Items where department is "Pharmaceutical Sciences"

Khalaf, Abedawn I and Huggan, Judith and Suckling, Colin J and Gibson, Colin L and Stewart, Kirsten and Giordani, Federica and Barrett, Michael P. and Wong, Pui Ee and Barrack, Keri L and Hunter, William N (2014) Structure based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1. Journal of Medicinal Chemistry, 57 (15). pp. 6479-6494. ISSN 0022-2623

Boateng, J. S. and Matthews, Kerr H. and Auffret, Anthony D. and Humphrey, Mike J. and Eccleston, Gillian M. and Stevens, Howard N. (2012) Comparison of the in vitro release characteristics of mucosal freeze-dried wafers and solvent-cast films containing an insoluble drug. Drug Development and Industrial Pharmacy, 38 (1). pp. 47-54. ISSN 0363-9045

Spencer, John and Rathnam, Rajendra P. and Harvey, Alan L. and Clements, Carol J. and Clark, Rachel L. and Barrett, Michael P. and Wong, Pui Ee and Male, Louise and Coles, Simon J. and Mackay, Simon P. (2011) Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity. Bioorganic and Medicinal Chemistry, 19 (5). pp. 1802-1815.

Ghimire, Manish and Hodges, Lee Ann and Band, Janet and Lindsay, Blythe and O'Mahony, Bridget and McInnes, Fiona J and Mullen, Alexander B and Stevens, Howard N E (2011) Correlation between in vitro and in vivo erosion behaviour of erodible tablets using gamma scintigraphy. European Journal of Pharmaceutics and Biopharmaceutics, 77 (1). pp. 148-157.

Rhodes, Sinéad and Riby, D.M. and Matthews, K. and Coghill, D.R. (2011) Attention-deficit/hyperactivity disorder and Williams syndrome: Shared behavioral and neuropsychological profiles. Journal of Experimental and Clinical Neuropsychology, 33 (1). pp. 147-156. ISSN 1380-3395

Vincent, Isabel M and Creek, Darren and Watson, David G and Kamleh, Mohammed A and Woods, Debra J and Wong, Pui Ee and Burchmore, Richard J S and Barrett, Michael P (2010) A molecular mechanism for eflornithine resistance in African trypanosomes. PLOS Pathogens, 6 (11). e1001204.

Wong, P.E. and Tetley, L. and Dufès, C. and Chooi, K.W. and Bolton, K. and Schätzlein, A.G. and Uchegbu, I.F. (2010) Polyamine aza-cyclic compounds demonstrate anti-proliferative activity in vitro but fail to control tumour growth in vivo. Journal of Pharmaceutical Sciences, 99 (11). pp. 4642-4657. ISSN 0022-3549

Ghimire, Manish and Hodges, Lee Ann and Band, Janet and O'Mahony, Bridget and McInnes, Fiona J and Mullen, Alexander B and Stevens, Howard N E (2010) In-vitro and in-vivo erosion profiles of hydroxypropylmethylcellulose (HPMC) matrix tablets. Journal of Controlled Release, 147 (1). pp. 70-75.

McConville, Jason T. and Hodges, Lee Ann and Jones, Tamara and Band, Janet P. and O'Mahony, Bridget and Lindsay, Blythe and Ross, Alistair C. and Florence, Alastair J. and Stanley, Adrian J. and Humphrey, Michael J. and Wilson, Clive and Stevens, Howard (2009) A pharmacoscintigraphic study of three time-delayed capsule formulations in healthy male volunteers. Journal of Pharmaceutical Sciences, 98 (11). pp. 4251-4263. ISSN 0022-3549

Wilson, C. G. and O'Mahony, B. and Connolly, S. M. and Cantarini, M. V. and Farmer, M.R. and Dickinson, P.A. and Smith, R. P. and Swaisland, H.C. (2009) Do gastrointestinal transit parameters influence the pharmacokinetics of gefitinib? International Journal of Pharmaceutics, 376 (1-2). pp. 7-12. ISSN 1873-3476

Florence, A. J. and Bardin, J. and Johnston, B. and Shankland, N. and Griffin, T. A. N. and Shankland, K.; Göbel, Herbert, ed. (2009) Structure determination from powder data : Mogul and CASTEP. In: Eleventh European Powder Diffraction Conference. Zeitschrift fur Kristallografie, 30 . De Gruyter, Berlin, Germany, pp. 215-220. ISBN 9783486992588

Coxon, Geoffrey D. and Furman, Brian L. and Harvey, Alan L. and McTavish, John and Mooney, Mark H. and Arastoo, Mahmoud and Kennedy, A.R. and Tettey, J.N.A. and Waigh, R.D. (2009) Benzylguanidines and other galegine analogues inducing weight loss in mice. Journal of Medicinal Chemistry, 52 (11). pp. 3457-3463. ISSN 0022-2623

Hodges, L.A. and Connolly, S.M. and Band, J. and O'Mahony, B. and Ugurlu, T. and Turkoglu, M. and Wilson, C.G. and Stevens, H.N.E. (2009) Scintigraphic evaluation of colon targeting pectin-HPMC tablets in healthy volunteers. International Journal of Pharmaceutics, 370 (1-2). pp. 144-150. ISSN 1873-3476

Martins, D.M.S. and Middlemiss, D.S. and Pulham, C.R. and Wilson, C.C. and Weller, M.T. and Henry, P.F. and Shankland, N. and Shankland, K. (2009) Temperature- and pressure-induced proton transfer in the 1:1 adduct formed between squaric acid and 4,4'-bipyridine. Journal of the American Chemical Society, 131 (11). pp. 3884-3893. ISSN 1520-5126

Thi, M.D. and Grant, M.H. and Mullen, Alexander B. and Tettey, J.N.A. and Mackay, S.P. and Clark, Rachael L. (2009) Metabolism of two new benzodiazepine-type anti-leishmanial agents in rat hepatocytes and hepatic microsomes and their interaction with glutathione in macrophages. Journal of Pharmacy and Pharmacology, 61 (3). pp. 399-406. ISSN 0022-3573

Shankland, K. and Griffin, T.A.N. and van de Streek, J. and Cole, Jared H. and Shankland, N. and Florence, A.J. and David, W.I.F. (2009) Large-scale distributed computing for accelerated structure solution. Zeitschrift fur Kristallografie, 30. pp. 227-232. ISSN 0044-2968

Uchegbu, I.F. and Dufès, Christine M. and Kan, Pei Lee and Schätzlein, A.G.; Templeton, Nancy Smyth, ed. (2008) Polymers and dendrimers for gene delivery in gene therapy. In: Gene and cell therapy: therapeutic mechanisms and strategies 3rd ed. CRC Press, pp. 321-339. ISBN 978-0-8493-8768-5

Elouzi, Abdurrahim and Auzi, A.A. and El-Hammadi, M. and Gray, A.I. (2008) Cytotoxicity study of Ferula hermonis Boiss. Bulletin of Pharmaceutical Sciences, 31 (2). pp. 313-317. ISSN 1110-0052

Fabbiani, Francesca P.A. and Dittrich, Birger and Florence, A.J. and Gelbrich, T. and Hursthouse, M.B. and Kuhs, Werner F. and Shankland, N. and Sowa, Heidrum (2008) Crystal structures with a challenge: high-pressure crystallisation of ciprofloxacin sodium salts and their recovery to ambient pressure. CrystEngComm, 11. pp. 1396-1406. ISSN 1466-8033

Fernandes, P. and Shankland, K. and David, W.I.F. and Markvardsen, A.J. and Florence, A.J. and Shankland, N. and Leech, C.K. (2008) A differential thermal expansion approach to crystal structure determination from powder diffraction data. Journal of Applied Crystallography, 41 (6). pp. 1089-1094. ISSN 0021-8898

Florence, A.J. and Bedford, C.T. and Fabbiani, F.P.A. and Shankland, K. and Gelbrich, T. and Hursthouse, M.B. and Shankland, N. and Johnston, A. (2008) Two-dimensional similarity between forms I and II of cytenamide, a carbamazepine analogue. CrystEngComm, 10. pp. 811-813. ISSN 1466-8033

Florence, A.J. and Shankland, K. and Gelbrich, T. and Hursthouse, M.B. and Shankland, N. and Johnston, Andrea and Fernandes, P. and Leech, C.K. (2008) A catemer-to-dimer structural transformation in cyheptamide. CrystEngComm, 10. pp. 26-28. ISSN 1466-8033

Rahman, M. Mukhlesur and Gray, Alexander I. and Khondkar, Proma and Sarker, Satyajit D. (2008) Antibacterial and antifungal activities of the constituents of flemingia paniculata. Pharmaceutical Biology, 46 (5). pp. 356-359. ISSN 1388-0209

McInnes, F.J. and O'Mahony, B. and Lindsay, B. and Band, J. and Wilson, C.G. and Hodges, L.A. and Stevens, H. (2007) Nasal residence of insulin containing lyophilised nasal insert formulations, using gamma scintigraphy. European Journal of Pharmaceutical Sciences, 31 (1). pp. 25-31. ISSN 0928-0987

Rouse, J.J. and Whateley, T.L. and Thomas, M. and Eccleston, G.M. (2007) Controlled drug delivery to the lung : influence of hyaluronic acid solution conformation on its adsorption to hydrophobic drug particles. International Journal of Pharmaceutics, 330 (1-2). pp. 175-182. ISSN 1873-3476

Douglas, E. and Power, A. and Hudson, S.A. (2007) Pharmaceutical care of the patient with diabetes mellitus: pharmacists' priorities for services and education needs in Scotland. International Journal of Pharmacy Practice, 15 (1). pp. 47-52. ISSN 2042-7174

Meechan, A.J. and Henderson, C. and Bates, Catharine D. and Grant, M.H. and Tettey, J.N.A. (2006) Metabolism of troglitazone in hepatocytes isolated from experimentally induced diabetic rats. Journal of Pharmacy and Pharmacology, 58 (10). pp. 1359-1365. ISSN 0022-3573

Vu Dang, Hoang and Gray, Alexander I. and Watson, David and Bates, Catharine D. and Scholes, Peter and Eccleston, Gillain M. (2006) Composition analysis of two batches of polysorbate 60 using MS and NMR techniques. Journal of Pharmaceutical and Biomedical Analysis, 40 (5). pp. 1155-1165. ISSN 1873-264X

Stumpe, M. and Miller, C. and Morton, N.S. and Bell, G. and Watson, D.G. (2006) High-performance liquid chromatography determination of σ1-acid glycoprotein in small volumes of plasma from neonates. Journal of Chromatography B, 831 (1-2). pp. 81-84. ISSN 1570-0232

Florence, A.J. and Leech, C.K. and Shankland, N. and Shankland, K. and Johnston, A. (2006) Control and prediction of packing motifs: a rare occurrence of carbamazepine in a catemeric configuration. CrystEngComm, 8. pp. 746-747. ISSN 1466-8033

Koeberle, M. and Hughes, P.M. and Skellern, G.G. and Wilson, C.G. (2006) Pharmacokinetics and disposition of memantine in the arterially perfused bovine eye. Pharmaceutical Research, 23. pp. 2781-2798. ISSN 0724-8741

Power, A. and Douglas, E. and McGregor, A. and Hudson, S.A. (2006) Professional development of pharmaceutical care in type 2 diabetes mellitus : a multidisciplinary conceptual model. International Journal of Pharmacy Practice, 14. pp. 289-299. ISSN 2042-7174

Qu, Xioazhong and Khutoryanskiy, Vitaliy V. and Stewart, Ailsa and Rahman, Samina and Papahadjopoulos-Sternberg, Brigitte and Dufès, Christine and McCarthy, Dave and Wilson, Clive G. and Lyons, Robert and Carter, Katharine C. and Schätzlein, Andreas and Uchegbu, Ijeoma F. (2006) Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude. Biomacromolecules, 7 (12). pp. 3452-3459. ISSN 1525-7797

Yang, J. and Nie, H. and Chen, L. and Zhang, X. and Yang, F. and Xu, x. and Zhu, Y. and Yu, J. and Qi, J. (2006) Revisiting the molecular evolutionary history of shigella spp. Journal of Molecular Evolution, 64. pp. 71-79. ISSN 0022-2844

Florence, A.J. and Shankland, N. and Shankland, K. and David, W.I.F. and Pidcock, E. and Xu, X. and Johnston, A. and Kennedy, A.R. and Cox, P.J. and Evans, J.S.O. and Steele, G. and Cosgrove, S.D. and Frampton, C.S. (2005) Solving molecular crystal structures from laboratory X-ray powder diffraction data with DASH: the state of the art and challenges. Journal of Applied Crystallography, 38 (2). pp. 249-259. ISSN 0021-8898

Lewis, G.R. and Steele, G. and McBride, L. and Florence, A.J. and Kennedy, A.R. and Shankland, N. and David, W.I.F. and Teat, S.J. (2005) Hydrophobic vs hydrophilic: Ionic competition in remacemide salt structures. Crystal Growth and Design, 5 (2). pp. 427-438. ISSN 1528-7483

Hayavi, S. and Halbert, G.W. (2005) Synthetic low density lipoprotein, a novel biomimetic LiPID supplement for serum free tissue culture. Biotechnology Progress, 21 (4). pp. 1262-1268. ISSN 8756-7938

Matthews, K.H. and Stevens, H. and Aufret, A. and Humphrey, M.J. and Eccleston, G.M. (2005) Lyophilised wafers as a drug delivery system for wound healing containing methyl cellulose as a viscosity modifier. International Journal of Pharmaceutics, 289. pp. 51-62. ISSN 1873-3476

McInnes, F.J. and Thapa, P. and Baillie, A.J. and Welling, P. and Watson, D.G. and Gibson, I. and Nolan, A. and Stevens, H. (2005) In vivo evaluation of nicotine lyophilised nasal insert in sheep. International Journal of Pharmaceutics, 304 (1-2). pp. 72-82. ISSN 1873-3476

Schätzlein, Andreas G. and Zinselmeyer, Bernd H. and Elouzi, Adurrahim and Dufès, Christine and Chim, Ya Tsz A. and Roberts, Clive J. and Davies, Martyn C. and Munro, Avril and Gray, Alexander I. and Uchegbu, Ijeoma F. (2005) Preferential liver gene expression with polypropylenimine dendrimers. Journal of Controlled Release, 101 (1-3). pp. 247-258. ISSN 0168-3659

Carter, S.L. and Abbas, T. and Ram, M. and Jones, T.; Ram, M. and Patton, D and Marlow, S., eds. (2004) Breaking out of survival businesses: managing labour, growth and development in the south Asian restaurant trade. In: Managing labour in small firms. Routledge studies in small business (9). Routledge, London, United Kingdom, pp. 109-132. ISBN 041531285X

Xu, X. and Kennedy, A.R. and Florence, A.J. and Shankland, N. (2004) 4-Chlorobenzoic acid N, N-dimethylformamide solvate. Acta Crystallographica Section E: Structure Reports, 60 (11). pp. 1950-1951. ISSN 1600-5368

Khalaf, A.I. and Waigh, R.D. and Drummond, A.J. and Pringle, B. and McGroarty, I. and Skellern, G.G. and Suckling, C.J. (2004) Distamycin Analogues with Enhanced Lipophilicity: Synthesis and Antimicrobial Activity. Journal of Medicinal Chemistry, 47 (8). pp. 2133-2156. ISSN 0022-2623

McConville, Jason T and Ross, A. and Chambers, A.R. and Smith, G. and Florence, A.J. and Stevens, H. (2004) The effect of wet granulation on the erosion behaviour of an HPMC-lactose tablet, used as a rate-controlling component in a pulsatile drug delivery capsule formulation. European Journal of Pharmaceutics and Biopharmaceutics, 57 (3). pp. 541-549. ISSN 0939-6411

Graham, D. and Kennedy, A.R. and McHugh, C.J. and Smith, W.E. and David, W.I.F. and Shankland, K. and Shankland, N. (2003) The crystal structures of three primary products from the selective reduction of 2,4,6-trinitrotoluene. New Journal of Chemistry, 28. pp. 161-165. ISSN 1144-0546

Elegami, Awatif A. and Bates, Catherine and Gray, Alexander I. and Mackay, Simon P. and Skellern, Graham G. and Waigh, Roger D. (2003) Two very unusual macrocyclic flavonoids from the water lily nymphaea lotus. Phytochemistry, 63 (6). pp. 727-731. ISSN 0031-9422

Florence, A.J. and Baumgartner, B. and Weston, C. and Shankland, N. and Kennedy, A.R. and Shankland, K. and David, W.I.F. (2003) Indexing powder patterns in physical form screening: Instrumentation and data quality. Journal of Pharmaceutical Sciences, 92 (9). pp. 1930-1938. ISSN 0022-3549

Seal, D. and Beattie, T.K. and Tomlinson, A. and Fan, D. and Wong, E. (2003) Acanthamoeba keratitis. British Journal of Ophthalmology, 87 (4). pp. 516-517. ISSN 0007-1161

Bates, C.D. and Nicoll, A.E. and Mullen, A.B. and Mackenzie, F. and Thomson, A.J. and Norman, J.E. (2003) Serum profile of isosorbide mononitrate after vaginal administration in the third trimester. BJOG: An International Journal of Obstetrics and Gynaecology, 110 (1). pp. 64-67. ISSN 1470-0328

Kelly, K. and O'Mahony, B. and Lindsay, B. and Jones, T. and Grattan, T.J. and Rostami-Hodjegan, A. and Stevens, H. and Wilson, C.G. (2003) Comparison of rates of disintegration, gastric emptying, and drug absorption following administration of a new and a conventional paracetamol formulation, using γ scintigraphy. Pharmaceutical Research, 20 (10). pp. 1668-1673. ISSN 0724-8741

Koeberle, M. and Hughes, P.M. and Skellern, G.G. and Wilson, C.G. (2003) Binding of memantine to melanin: influence of type of melanin and characteristics. Pharmaceutical Research, 20 (10). pp. 1702-1709. ISSN 0724-8741

Koeberle, M. and Hughes, P.M. and Wilson, C.G. and Skellern, G.G. (2003) Development of a liquid chromatography-mass spectrometric method for the measurement of binding of memantine to different melanins. Journal of Chromatography B, 787 (2). pp. 313-322. ISSN 1570-0232

Hinshelwood, A. and McGarvie, G. and Ellis, E. (2002) Characterisation of a novel mouse liver aldo-keto reductase AKR7A5. FEBS Letters, 523 (1-3). pp. 213-218. ISSN 0014-5793

Imposimato, C. and Hoeffelman, J. and Eriksson, A. and Siew, W.H. and Pretorius, P. and Wong, P. (2002) EMI charactrization of HVAC substations : updated data and influence on immunity assessment. In: CIGRE 2002, 2002-01-01.

Oliveira, E.D.J. and Watson, D.G. and Grant, M.H. (2002) Metabolism of quercetin and kaempferol by rat hepatocytes and identification of flavonoid glycosides in plasma. Xenobiotica, 32 (4). pp. 279-287. ISSN 0049-8254

Rahman, M.M. and Gray, A. (2002) Antimicrobial constituents from the stem bark of feronia limonia. Phytochemistry, 59. pp. 73-77. ISSN 0031-9422

Shankland, N. and David, W.I.F. and Shankland, K. and Kennedy, A.R. and Frampton, C.S. and Florence, A.J. (2001) Structural transformations in zopiclone. Chemical Communications (London), 2001 (21). pp. 2204-2205. ISSN 0009-241X

Watson, D.G. and Oliveira, E.D.J. and Boyter, A.C. and Dagg, K.D. (2001) A rapid and sensitive method for the determination of the amount of theophylline in blood spots. Journal of Pharmacy and Pharmacology, 53 (3). pp. 413-416. ISSN 0022-3573

Florence, A.J. and Kennedy, A.R. and Shankland, N. and Wright, E. and Al-Rubayi, A. (2000) Norfloxacin dihydrate. Acta Crystallographica Section C: Crystal Structure Communications, 56 (11). pp. 1372-1373. ISSN 0108-2701

Kennedy, A.R. and Skellern, G.G. and Pfirrmann, R.W. and Smail, G.A. and Shankland, N. and Florence, A.J. (1999) Two new compounds by reaction of taurolidine with methylene glycol. Acta Crystallographica Section C: Crystal Structure Communications, 55 (2). pp. 232-234. ISSN 0108-2701

Lockerbie, N.A. and Xu, X. and Veryaskin, A.V. (1996) Gravitational modelling of the test masses for STEP and LISA. Classical and Quantum Gravity, 13 (11A). A91-A95. ISSN 1361-6382

Lockerbie, N.A. and Veryaskin, A.V. and Xu, X. (1996) Analytical evaluation of short-range forces in cylindrical geometry. Journal of Physics A: Mathematical and Theoretical, 29 (15). pp. 4649-4663. ISSN 0305-4470

Lockerbie, N.A. and Xu, X. and Veryaskin, A.V. (1996) The gravitational coupling between longitudinal segments of a hollow cylinder and an arbitrary gravitational source: Relevance to the STEP experiment. Classical and Quantum Gravity, 13 (8). pp. 2041-2059. ISSN 1361-6382

Xu, X. and Lockerbie, N.A. (1996) Forward modelling of geophysical survey data using cylindrical elemental volumes. Nuovo Cimento B, 111 (4). pp. 497-506. ISSN 0369-3554

Lockerbie, N.A. and Xu, X. and Veryaskin, A.V. (1995) Spherical harmonic representation of the gravitational coupling between a truncated sector of a hollow cylinder and an arbitrary gravitational source: Relevance to the STEP experiment. General Relativity and Gravitation, 27 (11). pp. 1215-1229. ISSN 0001-7701

Lockerbie, N.A. and Xu, X. and Veryaskin, A.V. (1995) Optimization of the geometry for dipole-dipole and dipole-monopole experiments, using the gravitational interaction between a point-source and a finite cylinder. Nuovo Cimento B, 110 (10). pp. 1183-1195. ISSN 0369-3554

Lockerbie, N.A. and Xu, X. and Veryaskin, A.V. and Hosey, M.A. (1994) Optimization of immunity to helium tidal influences for the STEP experiment test masses. Classical and Quantum Gravity, 11 (6). pp. 1575-1590. ISSN 1361-6382

Lockerbie, N.A. and Veryaskin, A.V. and Xu, X. (1993) Differential gravitational coupling between cylindrically-symmetric, concentric test masses and an arbitrary gravitational source: relevance to the STEP experiment. Classical and Quantum Gravity, 10 (11). pp. 2419-2430. ISSN 1361-6382