian and Woodrow, Michael D. and Tomkinson, Nicholas C. O. (2008) Copper-catalyzed coupling of hydroxylamines with aryl iodides. Organic Letters, 10 (5). pp. 797-800. ISSN 1523-7060 (https://doi.org/10.1021/ol7029273)

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Abstract

An efficient method for the copper-catalyzed N-arylation of hydroxylamines with aryl iodides is described. A variety of N- and O-functionalized hydroxylamines, e.g., I, were transformed in good to excellent yield with a broad range of aryl coupling partners. Methods for the selective deprotection of either the N- or O-substituents for further functionalization are also described.

ORCID iDs

Jones, Kerri L., Porzelle, Achim, Hall, Adrian, Woodrow, Michael D. and Tomkinson, Nicholas C. O. ORCID logoORCID: https://orcid.org/0000-0002-5509-0133;
  • Item type:Article
    ID code:34172
    Dates:
    Date
    Event
    2008
    Published
    26 January 2008
    Published Online
    Notes:M1 - Copyright (C) 2011 American Chemical Society (ACS). All Rights Reserved. CAPLUS AN 2008:102150(Journal)
    Keywords:aryl iodides , copper-catalyzed N-arylation, aryl coupling partners, Chemistry, Biochemistry, Organic Chemistry, Physical and Theoretical Chemistry
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:12 Oct 2011 15:57
    Last modified:29 Sep 2022 01:17
    URI:https://strathprints.strath.ac.uk/id/eprint/34172
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