Asbestos and disease genomics : is mesothelioma a genomic paradigm?

Jaurand, Marie-Claude and Murphy, Fiona and Felley-Bosco, Emanuela (2025) Asbestos and disease genomics : is mesothelioma a genomic paradigm? Frontiers in Toxicology, 6. 1536344. ISSN 2673-3080 (https://doi.org/10.3389/ftox.2024.1536344)

[thumbnail of Jaurand-etal-2025-ftox-Asbestos-and-disease-genomics-is-mesothelioma-a-genomic-paradigm]
Preview
Text. Filename: Jaurand-etal-2025-ftox-Asbestos-and-disease-genomics-is-mesothelioma-a-genomic-paradigm.pdf
Final Published Version
License: Creative Commons Attribution 4.0 logo

Download (624kB)| Preview

Abstract

A paradigm is a set of assumptions that creates a viewpoint of the world. However, as summarized by Carlo Rovelli (Carlo Rovelli, 2016), “scientific knowledge is the process of continuously modifying and improving our conception of the world, selectively and constantly questioning the assumptions on which it is based.” In this Editorial, we aim to challenge the current assumptions surrounding the concept of mesothelioma as a genomic disease through a comprehensive review of our understanding of disease pathogenesis and integration of recent findings reported in this Research Topic (Leinardi et al.; Sekido and Sato; Farahmand et al.; Fisher et al.).

ORCID iDs

Jaurand, Marie-Claude, Murphy, Fiona ORCID logoORCID: https://orcid.org/0000-0001-7925-0632 and Felley-Bosco, Emanuela;