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McGee, Leah M.C. and Carpinteyro Sanchez, Alemao G. and Perieteanu, Marina and Eskandari, Kaveh and Bian, Yan and Mackie, Logan and Young, Louise and Beveridge, Rebecca and Suckling, Colin J. and Roberts, Craig W. and Scott, Fraser J. (2024) Strathclyde Minor Groove Binders (S-MGBs) with activity against Acanthamoeba castellanii. Journal of Antimicrobial Chemotherapy, 79 (9). pp. 2251-2258. dkae221. ISSN 0305-7453
Riley, Christopher and Ammar, Usama and Alsfouk, Aisha and Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Breen, David and Huggan, Judith and Lawson, Christopher and McIntosh, Kathryn and Plevin, Robin and Suckling, Colin J. and Young, Louise C. and Paul, Andrew and Mackay, Simon P. (2024) Design and synthesis of novel aminoindazole-pyrrolo[2,3-b]pyridine inhibitors of IKKα that selectively perturb cellular non-canonical NF-κB signalling. Molecules, 29 (15). 3515. ISSN 1420-3049
Singh, Sanju and Nwagwu, Elizabeth and Young, Louise and Kumar, Pankaj and Shinde, Pramod B. and Edrada-Ebel, RuAngelie (2024) Targeted isolation of antibiofilm compounds from halophytic endophyte Bacillus velezensis 7NPB-3B using LC-HR-MS-based metabolomics. Microorganisms, 12 (2). 413. ISSN 2076-2607
Atoum, Dana and Fernandez-Pastor, Ignacio and Young, Louise and Edrada-Ebel, RuAngelie (2023) Use of multivariate analysis to unravel the differences between two chamomile varieties and their anticancer and antioxidant activities. Plants, 12 (12). 2297. ISSN 2223-7747
Hughes, Alison H. and Magot, Florent and Tawfike, Ahmed F. and Rad-Menéndez, Cecilia and Thomas, Naomi and Young, Louise C. and Stucchi, Laura and Carettoni, Daniele and Stanley, Michele S. and Edrada-Ebel, RuAngelie and Duncan, Katherine R. (2021) Exploring the chemical space of macro- and micro-algae using comparative metabolomics. Microorganisms, 9 (2). 311. ISSN 2076-2607
Haselager, Marco and Thijssen, Rachel and West, Christopher and Young, Louise and Van Kampen, Roel and Willmore, Elaine and Mackay, Simon and Kater, Arnon and Eldering, Eric (2021) Regulation of Bcl-XL by non-canonical NF-κB in the context of CD40-induced drug resistance in CLL. Cell Death and Differentiation, 28 (5). pp. 1658-1668. ISSN 1350-9047
Obeid, Mohammad A and Gany, Siti Aisya and Gray, Alexander I and Young, Louise and Igoli, John O and Ferro, Valerie (2020) Niosome-encapsulated balanocarpol : compound isolation, characterisation, and cytotoxicity evaluation against human breast and ovarian cancer cell lines. Nanotechnology, 31 (19). 195101. ISSN 0957-4484
Tawfike, Ahmed F. and Romli, Muhammad and Clements, Carol and Abbott, Gráinne and Young, Louise and Schumacher, Marc and Diederich, Marc and Farag, Mohamed and Edrada-Ebel, RuAngelie (2019) Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based metabolomics. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1106-1107. pp. 71-83. ISSN 1570-0232
Semaan, D.G. and Igoli, J.O. and Young, L. and Gray, A.I. and Rowan, E.G. and Marrero, E. (2018) In vitro anti-diabetic effect of flavonoids and pheophytins from Allophylus cominia Sw. on the glucose uptake assays by HepG2, L6, 3T3-L1 and fat accumulation in 3T3-L1 adipocytes. Journal of Ethnopharmacology, 216. pp. 8-17. ISSN 1872-7573
Semaan, D. G. and Igoli, J. O. and Young, L. and Marrero, E. and Gray, A. I. and Rowan, E. G. (2018) Dataset on the kinetics of the inhibition of PTP1B by the flavonoids and pheophytin A from Allophylus cominia. Data in Brief, 17. pp. 401-406.
Tawfike, Ahmed F. and Abbott, Grainne and Young, Louise and Edrada-Ebel, Ruangelie (2018) Metabolomic-guided isolation of bioactive natural products from Curvularia sp., an endophytic fungus of Terminalia laxiflora. Planta Medica, 84 (3). pp. 182-190. ISSN 0032-0943
Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Boyd, Marie and Breen, David and Edwards, Joanne and Gamble, Carly and Gray, Alexander I. and Harvey, Alan L. and Hatziieremia, Sophia and Ho, Ka Ho and Huggan, Judith K. and Lang, Stuart and Llona-Minguez, Sabin and Luo, Jia Lin and McIntosh, Kathryn and Paul, Andrew and Plevin, Robin J. and Robertson, Murray N. and Scott, Rebecca and Suckling, Colin J. and Sutcliffe, Oliver Brook and Young, Louise C. and MacKay, Simon P. (2017) Inhibitory Kappa B kinase α (IKKα) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers. Journal of Medicinal Chemistry, 60 (16). pp. 7043-7066. ISSN 0022-2623
Obeid, Mohammad A. and Elburi, Ashref and Young, Louise C. and Mullen, Alexander B. and Tate, Rothwelle J. and Ferro, Valerie A. (2017) Formulation of Nonionic Surfactant Vesicles (NISV) prepared by microfluidics for therapeutic delivery of siRNA into cancer cells. Molecular Pharmaceutics, 14 (7). pp. 2450-2458. ISSN 1543-8384
Tawfike, A F and Tate, R and Abbott, G and Young, L and Viegelmann, C and Schumacher, Marc and Diederich, Marc and Edrada-Ebel, R.A. (2017) Metabolomic tools to assess the chemistry and bioactivity of endophytic aspergillus strain. Chemistry and Biodiversity. ISSN 1612-1872
Semaan, D.G. and Igoli, J.O. and Young, L. and Marrero, E. and Gray, A.I. and Rowan, E.G. (2017) In vitro anti-diabetic activity of flavonoids and pheophytins from Allophylus cominia Sw . on PTP1B, DPPIV, alpha-glucosidase and alpha-amylase enzymes. Journal of Ethnopharmacology, 203. pp. 39-46. ISSN 1872-7573
Alonezi, Sanad and Tusiimire, Jonans and Wallace, Jennifer and Dufton, Mark J. and Parkinson, John A. and Young, Louise C. and Clements, Carol J. and Park, Jin-Kyu and Jeon, Jong-Woon and Ferro, Valerie A. and Watson, David G. (2017) Metabolomic profiling of the synergistic effects of melittin in combination with cisplatin on ovarian cancer cells. Metabolites, 7 (14). pp. 1-18. ISSN 2218-1989
Miller, Lisa M. and Keune, Willem-Jan and Castagna, Diana and Young, Louise C. and Duffy, Emma L. and Potjewyd, Frances and Salgado-Polo, Fernando and Garcia, Paloma Engel and Semaan, Dima and Pritchard, John M. and Perrakis, Anastassis and Macdonald, Simon J. F. and Jamieson, Craig and Watson, Allan J. B. (2017) Structure-activity relationships of small molecule autotaxin inhibitors with a discrete binding mode. Journal of Medicinal Chemistry, 60 (2). pp. 722-748. ISSN 0022-2623
Niwasabutra, K and Igoli, J O and Young, L and Gray, A I and Ferro, V A (2016) Effects of crude extracts from mushrooms on different cancer cell lines. Planta Medica, 81 (S 01). S1-S381. ISSN 0032-0943
Alzahrani, A and Abbott, G and Young, L C and Igoli, J and Gray, A I and Ferro, V A (2016) Phytochemical and biological investigation of Calliandra surinamensis as a potential treatment for diabetes. Planta Medica, 81 (S 01). S1-S381. ISSN 0032-0943
Alonezi, Sanad and Tusiimire, Jonans and Wallace, Jennifer and Dufton, Mark J. and Parkinson, John A. and Young, Louise C. and Clements, Carol J. and Park, Jin Kyu and Jeon, Jong Woon and Ferro, Valerie A. and Watson, David G. (2016) Metabolomic profiling of the effects of melittin on cisplatin resistant and cisplatin sensitive ovarian cancer cells using mass spectrometry and biolog microarray technology. Metabolites, 6 (4). ISSN 2218-1989
Tusiimire, Jonans and Wallace, Jennifer and Woods, Nicola and Dufton, Mark J. and Parkinson, John A. and Abbott, Grainne and Clements, Carol J. and Young, Louise and Park, Jin Kyu and Jeon, Jong Woon and Ferro, Valerie A. and Watson, David G. (2016) Effect of bee venom and its fractions on the release of pro-inflammatory cytokines in PMA-differentiated U937 cells co-stimulated with LPS. Vaccines, 4 (2). 11. ISSN 2076-393X
Wan-Mohtar, Wan Abd Al Qadr Imad and Young, Louise and Abbott, Gráinne M. and Clements, Carol and Harvey, Linda M. and McNeil, Brian (2016) Antimicrobial properties and cytotoxicity of sulfated (1,3)-β-D-glucan from the mycelium of the mushroom Ganoderma lucidum. Journal of Microbiology and Biotechnology, 26 (6). pp. 999-1010. ISSN 1738-8872
Purves, Kevin and Macintyre, Lynsey and Brennan, Debra and Hreggviðsson, Guðmundur Ó. and Kuttner, Eva and Ásgeirsdóttir, Margrét E. and Young, Louise C. and Green, David H. and Edrada-Ebel, Ruangelie and Duncan, Katherine (2016) Using molecular networking for microbial secondary metabolite bioprospecting. Metabolites, 6 (1). 2. ISSN 2218-1989
Castagna, Diana and Duffy, Emma L. and Semaan, Dima and Young, Louise C. and Pritchard, John M. and Macdonald, Simon J. F. and Budd, David C. and Jamieson, Craig and Watson, Allan J. B. (2015) Identification of a novel class of autotaxin inhibitors through cross-screening. MedChemComm, 2015 (6). pp. 1149-1155. ISSN 2040-2503
Sánchez Calero, Janet and Young, Louise C. and Marrero Faz, Evangelina and L. Harvey, Alan (2014) Efecto inhibitorio de un extracto acuoso de las hojas de Allophylus cominia (L.) Sw sobre las proteínas tirosina fosfatasa 1B y dipeptidil peptidasa IV. Revista Cubana de Farmacia, 48 (4). pp. 672-683. ISSN 1561-2988
Tawfike, Ahmed Fares and Edrada-Ebel, Ruangelie and Tate, Roth and Diederich, Marc and Schumacher, Marc and Sawadogo, Richard and Clements, Carol and Young, Louise (2014) Metabolomics and dereplication studies of endophytic metabolites from some Egyptian medicinal plants in the search potential antimicrobial drugs. In: Metabolomics 2014, 2014-06-23 - 2014-06-26, Daiichi Hotel Tsuruoka and Marica/Washington Hotel.
Viegelmann, Christina and Parker, Jennifer and Ooi, Thengtheng and Clements, Carol and Abbott, Gráinne and Young, Louise and Kennedy, Jonathan and Dobson, Alan D W and Edrada-Ebel, RuAngelie (2014) Isolation and identification of antitrypanosomal and antimycobacterial active steroids from the sponge haliclona simulans. Marine Drugs, 12 (5). pp. 2937-2952. ISSN 1660-3397
Marrero-Faz, Evangelina and Sánchez-Calero, Janet and Young, Louise and Harvey, Alan (2014) Efecto inhibidor del extracto acuoso de hojas de Persea americana Mill y sus fracciones sobre PTP1B como diana terapéutica para la diabetes tipo 2. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, 13 (2). pp. 144-151.
Harvey, Alan L and Young, Louise C and Kornisiuk, Edgar and Snitcofsky, Marina and Colettis, Natalia and Blanco, Carlos and Jerusalinsky, Diana and Jamieson, Andrew G and Hartley, Richard C and Stone, Trevor W (2012) A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A(1) receptors and enhances consolidation of step-down avoidance. Behavioural Brain Research, 234 (2). pp. 184-191. ISSN 1872-7549
Mains, Jenifer and Tan, Lay Ean and Zhang, Wei and Young, Louise and Shi, Ruiwen and Wilson, Clive (2012) Species variation in small molecule components of animal vitreous. Investigative Ophthalmology and Visual Science, 53 (8). pp. 4778-4786. ISSN 0146-0404
Harvey, Alan L and Young, Louise C and Viljoen, Alvaro M and Gericke, Nigel P (2011) Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids. Journal of Ethnopharmacology, 137 (3). 1124–1129. ISSN 1872-7573
Bansal, Ranju and Guleria, Sheetal and Young, Louise C and Harvey, Alan L (2011) Synthesis of quaternary ammonium salts of 16E-[4-(2-alkylaminoethoxy)-3-methoxybenzylidene]androstene derivatives as skeletal muscle relaxants. Steroids, 76 (3). pp. 254-260.
Bansal, Ranju and Kumar, Gulshan and Gandhi, Deepika and Young, Louise C and Harvey, Alan L (2011) Synthesis of a new series of 1H-imidazol-1-yl substituted 8-phenylxanthines as adenosine receptor ligands. Chemistry and Biodiversity, 8 (7). pp. 1290-1300.
Shittu, H and Gray, Alexander and Furman, Brian and Young, Louise (2010) Glucose uptake stimulatory effect of akuammicine from picralima nitida (Apocynaceae). Phytochemistry Letters, 3 (1). pp. 53-55.
Bansal, Ranju and Kumar, Gulshan and Gandhi, Deepika and Yadav, Rakesh and Young, Louise C and Harvey, Alan L (2010) Synthesis of 8-(cyclopentyloxy)phenyl substituted xanthine derivatives as adenosine A2A ligands. Arzneimittel Forschung, 60 (3). pp. 131-136. ISSN 0004-4172
Bansal, R. and Kumar, G. and Gandhi, D. and Young, Louise C. and Harvey, A.L. (2009) Synthesis of a series of 8-(substituted-phenyl)xanthines and a study on the effects of substitution pattern of phenyl substituents on affinity for adenosine A(1) and A(2A) receptors. European Journal of Medicinal Chemistry, 44 (5). pp. 2122-2127. ISSN 0223-5234
MacGregor, Duncan G and Mallon, Andrew P and Harvey, Alan L and Young, Louise and Nimmo, Hugh G and Stone, Trevor W (2007) Group S8A serine proteases, including a novel enzyme cadeprin, induce long-lasting, metabotropic glutamate receptor-dependent synaptic depression in rat hippocampal slices. European Journal of Neuroscience, 26 (7). pp. 1870-80. ISSN 0953-816X
Suckling, C.J. and Murphy, J.A. and Khalaf, A.I. and Zhou, S. and Lizos, D.E. and Nguyen Van Nhien, A. and Yasumatsu, H. and McVie, A. and Young, L.C. and McCraw, C. and Waterman, P.G. and Morris, B.J. and Pratt, J.A. and Harvey, A. (2007) M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds. Bioorganic and Medicinal Chemistry Letters, 17 (9). pp. 2649-2655. ISSN 0960-894X
McKenna, M T and Proctor, G R and Young, L C and Harvey, A L (1997) Novel tacrine analogues for potential use against Alzheimer's disease : potent and selective acetylcholinesterase inhibitors and 5-HT uptake inhibitors. Journal of Medicinal Chemistry, 40 (22). pp. 3516-3523. ISSN 0022-2623
Gendeh, G S and Young, L C and de Medeiros, C L and Jeyaseelan, K and Harvey, A L and Chung, M C (1997) A new potassium channel toxin from the sea anemone Heteractis magnifica : isolation, cDNA cloning, and functional expression. BMC Biochemistry, 36 (38). pp. 11461-11471. ISSN 1471-2091