Browse by Author or creator

2019

Henderson, Dave J.P. and Houslay, Miles D. and Bangma, Chris H. and Hoffmann, Ralf (2019) Creating a potential diagnostic for prostate cancer risk stratification (InformMDx™) by translating novel scientific discoveries concerning cAMP degrading phosphodiesterase-4D7 (PDE4D7). Clinical Science, 133 (2). pp. 269-286. ISSN 0143-5221

2015

Houslay, Miles (2015) Hypertension linked to PDE3A activation. Nature Genetics, 47 (6). pp. 562-563. ISSN 1061-4036

Bolger, Graeme B. and Dunlop, Allan J. and Meng, Dong and Day, Jon P. and Klussmann, Enno and Baillie, George S. and Adams, David R. and Houslay, Miles D. (2015) Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains. Cellular Signalling, 27 (4). pp. 756-769. ISSN 1873-3913

2014

Henderson, D J P and Byrne, A and Dulla, K and Jenster, G and Hoffmann, R and Baillie, G S and Houslay, M D (2014) The cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells. British Journal of Cancer, 110 (5). pp. 1278-1287. ISSN 1532-1827

2011

Le Moan, Natacha and Houslay, Daniel and Christian, Frank and Houslay, Miles and Akassoglou, Katerina (2011) Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1α. Molecular Cell, 44 (3). pp. 476-490. ISSN 1097-2765

Ishizuka, Koko and Kamiya, Atsushi and Oh, Edwin and Kanki, Hiroaki and Seshadri, Saurav and Robinson, Jon and Murdoch, Hannah and Dunlop, Allan and Kubo, Ken-ichiro and Furukori, Keiko and Huang, Beverly and Zeledon, Mariela and Hayashi-Takagi, Ariko and Okano, Hideyuki and Nakajima, Kazunori and Houslay, Miles and Katsanis, Nicholas and Sawa, Akira (2011) DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature, 473 (7345). pp. 92-96. ISSN 0028-0836

2009

Vecsey, Christopher and Baillie, George and Jaganath, Devan and Havekes, Robbert and Daniels, Andrew and Wimmer, Mathieu and Huang, Ted and Brown, Kim and Li, Xiang-Yao and Descalzi, Giannina and Kim, Susan and Chen, Tao and Shang, Yu-Ze and Zhuo, Min and Houslay, Miles and Abel, Ted (2009) Sleep deprivation impairs cAMP signalling in the hippocampus. Nature, 461. pp. 1122-1125. ISSN 0028-0836

Li, Xiang and Baillie, George and Houslay, Miles (2009) Mdm2 directs the ubiquitination of β-arrestin-sequestered cAMP phosphodiesterase-4D5. Journal of Biological Chemistry, 284 (24). pp. 16170-16182. ISSN 1083-351X

2008

Huston, Elaine and Lynch, Martin and Mohamed, Ahmed and Collins, Daniel and Hill, Elaine and MacLeod, Ruth and Krause, Eberhard and Baillie, George and Houslay, Miles (2008) EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation. Proceedings of the National Academy of Sciences, 105 (35). pp. 12791-12796. ISSN 0027-8424

2007

Millar, J. Kirsty and Mackie, Shaun and Clapcote, Steven J. and Murdoch, Hannah and Pickard, Ben S. and Christie, Sheila and Muir, Walter J. and Blackwood, Douglas H. and Roder, John C. and Houslay, Miles D. and Porteous, David J. (2007) Disrupted in schizophrenia 1 and phosphodiesterase 4B : towards an understanding of psychiatric illness. Journal of Physiology, 584 (2). pp. 401-405. ISSN 0022-3751

2005

Millar, J. Kirsty and Pickard, Benjamin S. and Mackie, Shaun and James, Rachel and Christie, Sheila and Buchanan, Sebastienne R. and Malloy, M. Pat and Chubb, Jennifer E. and Huston, Elaine and Baillie, George S. and Thomson, Pippa A. and Hill, Elaine V. and Brandon, Nicholas J. and Rain, Jean-Christophe and Camargo, L. Miguel and Whiting, Paul J. and Houslay, Miles D. and Blackwood, Douglas H. R. and Muir, Walter J. and Porteous, David J. (2005) DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science, 310 (5751). pp. 1187-1191. ISSN 1095-9203