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2022

Al-Qazazi, Ruaa and Lima, Patricia D.A. and Prisco, Sasha Z. and Potus, Francois and Dasgupta, Asish and Chen, Kuang-Hueih and Tian, Lian and Bentley, Rachel E. T. and Mewburn, Jeff and Martin, Ashley Y. and Wu, Danchen and Jones, Oliver and Maurice, Donald H. and Bonnet, Sebastien and Provencher, Steeve and Prins, Kurt W. and Archer, Stephen L. (2022) Macrophage-NLRP3 activation promotes right ventricle failure in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine, 206 (5). pp. 608-624. ISSN 1535-4970

Xiong, Ping Yu and Motamed, Mehras and Chen, Kuang-Hueih and Dasgupta, Asish and Potus, François and Tian, Lian and Martin, Ashley and Mewburn, Jeffrey and Jones, Oliver and Thébaud, Arthur and Archer, Stephen L. (2022) Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding. Acta Physiologica, 234 (2). e13764. ISSN 1748-1708

2021

Dasgupta, Asish and Chen, Kuang-Hueih and Lima, Patricia D.A. and Mewburn, Jeffrey and Wu, Danchen and Al-Qazazi, Ruaa and Jones, Oliver and Tian, Lian and Potus, Francois and Bonnet, Sebastien and Archer, Stephen L. (2021) PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension. FASEB Journal, 35 (8). e21771. ISSN 0892-6638

Wu, Danchen and Dasgupta, Asish and Read, Austin D. and Bentley, Rachel E.T. and Motamed, Mehras and Chen, Kuang-Hueih and Al-Qazazi, Ruaa and Mewburn, Jeffrey D. and Dunham-Snary, Kimberly J. and Alizadeh, Elahe and Tian, Lian and Archer, Stephen L. (2021) Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer. Free Radical Biology and Medicine, 170. pp. 150-178. ISSN 0891-5849

2020

Prisco, Sasha Z. and Rose, Lauren and Potus, Francois and Tian, Lian and Wu, Danchen and Hartweck, Lynn and Al-Qazazi, Ruaa and Neuber-Hess, Monica and Eklund, Megan and Hsu, Steven and Thenappan, Thenappan and Archer, Stephen L. and Prins, Kurt W. (2020) Excess protein O-GlcNAcylation links metabolic derangements to right ventricular dysfunction in pulmonary arterial hypertension. International Journal of Molecular Sciences, 21 (19). 7278. ISSN 1422-0067

Tian, Lian and Xiong, Ping Yu and Alizadeh, Elahe and Lima, Patricia D. A. and Potus, François and Mewburn, Jeffrey and Martin, Ashley and Chen, Kuang-Hueih and Archer, Stephen L. (2020) Supra-coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion. Acta Physiologica, 229 (4). e13483. ISSN 1748-1708

Potus, François and Pauciulo, Michael W. and Cook, Elina K. and Zhu, Na and Hsieh, Alexander and Welch, Carrie L. and Shen, Yufeng and Tian, Lian and Lima, Patricia and Mewburn, Jeffrey and D’Arsigny, Christine L. and Lutz, Katie A. and Coleman, Anna W. and Damico, Rachel and Snetsinger, Brooke and Martin, Ashley Y. and Hassoun, Paul M. and Nichols, William C. and Chung, Wendy K. and Rauh, Michael J. and Archer, Stephen L. (2020) Novel mutations and decreased expression of the epigenetic regulator TET2 in pulmonary arterial hypertension. Circulation, 141 (24). pp. 1986-2000. ISSN 0009-7322

Tian, Lian and Wu, Danchen and Dasgupta, Asish and Chen, Kuang-Hueih and Mewburn, Jeffrey and Potus, Francois and Lima, Patricia D.A. and Hong, Zhigang and Zhao, Yuan-Yuan and Hindmarch, Charles C.T. and Kutty, Shelby and Provencher, Steeve and Bonnet, Sebastien and Sutendra, Gopinath and Archer, Stephen L. (2020) Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension : a pyruvate dehydrogenase kinase-dependent shift in mitochondrial metabolism promotes right ventricular fibrosis. Circulation Research, 126 (12). pp. 1723-1745. ISSN 0009-7330

Dasgupta, Asish and Wu, Danchen and Tian, Lian and Xiong, Ping Yu and Dunham-Snary, Kimberly J. and Chen, Kuang-Hueih and Alizadeh, Elahe and Motamed, Mehras and Potus, François and Hindmarch, Charles C.T. and Archer, Stephen L. (2020) Mitochondria in the pulmonary vasculature in health and disease : oxygen-sensing, metabolism, and dynamics. Comprehensive Physiology, 10 (2). pp. 713-765.

2019

Xiong, Ping Yu and Tian, Lian and Dunham-Snary, Kimberly J. and Chen, Kuang-Hueih and Mewburn, Jeffrey D. and Neuber-Hess, Monica and Martin, Ashley and Dasgupta, Asish and Potus, Francois and Archer, Stephen L. (2019) Biventricular increases in mitochondrial fission mediator (MiD51) and proglycolytic pyruvate kinase (PKM2) isoform in experimental of group 2 pulmonary hypertension-novel mitochondrial abnormalities. Frontiers in Cardiovascular Medicine, 5. 195.

2018

Tian, Lian and Potus, Francois and Wu, Danchen and Dasgupta, Asish and Chen, Kuang-Hueih and Mewburn, Jeffrey and Lima, Patricia and Archer, Stephen L. (2018) Increased Drp1-mediated mitochondrial fission promotes proliferation and collagen production by right ventricular fibroblasts in experimental pulmonary arterial hypertension. Frontiers in Physiology, 9. 828. ISSN 1664-042X

2017

Prins, Kurt W. and Tian, Lian and Wu, Danchen and Thenappan, Thenappan and Metzge, Joseph M. and Archer, Stephen L. (2017) Colchicine depolymerizes microtubules, increases junctophilin-2, and improves right ventricular function in experimental pulmonary arterial hypertension. Journal of the American Heart Association, 6 (6). e006195. ISSN 2047-9980

Tian, Lian and Neuber-Hess, Monica and Mewburn, Jeffrey and Dasgupta, Asish and Dunham-Snary, Kimberly and Wu, Danchen and Chen, Kuang-Hueih and Hong, Zhigang and Sharp, Willard W. and Kutty, Shelby and Archer, Stephen L. (2017) Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension. Journal of Molecular Medicine, 95 (4). pp. 381-393. ISSN 0946-2716

Hong, Zhigang and Chen, Kuang-Hueih and DasGupta, Asish and Potus, Francois and Dunham-Snary, Kimberly and Bonnet, Sebastien and Tian, Lian and Fu, Jennifer and Breuils-Bonnet, Sandra and Provencher, Steeve and Wu, Danchen and Mewburn, Jeffrey and Ormiston, Mark L. and Archer, Stephen L. (2017) MicroRNA-138 and microRNA-25 down-regulate mitochondrial calcium uniporter, causing the pulmonary arterial hypertension cancer phenotype. American Journal of Respiratory and Critical Care Medicine, 195 (4). pp. 515-529. ISSN 1535-4970

2016

Tian, Lian and Wang, Zhijie and Liu, Yuming and Eickhoff, Jens C. and Eliceiri, Kevin W. and Chesler, Naomi C. (2016) Validation of an arterial constitutive model accounting for collagen content and crosslinking. Acta Biomaterialia, 31. pp. 276-287. ISSN 1742-7061

2015

Ryan, John J. and Huston, Jessica and Kutty, Shelby and Hatton, Nathan D. and Bowman, Lindsay and Tian, Lian and Herr, Julia E. and Johri, Amer M. and Archer, Stephen L. (2015) Right ventricular adaptation and failure in pulmonary arterial hypertension. Canadian Journal of Cardiology, 31 (4). pp. 391-406.

Golob, Mark J and Tian, Lian and Wang, Zhijie and Zimmerman, Todd A. and Caneba, Christine A. and Hacker, Timothy A. and Song, Guoqing and Chesler, Naomi (2015) Mitochondria DNA mutations cause sex-dependent development of hypertension and alterations in cardiovascular function. Journal of Biomechanics, 48 (3). pp. 405-412. ISSN 0021-9290