Items where subject is "Genetics"

2021

Dasgupta, Asish and Chen, Kuang-Hueih and Lima, Patricia D.A. and Mewburn, Jeffrey and Wu, Danchen and Al-Qazazi, Ruaa and Jones, Oliver and Tian, Lian and Potus, Francois and Bonnet, Sebastien and Archer, Stephen L. (2021) PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension. FASEB Journal, 35 (8). e21771. ISSN 0892-6638

Huszar, Tunde I. and Gettings, Katherine B. and Vallone, Peter M. (2021) An introductory overview of open-source and commercial software options for the analysis of forensic sequencing data. Genes, 12 (11). 1739. ISSN 2073-4425

McDonald, Iain (2021) Improved models of coalescence ages of Y-DNA haplogroups. Genes, 12 (6). 862. ISSN 2073-4425

Schorn, Michelle A. and Verhoeven, Stefan and Ridder, Lars and Huber, Florian and Acharya, Deepa D. and Aksenov, Alexander A. and Aleti, Gajender and Moghaddam, Jamshid Amiri and Aron, Allegra T. and Aziz, Saefuddin and Bauermeister, Anelize and Bauman, Katherine D. and Baunach, Martin and Beemelmanns, Christine and Beman, J. Michael and Berlanga-Clavero, María Victoria and Blacutt, Alex A. and Bode, Helge B. and Boullie, Anne and Brejnrod, Asker and Bugni, Tim S. and Calteau, Alexandra and Cao, Liu and Carrión, Víctor J. and Castelo-Branco, Raquel and Chanana, Shaurya and Chase, Alexander B. and Chevrette, Marc G. and Costa-Lotufo, Leticia V. and Crawford, Jason M. and Currie, Cameron R. and Cuypers, Bart and Dang, Tam and de Rond, Tristan and Demko, Alyssa M. and Dittmann, Elke and Du, Chao and Drozd, Christopher and Dujardin, Jean-Claude and Dutton, Rachel J. and Edlund, Anna and Fewer, David P. and Garg, Neha and Gauglitz, Julia M. and Gentry, Emily C. and Gerwick, Lena and Glukhov, Evgenia and Gross, Harald and Gugger, Muriel and Guillén Matus, Dulce G. and Helfrich, Eric J. N. and Hempel, Benjamin-Florian and Hur, Jae-Seoun and Iorio, Marianna and Jensen, Paul R. and Kang, Kyo Bin and Kaysser, Leonard and Kelleher, Neil L. and Kim, Chung Sub and Kim, Ki Hyun and Koester, Irina and König, Gabriele M. and Leao, Tiago and Lee, Seoung Rak and Lee, Yi-Yuan and Li, Xuanji and Little, Jessica C. and Maloney, Katherine N. and Männle, Daniel and Martin H., Christian and McAvoy, Andrew C. and Metcalf, Willam W. and Mohimani, Hosein and Molina-Santiago, Carlos and Moore, Bradley S. and Mullowney, Michael W. and Muskat, Mitchell and Nothias, Louis-Félix and O'Neill, Ellis C. and Parkinson, Elizabeth I. and Petras, Daniel and Piel, Jörn and Pierce, Emily C. and Pires, Karine and Reher, Raphael and Romero, Diego and Roper, M. Caroline and Rust, Michael and Saad, Hamada and Saenz, Carmen and Sanchez, Laura M. and Sørensen, Søren Johannes and Sosio, Margherita and Süssmuth, Roderich D. and Sweeney, Douglas and Tahlan, Kapil and Thomson, Regan J. and Tobias, Nicholas J. and Trindade-Silva, Amaro E. and van Wezel, Gilles P. and Wang, Mingxun and Weldon, Kelly C. and Zhang, Fan and Ziemert, Nadine and Duncan, Katherine R. and Crüsemann, Max and Rogers, Simon and Dorrestein, Pieter C. and Medema, Marnix H. and van der Hooft, Justin J. J. (2021) A community resource for paired genomic and metabolomic data mining. Nature Chemical Biology, 17 (4). pp. 363-368. ISSN 1552-4450

2020

Holmes, Ashleigh and Pritchard, Leighton and Hedley, Peter E. and Morris, Jenny and McAteer, Sean P. and Gally, David L. and Holden, Nicola J. (2020) A high-throughput genomic screen identifies a role for the plasmid-borne type II secretion system of Escherichia coli O157:H7 (Sakai) in plant-microbe interactions. Genomics, 112 (6). pp. 4242-4253. ISSN 1089-8646

2018

Padroni, Giacomo and Parkinson, John A. and Fox, Keith R. and Burley, Glenn A. (2018) Structural basis of DNA duplex distortion induced by thiazole-containing hairpin polyamides. Nucleic Acids Research, 46 (1). pp. 42-53. ISSN 0305-1048

2017

Alshehhi, Suaad and McCallum, Nicola A. and Haddrill, Penelope R. (2017) Quantification of RNA degradation of blood-specific markers to indicate the age of bloodstains. Forensic Science International: Genetics Supplement Series, 6. e453-e455. ISSN 1875-1768

Grosse-Kock, Steffan and Kolodkina, Valentina and Schwalbe, Edward C. and Blom, Jochen and Burkovski, Andreas and Hoskisson, Paul A. and Brisse, Sylvain and Smith, Darren and Sutcliffe, Iain C. and Titov, Leonid and Sangal, Vartul (2017) Genomic analysis of endemic clones of toxigenic and non-toxigenic Corynebacterium diphtheriae in Belarus during and after the major epidemic in 1990s. BMC Genomics, 18. ISSN 1471-2164

Jackson, Benjamin C. and Campos, José L. and Haddrill, Penelope R. and Charlesworth, Brian and Zeng, Kai (2017) Variation in the intensity of selection on codon bias over time causes contrasting patterns of base composition evolution in Drosophila. Genome Biology and Evolution, 9 (1). pp. 102-123. ISSN 1759-6653

Schniete, Jana K. and Salih, Talal S. and Algora-Gallardo, Lis and Santos, Tiago and Filgueira-Martinez, Sara and Herron, Paul R. (2017) Draft genome sequence of Streptomyces phaeoluteigriseus DSM41896. Genome Announcements, 5 (21). e00371-17. ISSN 2169-8287

2015

Bergman, Casey M. and Haddrill, Penelope R (2015) Strain-specific and pooled genome sequences for populations of Drosophila melanogaster from three continents. F1000Research, 4 (31).

Freschi, Luca and Jeukens, Julie and Kukavica-Ibrulj, Irena and Boyle, Brian and Dupont, Marie-Josée and Laroche, Jérôme and Larose, Stéphane and Maaroufi, Halim and Fothergill, Joanne L. and Moores, Matthew and Winsor, Geoffrey L. and Aaron, Shawn D. and Barbeau, Jean and Bell, Scott C. and Burns, Jane L. and Camara, Miguel and Cantin, André and Charette, Steve J. and Dewar, Ken and Déziel, Éric and Grimwood, Keith and Hancock, Robert E. W. and Harrison, Joe J. and Heeb, Stephan and Jelsbak, Lars and Jia, Baofeng and Kenna, Dervla T. and Kidd, Timothy J. and Klockgether, Jens and Lam, Joseph S. and Lamont, Iain L. and Lewenza, Shawn and Loman, Nick and Malouin, François and Manos, Jim and McArthur, Andrew G. and McKeown, Josie and Milot, Julie and Naghra, Hardeep and Nguyen, Dao and Pereira, Sheldon K. and Perron, Gabriel G. and Pirnay, Jean-Paul and Rainey, Paul B. and Rousseau, Simon and Santos, Pedro M. and Stephenson, Anne and Taylor, Véronique and Turton, Jane F. and Waglechner, Nicholas and Williams, Paul and Thrane, Sandra W. and Wright, Gerard D. and Brinkman, Fiona S. L. and Tucker, Nicholas P. and Tümmler, Burkhard and Winstanley, Craig and Levesque, Roger C. (2015) Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium. Frontiers in Microbiology, 6. 1036. ISSN 1664-302X

Houslay, Miles (2015) Hypertension linked to PDE3A activation. Nature Genetics, 47 (6). pp. 562-563. ISSN 1061-4036

Simpson, Nuala H and Ceroni, Fabiola and Reader, Rose H and Covill, Laura E and Knight, Julian C and Hennessy, Elizabeth R and Bolton, Patrick F and Conti-Ramsden, Gina and O'Hare, Anne and Baird, Gillian and Fisher, Simon E and Newbury, Dianne F and Nudel, R and Monaco, AP and Simonoff, E and Bolton, PF and Pickles, A and Slonims, V and Dworzynski, K and Everitt, A and Clark, A and Watson, J and Seckl, J and Cowie, H and Cohen, W and Nasir, J. and Bishop, DVM and Simkin, Z (2015) Genome-wide analysis identifies a role for common copy number variants in specific language impairment. European Journal of Human Genetics, 23 (10). pp. 1370-1377. ISSN 1018-4813

Tate, Rothwelle and Rotondo, Dino and Davidson, Jillian (2015) Regulation of lipid metabolism by microRNAs. Current Opinion in Lipidology, 26 (3). pp. 243-244. ISSN 0957-9672

Villanueva, Pía and Nudel, Ron and Hoischen, Alexander and Fernández, María Angélica and Simpson, Nuala H. and Gilissen, Christian and Reader, Rose H. and Jara, Lillian and Echeverry, Maria Magdalena and Francks, Clyde and Baird, Gillian and Conti-Ramsden, Gina and O’Hare, Anne and Bolton, Patrick F. and Hennessy, Elizabeth R. and Palomino, Hernán and Carvajal-Carmona, Luis and Veltman, Joris A. and Cazier, Jean Baptiste and De Barbieri, Zulema and Fisher, Simon E. and Newbury, Dianne F. and Slonims, V. and Clark, Ann and Watson, Jocelynne and Simonoff, E. and Pickles, A. and Everitt, A. and Seckl, J. and Cowie, H. and Cohen, W. and Nasir, J. and Bishop, D. V M and Simkin, Z. (2015) Exome sequencing in an admixed isolated population indicates NFXL1 variants confer a risk for specific language impairment. PLOS Genetics, 11 (3). e1004925. ISSN 1553-7390

2014

McGinty, Sean (2014) A decade of modelling drug release from arterial stents. Mathematical Biosciences, 257. pp. 80-90. ISSN 0025-5564

Morris, B.J. and Pratt, J.A. (2014) Novel treatment strategies for schizophrenia from improved understanding of genetic risk. Clinical Genetics, 86 (5). pp. 401-411. ISSN 0009-9163

2013

Campos, Jose L and Zeng, Kai and Parker, Darren J and Charlesworth, Brian and Haddrill, Penelope R (2013) Codon usage bias and effective population sizes on the X chromosome versus the autosomes in Drosophila melanogaster. Molecular Biology and Evolution, 30 (4). pp. 811-823.

2012

Campos, José L and Charlesworth, Brian and Haddrill, Penelope R (2012) Molecular evolution in nonrecombining regions of the Drosophila melanogaster genome. Genome Biology and Evolution, 4 (3). pp. 278-288.

2011

Nowell, Reuben W and Charlesworth, Brian and Haddrill, Penelope R (2011) Ancestral polymorphisms in Drosophila pseudoobscura and Drosophila miranda. Genetics Research, 93 (4). pp. 255-263.

Thanakiatkrai, Phuvadol and Welch, Lindsey (2011) Evaluation of nucleosome forming potentials (NFPs) of forensically important STRs. Forensic Science International: Genetics, 5 (4). pp. 285-290. ISSN 1872-4973

2010

Haddrill, Penelope R and Loewe, Laurence and Charlesworth, Brian (2010) Estimating the parameters of selection on nonsynonymous mutations in Drosophila pseudoobscura and D. miranda. Genetics, 185 (4). pp. 1381-1396.

Koppu, Swati and Oh, Yew Jinn and Edrada-Ebel, R. and Blatchford, David R. and Tetley, L. and Tate, R. and Dufès, Christine (2010) Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA. Journal of Controlled Release, 143 (2). pp. 215-221. ISSN 0168-3659

Tucker, Nick and Ghosh, T. and Bush, M. and Zhang, X. and Dixon, Ray (2010) Essential roles of three enhancer sites in sigma-54-dependent transcription by the nitric oxide sensing regulatory protein NorR. Nucleic Acids Research, 38 (4). pp. 1182-1194. ISSN 0305-1048

2009

Boonseub, Sansook and Tobe, Shanan S. and Linacre, Adrian M.T. (2009) The use of mitochondrial DNA genes to identify closely related avian species. Forensic Science International: Genetics Supplement Series, 2 (1). pp. 275-277. ISSN 1875-1768

Scottish Government (Funder); Fraser, Jim. (2009) Acquisition and retention of DNA and fingerprint data in Scotland. [Report]

Hoskisson, P. and Rigali, S.; Laskin, A.I. and Sariaslani, S. and Gadd, G.M., eds. (2009) Variation in form and function: the helix-turn-helix regulators of the GntR superfamily. In: Advances in Applied Microbiology. Advances in Applied Microbiology, 69 . Elsevier, pp. 1-22. ISBN 9780123748249

Hunsicker, A. and Steber, M. and Mayer, G. and Meitert, J. and Klotzsche, M. and Blind, M. and Hillen, W. and Berens, C. (2009) An RNA Aptamer that Induces Transcription. Chemistry and Biology, 16. pp. 173-180. ISSN 1074-5521

Jayapal, P. and Mayer, G. and Heckel, A. and Wennmohs, F. (2009) Structure-Activity Relationships of a Caged Thrombin-Binding DNA Aptamer: Insight gained from molecular dynamics simulation studies. Journal of Structural Biology, 166 (3). pp. 241-250. ISSN 1047-8477

Kitpipit, Thitika and Linacre, Adrian and Tobe, Shanan S. (2009) Tiger species identification based on molecular approach. Forensic Science International: Genetics Supplement Series, 2 (1). pp. 310-312. ISSN 1875-1768

Knight, Helen M and Pickard, Benjamin S and Maclean, Alan and Malloy, Mary P and Soares, Dinesh C and McRae, Allan F and Condie, Alison and White, Angela and Hawkins, William and McGhee, Kevin and van Beck, Margaret and MacIntyre, Donald J and Starr, John M and Deary, Ian J and Visscher, Peter M and Porteous, David J and Cannon, Ronald E and St Clair, David and Muir, Walter J and Blackwood, Douglas H R (2009) A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression. American Journal of Human Genetics, 85 (6). pp. 833-846. ISSN 0002-9297

Mayer, G. and Faulhammer, D. and Grättinger, M. and Fessele, S. and Blind, M. (2009) A RNA-based approach towards small molecule inhibitors. Chembiochem, 10 (12). pp. 1993-1996. ISSN 1439-4227

Tobe, Shanan S. and Kitchener, Andrew and Linacre, Adrian (2009) Cytochrome b or cytochrome c oxidase subunit I for mammalian species identification—An answer to the debate. Forensic Science International: Genetics Supplement Series, 2 (1). pp. 306-307. ISSN 1875-1768

2008

Dijkhuizen, L. and Goodfellow, Mike and Hoskisson, P. and Sutcliffe, I. (2008) Actinomycetologists: a vibrant and strong scientific community. Papers from the 14th International Symposium on the Biology of Actinomycetes. Antonie van Leeuwenhoek, 94 (1). pp. 1-2. ISSN 0003-6072

Lee, J.C.I. and Tsai, L.C. and Huang, M.T. and Jhuang, J.A. and Yao, C.T. and Chin, S.C. and Wang, L.C. and Linacre, A.M.T. (2008) A novel strategy for avian species identification by cytochrome B gene. Electrophoresis, 29 (11). pp. 2413-2418. ISSN 0173-0835

Stone, J.L. and O'Donovan, M.C. and Gurling, H. and Kirov, G.K. and Blackwood, D.H.R. and Corvin, A. and Craddock, N.J. and Gill, M. and Pickard, B.S., The International Schizophrenia Consortium (2008) Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature, 455 (7210). pp. 237-241. ISSN 0028-0836

Tobe, Shanan S. and Linacre, Adrian (2008) Quantification of trace amounts of human and non-human mitochondrial DNA (mtDNA) using SYBR Green and real time PCR. Forensic Science International: Genetics Supplement Series, 1 (1). pp. 71-73. ISSN 1875-1768

Tobe, Shanan S. and Linacre, Adrian (2008) A method to identify a large number of mammalian species in the UK from trace samples and mixtures without the use of sequencing. Forensic Science International: Genetics Supplement Series, 1 (1). pp. 625-627. ISSN 1875-1768

Tobe, Shanan S. and Linacre, Adrian M.T. (2008) A technique for the quantification of human and non-human mammalian mitochondrial DNA copy number in forensic and other mixtures. Forensic Science International: Genetics, 2 (4). pp. 249-256. ISSN 1872-4973

Uchegbu, I.F. and Dufès, Christine M. and Kan, Pei Lee and Schätzlein, A.G.; Templeton, Nancy Smyth, ed. (2008) Polymers and dendrimers for gene delivery in gene therapy. In: Gene and cell therapy: therapeutic mechanisms and strategies 3rd ed. CRC Press, pp. 321-339. ISBN 978-0-8493-8768-5

Vicoso, Beatriz and Haddrill, Penelope R and Charlesworth, Brian (2008) A multispecies approach for comparing sequence evolution of X-linked and autosomal sites in Drosophila. Genetics Research, 90 (5). pp. 421-431.

2007

Haddrill, Penelope R and Halligan, Daniel L and Tomaras, Dimitris and Charlesworth, Brian (2007) Reduced efficacy of selection in regions of the Drosophila genome that lack crossing over. Genome Biology, 8 (2). R18.

Pickard, B. S. and Thomson, P. A. and Christoforou, A. and Evans, K. L. and Morris, S. W. and Porteous, D. J. and Blackwood, D. H. and Muir, W. J. (2007) The PDE4B gene confers sex-specific protection against schizophrenia. Psychiatric Genetics, 17. pp. 129-133. ISSN 0955-8829

2006

Adie, E. A. and Adams, R. R. and Evans, K. L. and Porteous, D. J. and Pickard, B. S. (2006) SUSPECTS : enabling fast and effective prioritization of positional candidates. Bioinformatics, 22 (6). pp. 773-774. ISSN 1367-4803

Muir, Walter J. and Pickard, Benjamin S. and Blackwood, Douglas H.R. (2006) Chromosomal abnormalities and psychosis. British Journal of Psychiatry, 188 (6). pp. 501-503. ISSN 0007-1250

Nasir, Jamal and Frima, Nafsika and Pickard, Ben and Malloy, M. Pat and Zhan, Lingping and Grunewald, Richard (2006) Unbalanced whole arm translocation resulting in loss of 18p in dystonia. Movement Disorders, 21 (6). pp. 859-863. ISSN 0885-3185

Pickard, Benjamin S. and Pieper, Andrew A. and Porteous, David J. and Blackwood, Douglas H. and Muir, Walter J. (2006) The NPAS3 gene--emerging evidence for a role in psychiatric illness. Annals of medicine, 38 (6). pp. 439-448. ISSN 1365-2060

Richards, Thomas A and Dacks, Joel B and Campbell, Samantha A and Blanchard, Jeffrey L and Foster, Peter G and McLeod, Rima and Roberts, Craig W (2006) Evolutionary origins of the eukaryotic shikimate pathway : gene fusions, horizontal gene transfer, and endosymbiotic replacements. Eukaryotic cell, 5 (9). pp. 1517-1531. ISSN 1535-9778

2005

Haddrill, Penelope R and Charlesworth, Brian and Halligan, Daniel L and Andolfatto, Peter (2005) Patterns of intron sequence evolution in Drosophila are dependent upon length and GC content. Genome Biology, 6 (8). R67.

Haddrill, Penelope R and Thornton, Kevin R and Charlesworth, Brian and Andolfatto, Peter (2005) Multilocus patterns of nucleotide variability and the demographic and selection history of drosophila melanogaster populations. Genome Research, 15 (6). pp. 790-799. ISSN 1088-9051

Millar, J. Kirsty and Pickard, Benjamin S. and Mackie, Shaun and James, Rachel and Christie, Sheila and Buchanan, Sebastienne R. and Malloy, M. Pat and Chubb, Jennifer E. and Huston, Elaine and Baillie, George S. and Thomson, Pippa A. and Hill, Elaine V. and Brandon, Nicholas J. and Rain, Jean-Christophe and Camargo, L. Miguel and Whiting, Paul J. and Houslay, Miles D. and Blackwood, Douglas H. R. and Muir, Walter J. and Porteous, David J. (2005) DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science, 310 (5751). pp. 1187-1191. ISSN 1095-9203

Pickard, Ben S. and Malloy, M. Pat and Clark, Leanne and Lehellard, Stéphanie and Ewald, Henrik L. and Mors, Ole and Porteous, David J. and Blackwood, Douglas H. R. and Muir, Walter J. (2005) Candidate psychiatric illness genes identified in patients with pericentric inversions of chromosome 18. Psychiatric Genetics, 15 (1). pp. 37-44. ISSN 0955-8829

2004

Pickard, Ben S and Hollox, Edward J and Malloy, M Pat and Porteous, David J and Blackwood, Douglas HR and Armour, John AL and Muir, Walter J (2004) A 4q35.2 subtelomeric deletion identified in a screen of patients with co-morbid psychiatric illness and mental retardation. BMC Medical Genetics, 5 (21). 21. ISSN 1471-2350

2003

Porteous, D.J. and Evans, K.L. and Millar, J.K. and Pickard, B.S. and Thomson, P.A. and James, R. and MacGregor, S. and Wray, N.R. and Visscher, P.M. and Muir, W.J. and Blackwood, D.H. (2003) Genetics of schizophrenia and bipolar affective disorder: strategies to identify candidate genes. Cold Spring Harbor symposia on quantitative biology, 68. pp. 383-394. ISSN 1943-4456

2001

Valenza-Schaerly, Pascale and Pickard, Benjamin and Walter, Jörn and Jung, Martin and Pourcel, Lucille and Reik, Wolf and Gauguier, Dominique and Vergnaud, Gilles and Pourcel, Christine (2001) A dominant modifier of transgene methylation is mapped by QTL analysis to mouse chromosome 13. Genome Research, 11 (3). pp. 382-388. ISSN 1088-9051

1998

Constância, Miguel and Pickard, Benjamin and Kelsey, Gavin and Reik, Wolf (1998) Imprinting mechanisms. Genome Research, 8 (9). pp. 881-900. ISSN 1088-9051

1993

Echevarria, F.A.M. and Gettinby, G. and Hazelwood, S. (1993) Model predictions for anthelmintic resistance amongst Haemonchus contortus populations in southern Brazil. Veterinary Parasitology, 47 (3-4). pp. 315-325. ISSN 0304-4017

1991

Ducancel, F. and Rowan, E.G. and Cassar, E. and Harvey, A.L. and Menez, A. and Boulain, J.C. (1991) Amino acid sequence of a muscarinic toxin deduced from the cDNA nucleotide sequence. Toxicon, 29 (4-5). pp. 516-520. ISSN 1879-3150

1990

Chwetzoff, S. and Mollier, P. and Bouet, F. and Rowan, E.G. and Harvey, A.L. and Menez, A. (1990) On the purification of notexin: isolation of a single amino acid variant from the venom of Notechis scutatus scutatus. FEBS Letters, 261 (2). pp. 226-230. ISSN 0014-5793

Rowan, E.G. and Ducancel, F. and Doljansky, Y. and Harvey, A.L. and Boulain, J.C. and Menez, A. (1990) Nucleotide-sequence encoding a synergistic-like protein from the venom glands of Dendroaspis angusticeps. Nucleic Acids Research, 18 (6). p. 1639. ISSN 0305-1048

Takasaki, C. and Sugama, A. and Yanagita, A. and Tamiya, N. and Rowan, E.G. and Harvey, A.L. (1990) Effects of chemical modifications of Pa-11, a phospholipase A2 from the venom of Australian king brown snake (Pseudechis australis), on its biological activities. Toxicon, 28 (1). pp. 107-117. ISSN 1879-3150

1988

Norrie, Kenneth; Bruce, N and Mitchell, A and Priestley, K, eds. (1988) Genetic knowledge and the law. In: Truth and the Child. Family Care, Edinburgh, Edinburgh. ISBN 0950811750