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2025

Lee, Yunji and McAllister, Katie and Lee, Hwa-Rim and Jung, Sungjune and Murphy, Fiona (2025) Evaluation of a bioprinted 3D airway tissue model for toxicity testing of nanomaterials; pathway to integration into a tiered testing strategy for hazard assessment to support safety-by-design. Nano Today, 61. 102655. ISSN 1878-044X

Fraser, Roma and Campbell, Keira and Pokorski, Pawel and Mackinnon, Eve and McAllister, Katie and Neves, Karla B. and Murphy, Fiona (2025) Humanising nanotoxicology : replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard. Frontiers in Bioengineering and Biotechnology, 13. 1526808. ISSN 2296-4185

Jaurand, Marie-Claude and Murphy, Fiona and Felley-Bosco, Emanuela (2025) Asbestos and disease genomics : is mesothelioma a genomic paradigm? Frontiers in Toxicology, 6. 1536344. ISSN 2673-3080

Brunelli, A. and Serrano-Lotina, A. and Bañares, M. A. and Alcolea-Rodriguez, V. and Blosi, M. and Costa, A. and Ortelli, S. and Peijnenburg, W. and Fito, C. and Fernandez, E. G. and Hermosilla, J. S. and Soeteman-Hernández, L. G. and Garmendia Aguirre, I. and Rauscher, H. and Murphy, F. and Stone, V. and Balbuena, J. and Cormano, J. M. L. and Pizzol, L. and Hristozov, D. and Marcomini, A. and Badetti, E. (2025) Safe-by-design assessment of an SiO2@ZnO multi-component nanomaterial used in construction. Environmental Science: Nano, 12 (1). pp. 762-776. ISSN 2051-8153

2024

Wiejak, Jolanta and Murphy, Fiona A. and Barker, Graeme and Maffia, Pasquale and Yarwood, Stephen J. (2024) Non-cyclic nucleotide EPAC1 activators suppress lipopolysaccharide-regulated gene expression, signalling and intracellular communication in differentiated macrophage-like THP-1 cells. Cellular Signalling, 124. 111444. ISSN 1873-3913

Watts, Emily and Willison, Joseph and Arienti, Simone and Sadiku, Pranvera and Coelho, Patricia and Sanchez-Garcia, Manuel and Zhang, Ailiang and Murphy, Fiona and Dickinson, Rebecca and Mirchandani, Ananda and Morrison, Tyler and Lewis, Amy and Vermaelen, Wesley and Ghesquiere, Bart and Carmeliet, Peter and Mazzone, Massimilliano and Maxwell, Patrick and Pugh, Christopher and Dockrell, David and Whyte, Moira and Walmsley, Sarah (2024) Differential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function. Wellcome Open Research, 8. 569. ISSN 2398-502X

Di Battista, Veronica and Sanchez-Lievanos, Karla R. and Jeliazkova, Nina and Murphy, Fiona and Tsiliki, Georgia and Zabeo, Alex and Gajewicz-Skretna, Agnieszka and Mikołajczyk, Alicja and Hristozov, Danail and Stone, Vicki and Schmid, Otmar and Hunt, Neil and Oomen, Agnes G. and Wohlleben, Wendel (2024) Similarity of multicomponent nanomaterials in a safer-by-design context : the case of core–shell quantum dots. Environmental Science: Nano, 11 (3). pp. 924-941. ISSN 2051-8153

2023

Wiejak, Jolanta and Murphy, Fiona A. and Maffia, Pasquale and Yarwood, Stephen J. (2023) Vascular smooth muscle cells enhance immune/vascular interplay in a 3-cell model of vascular inflammation. Scientific Reports, 13. 15889. ISSN 2045-2322

Murphy, Fiona A. and Johnston, Helinor J. and Dekkers, Susan and Bleeker, Eric A.J. and Oomen, Agnes G. and Fernandes, Teresa F. and Rasmussen, Kirsten and Jantunen, Paula and Rauscher, Hubert and Hunt, Neil and di Cristo, Luisana and Braakhuis, Hedwig M. and Haase, Andrea and Hristozov, Danail and Wohlleben, Wendel and Sabella, Stefania and Stone, Vicki (2023) How to formulate hypotheses and IATAs to support grouping and read-across of nanoforms. Altex, 40 (1). pp. 125-140. ISSN 1868-596X

2022

Murphy, Fiona and Jacobsen, Nicklas Raun and Di Ianni, Emilio and Johnston, Helinor and Braakhuis, Hedwig and Peijnenburg, Willie and Oomen, Agnes and Fernandes, Teresa and Stone, Vicki (2022) Grouping MWCNTs based on their similar potential to cause pulmonary hazard after inhalation : a case-study. Particle and Fibre Toxicology, 19 (1). 50.

Di Cristo, Luisana and Ude, Victor C. and Tsiliki, Georgia and Tatulli, Giuseppina and Romaldini, Alessio and Murphy, Fiona and Wohlleben, Wendel and Oomen, Agnes G. and Pompa, Pier P. and Arts, Josje and Stone, Vicki and Sabella, Stefania (2022) Grouping of orally ingested silica nanomaterials via use of an integrated approach to testing and assessment to streamline risk assessment. Particle and Fibre Toxicology, 19 (1). p. 68. 68.

Boyles, Matthew and Murphy, Fiona and Mueller, William and Wohlleben, Wendel and Jacobsen, Nicklas Raun and Braakhuis, Hedwig and Giusti, Anna and Stone, Vicki (2022) Development of a standard operating procedure for the DCFH2-DA acellular assessment of reactive oxygen species produced by nanomaterials. Toxicology Mechanisms and Methods, 32 (6). pp. 439-452. ISSN 1537-6524

Powell, L. G. and Gillies, S. and Fernandes, T. F. and Murphy, F. and Giubilato, E. and Cazzagon, V. and Hristozov, D. and Pizzol, L. and Blosi, M. and Costa, A. L. and Prina-Mello, A. and Bouwmeester, H. and Sarimveis, H. and Janer, G. and Stone, V. (2022) Developing integrated approaches for testing and assessment (IATAs) in order to support nanomaterial safety. Nanotoxicology, 16 (4). pp. 484-499. ISSN 1743-5404

Mirchandani, Ananda S. and Jenkins, Stephen J. and Bain, Calum C. and Sanchez-Garcia, Manuel A. and Lawson, Hannah and Coelho, Patricia and Murphy, Fiona and Griffith, David M. and Zhang, Ailiang and Morrison, Tyler and Ly, Tony and Arienti, Simone and Sadiku, Pranvera and Watts, Emily R. and Dickinson, Rebecca S. and Reyes, Leila and Cooper, George and Clark, Sarah and Lewis, David and Kelly, Van and Spanos, Christos and Musgrave, Kathryn M. and Delaney, Liam and Harper, Isla and Scott, Jonathan and Parkinson, Nicholas J. and Rostron, Anthony J. and Baillie, J. Kenneth and Clohisey, Sara and Pridans, Clare and Campana, Lara and Lewis, Philip Starkey and Simpson, A. John and Dockrell, David H. and Schwarze, Jürgen and Hirani, Nikhil and Ratcliffe, Peter J. and Pugh, Christopher W. and Kranc, Kamil and Forbes, Stuart J. and Whyte, Moira K.B. and Walmsley, Sarah R. (2022) Author correction : Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation. Nature Immunology, 23. 1394. ISSN 1529-2908

Mirchandani, Ananda S. and Jenkins, Stephen J. and Bain, Calum C. and Sanchez-Garcia, Manuel A. and Lawson, Hannah and Coelho, Patricia and Murphy, Fiona and Griffith, David M. and Zhang, Ailiang and Morrison, Tyler and Ly, Tony and Arienti, Simone and Sadiku, Pranvera and Watts, Emily R. and Dickinson, Rebecca S. and Reyes, Leila and Cooper, George and Clark, Sarah and Lewis, David and Kelly, Van and Spanos, Christos and Musgrave, Kathryn M. and Delaney, Liam and Harper, Isla and Scott, Jonathan and Parkinson, Nicholas J. and Rostron, Anthony J. and Baillie, J. Kenneth and Clohisey, Sara and Pridans, Clare and Campana, Lara and Lewis, Philip Starkey and Simpson, A. John and Dockrell, David H. and Schwarze, Jürgen and Hirani, Nikhil and Ratcliffe, Peter J. and Pugh, Christopher W. and Kranc, Kamil and Forbes, Stuart J. and Whyte, Moira K.B. and Walmsley, Sarah R. (2022) Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation. Nature Immunology, 23 (6). pp. 927-939. ISSN 1529-2908

Di Cristo, Luisana and Janer, Gemma and Dekkers, Susan and Boyles, Matthew and Giusti, Anna and Keller, Johannes G. and Wohlleben, Wendel and Braakhuis, Hedwig and Ma-Hock, Lan and Oomen, Agnes G. and Haase, Andrea and Stone, Vicki and Murphy, Fiona and Johnston, Helinor J. and Sabella, Stefania (2022) Integrated approaches to testing and assessment for grouping nanomaterials following dermal exposure. Nanotoxicology, 16 (3). pp. 310-332. ISSN 1743-5404

Verdon, Rachel and Stone, Vicki and Murphy, Fiona and Christopher, Emily and Johnston, Helinor and Doak, Shareen and Vogel, Ulla and Haase, Andrea and Kermanizadeh, Ali (2022) The application of existing genotoxicity methodologies for grouping of nanomaterials : towards an integrated approach to testing and assessment. Particle and Fibre Toxicology, 19 (1). 32.

Ag Seleci, Didem and Tsiliki, Georgia and Werle, Kai and Elam, Derek A. and Okpowe, Omena and Seidel, Karsten and Bi, Xiangyu and Westerhoff, Paul and Innes, Emma and Boyles, Matthew and Miller, Mark and Giusti, Anna and Murphy, Fiona and Haase, Andrea and Stone, Vicki and Wohlleben, Wendel (2022) Determining nanoform similarity via assessment of surface reactivity by abiotic and in vitro assays. NanoImpact, 26. 100390. ISSN 2452-0748

2021

Di Cristo, Luisana and Oomen, Agnes G. and Dekkers, Susan and Moore, Colin and Rocchia, Walter and Murphy, Fiona and Johnston, Helinor J. and Janer, Gemma and Haase, Andrea and Stone, Vicki and Sabella, Stefania (2021) Grouping hypotheses and an integrated approach to testing and assessment of nanomaterials following oral ingestion. Nanomaterials, 11 (10). 2623. ISSN 2079-4991

Braakhuis, Hedwig M. and Murphy, Fiona and Ma-Hock, Lan and Dekkers, Susan and Keller, Johannes and Oomen, Agnes G. and Stone, Vicki (2021) An integrated approach to testing and assessment to support grouping and read-across of nanomaterials after inhalation exposure. Applied in Vitro Toxicology, 7 (3). pp. 112-128. ISSN 2332-1539

Watts, Emily R. and Howden, Andrew J.M. and Morrison, Tyler and Sadiku, Pranvera and Hukelmann, Jens and von Kriegsheim, Alex and Ghesquiere, Bart and Murphy, Fiona and Mirchandani, Ananda S. and Humphries, Duncan C. and Grecian, Robert and Ryan, Eilise M. and Coelho, Patricia and Blanco, Gio Rodriguez and Plant, Tracie M. and Dickinson, Rebecca S. and Finch, Andy and Vermaelen, Wesley and Cantrell, Doreen A. and Whyte, Moira K. and Walmsley, Sarah R. (2021) Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism. Journal of Clinical Investigation, 131 (10). e134073. ISSN 0021-9738

Murphy, Fiona and Dekkers, Susan and Braakhuis, Hedwig and Ma-Hock, Lan and Johnston, Helinor and Janer, Gemma and di Cristo, Luisana and Sabella, Stefania and Jacobsen, Nicklas Raun and Oomen, Agnes G. and Haase, Andrea and Fernandes, Teresa and Stone, Vicki (2021) An integrated approach to testing and assessment of high aspect ratio nanomaterials and its application for grouping based on a common mesothelioma hazard. NanoImpact, 22. 100314. ISSN 2452-0748

Kermanizadeh, Ali and Jacobsen, Nicklas Raun and Murphy, Fiona and Powell, Leagh and Parry, Lee and Zhang, Haiyuan and Møller, Peter (2021) A review of the current state of nanomedicines for targeting and treatment of cancers : achievements and future challenges. Advanced Therapeutics, 4 (2). 2000186. ISSN 2366-3987

2020

Stone, Vicki and Gottardo, Stefania and Bleeker, Eric A.J. and Braakhuis, Hedwig and Dekkers, Susan and Fernandes, Teresa and Haase, Andrea and Hunt, Neil and Hristozov, Danail and Jantunen, Paula and Jeliazkova, Nina and Johnston, Helinor and Lamon, Lara and Murphy, Fiona and Rasmussen, Kirsten and Rauscher, Hubert and Jiménez, Araceli Sánchez and Svendsen, Claus and Spurgeon, David and Vázquez-Campos, Socorro and Wohlleben, Wendel and Oomen, Agnes G. (2020) A framework for grouping and read-across of nanomaterials- supporting innovation and risk assessment. Nano Today, 35. 100941. ISSN 1878-044X

Peijnenburg, Willie J. G. M. and Ruggiero, Emmanuel and Boyles, Matthew and Murphy, Fiona and Stone, Vicki and Elam, Derek A. and Werle, Kai and Wohll, Wendel (2020) A method to assess the relevance of nanomaterial dissolution during reactivity testing. Materials, 13 (10). 2235. ISSN 1996-1944

Plant, Tracie and Eamsamarng, Suttida and Reyes, Leila and Renshaw, Stephen A. and Coelho, Patricia and Morgan, Jessie May and Ellett, Felix E. and Morrison, Tyler and Humphries, Duncan and Watts, Emily R. and Murphy, Fiona and Raffo-Iraolagoitia, Ximena L. and Zhang, Ailiang and Cash, Jenna L. and Loynes, Catherine and Elks, Philip M. and Van Eeden, Freek and Carlin, Leo M. and Furley, Andrew J.W. and Whyte, Moira K.B. and Walmsley, Sarah R. (2020) Semaphorin 3F signaling actively retains neutrophils at sites of inflammation. Journal of Clinical Investigation, 130 (6). pp. 3221-3237. ISSN 0021-9738

2019

Harris, Alison J. and Mirchandani, Ananda S. and Lynch, Ruairi W. and Murphy, Fiona and Delaney, Liam and Small, Donna and Coelho, Patricia and Watts, Emily R. and Sadiku, Pranvera and Griffith, David and Dickinson, Rebecca S. and Clark, Eilidh and Willson, Joseph A. and Morrison, Tyler and Mazzone, Massimilliano and Carmeliet, Peter and Ghesquiere, Bart and O'Kane, Cecilia and McAuley, Danny and Jenkins, Steve J. and Whyte, Moira K.B. and Walmsley, Sarah R. (2019) IL4RA signaling abrogates hypoxic neutrophil survival and limits acute lung injury responses in vivo. American Journal of Respiratory and Critical Care Medicine, 200 (2). pp. 235-246. ISSN 1535-4970

2017

Dickinson, Rebecca S. and Murphy, Fiona and Doherty, Catherine and Williams, Sam and Mirchandani, Ananda and Willson, Joseph and Scotti, John S. and Preston, Gail and Schofield, Christopher J. and Whyte, Moira K.B. and Walmsley, Sarah R. (2017) Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo. Wellcome Open Research, 2 (104). pp. 1-15. A4. ISSN 2398-502X

Chernova, Tatyana and Murphy, Fiona A. and Galavotti, Sara and Sun, Xiao Ming and Powley, Ian R. and Grosso, Stefano and Schinwald, Anja and Zacarias-Cabeza, Joaquin and Dudek, Kate M. and Dinsdale, David and Le Quesne, John and Bennett, Jonathan and Nakas, Apostolos and Greaves, Peter and Poland, Craig A. and Donaldson, Ken and Bushell, Martin and Willis, Anne E. and MacFarlane, Marion (2017) Long-fiber carbon nanotubes replicate asbestos-induced mesothelioma with disruption of the tumor suppressor gene Cdkn2a (Ink4a/Arf). Current Biology, 27 (21). 3302-3314.e6. ISSN 0960-9822

Sadiku, Pranvera and Willson, Joseph A. and Dickinson, Rebecca S. and Murphy, Fiona and Harris, Alison J. and Lewis, Amy and Sammut, David and Mirchandani, Ananda S. and Ryan, Eilise and Watts, Emily R. and Thompson, A.A.Roger and Marriott, Helen M. and Dockrell, David H. and Taylor, Cormac T. and Schneider, Martin and Maxwell, Patrick H. and Chilvers, Edwin R. and Mazzone, Massimilliano and Moral, Veronica and Pugh, Chris W. and Ratcliffe, Peter J. and Schofield, Christopher J. and Ghesquiere, Bart and Carmeliet, Peter and Whyte, Moira K.B. and Walmsley, Sarah R. (2017) Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses. Journal of Clinical Investigation, 127 (9). pp. 3407-3420. ISSN 0021-9738

Thompson, A. A. Roger and Dickinson, Rebecca S. and Murphy, Fiona and Thomson, John P. and Marriott, Helen M. and Tavares, Adriana and Willson, Joseph and Williams, Lynne and Lewis, Amy and Mirchandani, Ananda and Coelho, Patricia Dos Santos and Doherty, Catherine and Ryan, Eilise and Watts, Emily and Morton, Nicholas M. and Forbes, Shareen and Stimson, Roland H. and Hameed, Abdul G. and Arnold, Nadine and Preston, Julie A. and Lawrie, Allan and Finisguerra, Veronica and Mazzone, Massimiliano and Sadiku, Pranvera and Goveia, Jermaine and Taverna, Federico and Carmeliet, Peter and Foster, Simon J. and Chilvers, Edwin R. and Cowburn, Andrew S. and Dockrell, David H. and Johnson, Randall S. and Meehan, Richard R. and Whyte, Moira K. B. and Walmsley, Sarah R. (2017) Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism. Science Immunology, 2 (8). ISSN 2470-9468

2016

Chernova, T and Sun, X M and Powley, I R and Galavotti, S and Grosso, S and Murphy, F A and Miles, G J and Cresswell, L and Antonov, A V and Bennett, J and Nakas, A and Dinsdale, D and Cain, K and Bushell, M and Willis, A E and MacFarlane, M (2016) Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease. Cell Death and Differentiation, 23 (7). pp. 1152-1164. ISSN 1350-9047

Damby, David E. and Murphy, Fiona A. and Horwell, Claire J. and Raftis, Jennifer and Donaldson, Kenneth (2016) The in vitro respiratory toxicity of cristobalite-bearing volcanic ash. Environmental Research, 145. pp. 74-84. ISSN 1096-0953

2013

Horwell, C.J. and Baxter, P.J. and Hillman, S.E. and Calkins, J.A. and Damby, D.E. and Delmelle, P. and Donaldson, K. and Dunster, C. and Fubini, B. and Kelly, F.J. and Le Blond, J.S. and Livi, K.J.T. and Murphy, F. and Nattrass, C. and Sweeney, S. and Tetley, T.D. and Thordarson, T. and Tomatis, M. (2013) Physicochemical and toxicological profiling of ash from the 2010 and 2011 eruptions of Eyjafjallajökull and Grímsvötn volcanoes, Iceland using a rapid respiratory hazard assessment protocol. Environmental Research, 127. pp. 63-73. ISSN 1096-0953

Damby, D. E. and Horwell, C. J. and Baxter, P. J. and Delmelle, P. and Donaldson, K. and Dunster, C. and Fubini, B. and Murphy, F. A. and Nattrass, C. and Sweeney, S. and Tetley, T. D. and Tomatis, M. (2013) The respiratory health hazard of tephra from the 2010 Centennial eruption of Merapi with implications for occupational mining of deposits. Journal of Volcanology and Geothermal Research, 261. pp. 376-387. ISSN 0377-0273

2012

Murphy, Fiona A. and Schinwald, Anja and Poland, Craig A. and Donaldson, Ken (2012) The mechanism of pleural inflammation by long carbon nanotubes : interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells. Particle and Fibre Toxicology, 9. 8.

2011

Osmond-McLeod, Megan J and Poland, Craig A and Murphy, Fiona and Waddington, Lynne and Morris, Howard and Hawkins, Stephen C and Clark, Steve and Aitken, Rob and McCall, Maxine J and Donaldson, Ken (2011) Durability and inflammogenic impact of carbon nanotubes compared with asbestos fibres. Particle and Fibre Toxicology, 8. 15.

2010

Donaldson, Ken and Murphy, Fiona A. and Duffin, Rodger and Poland, Craig A. (2010) Asbestos, carbon nanotubes and the pleural mesothelium : a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma. Particle and Fibre Toxicology, 7. 5. ISSN 1743-8977

2009

Lu, Senlin and Duffin, Rodger and Poland, Craig and Daly, Paul and Murphy, Fiona and Drost, Ellen and MacNee, William and Stone, Vicki and Donaldson, Ken (2009) Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation. Environmental Health Perspectives, 117 (2). pp. 241-247. ISSN 0091-6765