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Number of items: 74.

Article

Wilson, Clive G. and Aarons, Leon and Augustijns, Patrick and Brouwers, Joachim and Darwich, Adam S. and De Waal, Tom and Garbacz, Grzegorz and Hansmann, Simone and Hoc, Dagmara and Ivanova, Anela and Koziolek, Mirko and Reppas, Christos and Schick, Philipp and Vertzoni, Maria and García-Horsman, J. Arturo (2022) Integration of advanced methods and models to study drug absorption and related processes : an UNGAP perspective. European Journal of Pharmaceutical Sciences, 172. 106100. ISSN 0928-0987

Senekowitsch, Stefan and Schick, Philipp and Abrahamsson, Bertil and Augustijns, Patrick and Gießmann, Thomas and Lennernäs, Hans and Matthys, Christophe and Marciani, Luca and Pepin, Xavier and Perkins, Alan and Feldmüller, Maximilian and Sulaiman, Sarah and Weitschies, Werner and Wilson, Clive G. and Corsetti, Maura and Koziolek, Mirko (2022) Application of in vivo imaging techniques and diagnostic tools in oral drug delivery research. Pharmaceutics, 14 (4). 801. ISSN 1999-4923

Adrianto, Muhammad Faris and Annuryanti, Febri and Wilson, Clive G. and Sheshala, Ravi and Thakur, Raghu Raj Singh (2021) In vitro dissolution testing models of ocular implants for posterior segment drug delivery. Drug Delivery and Translational Research. ISSN 2190-393X

Vinarov, Zahari and Abdallah, Mohammad and Agundez, José A.G. and Allegaert, Karel and Basit, Abdul W. and Braeckmans, Marlies and Ceulemans, Jens and Corsetti, Maura and Griffin, Brendan T. and Grimm, Michael and Keszthelyi, Daniel and Koziolek, Mirko and Madla, Christine M. and Matthys, Christophe and McCoubrey, Laura E. and Mitra, Amitava and Reppas, Christos and Stappaerts, Jef and Steenackers, Nele and Trevaskis, Natalie L. and Vanuytsel, Tim and Vertzoni, Maria and Weitschies, Werner and Wilson, Clive and Augustijns, Patrick (2021) Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics : an UNGAP review. European Journal of Pharmaceutical Sciences, 162. 105812. ISSN 0928-0987

Vinarov, Zahari and Abrahamsson, Bertil and Artursson, Per and Batchelor, Hannah and Berben, Philippe and Bernkop-Schnürch, Andreas and Butler, James and Ceulemans, Jens and Davies, Nigel and Dupont, Didier and Flaten, Gøril Eide and Fotaki, Nikoletta and Griffin, Brendan T. and Jannin, Vincent and Keemink, Janneke and Kesisoglou, Filippos and Koziolek, Mirko and Kuentz, Martin and Mackie, Alan and Meléndez-Martínez, Antonio J. and McAllister, Mark and Müllertz, Anette and O'Driscoll, Caitriona M. and Parrott, Neil and Paszkowska, Jadwiga and Pavek, Petr and Porter, Christopher J.H. and Reppas, Christos and Stillhart, Cordula and Sugano, Kiyohiko and Toader, Elena and Valentová, Kateřina and Vertzoni, Maria and De Wildt, Saskia N. and Wilson, Clive G. and Augustijns, Patrick (2021) Current challenges and future perspectives in oral absorption research : an opinion of the UNGAP network. Advanced Drug Delivery Reviews, 171. pp. 289-331. ISSN 0169-409X

Pyper, Kate and Brouwers, Joachim and Augustijns, Patrick and Khadra, I. and Dunn, C. and Wilson, C.G. and Halbert, G.W. (2020) Multidimensional analysis of human intestinal fluid composition. European Journal of Pharmaceutics and Biopharmaceutics, 153. pp. 226-240. ISSN 0939-6411

McPherson, Stephanie and Perrier, Jeremy and Dunn, Claire and Khadra, Ibrahim and Davidson, Scott and Ainousah, Bayan and Wilson, Clive G. and Halbert, Gavin (2020) Small scale design of experiment investigation of equilibrium solubility in simulated fasted and fed intestinal fluid. European Journal of Pharmaceutics and Biopharmaceutics, 150. pp. 14-23. ISSN 0939-6411

Etherson, Kelly and Dunn, Claire and Matthews, Wayne and Pamelund, Henrik and Barragat, Camille and Sanderson, Natalie and Izumi, Toshiko and da Costa Mathews, Claudia and Halbert, Gavin and Wilson, Clive and McAllister, Mark and Mann, James and Østergaard, Jesper and Butler, James and Khadra, Ibrahim (2020) An interlaboratory investigation of intrinsic dissolution rate determination using surface dissolution. European Journal of Pharmaceutics and Biopharmaceutics, 150. pp. 24-32. ISSN 0939-6411

Vertzoni, Maria and Augustijns, Patrick and Grimm, Michael and Koziolek, Mirko and Lemmens, Glenn and Parrott, Neil and Pentafragka, Christina and Reppas, Christos and Rubbens, Jari and Van Den Αbeele, Jens and Vanuytsel, Tim and Weitschies, Werner and Wilson, Clive G. (2019) Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption : an UNGAP review. European Journal of Pharmaceutical Sciences, 134. pp. 153-175. ISSN 0928-0987

Dunn, Claire and Perrier, Jeremy and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W. (2019) The topography of simulated intestinal equilibrium solubility. Molecular Pharmaceutics, 16 (5). pp. 1890-1905. ISSN 1543-8384

Hall Barrientos, Ivan Joseph and MacKenzie, Graeme R. and Wilson, Clive G. and Lamprou, Dimitrios A. and Coats, Paul (2019) Biological performance of electrospun polymer fibres. Materials, 12 (3). 363. ISSN 1996-1944

Tran, Simon H. and Wilson, Clive G. and Seib, F. Philipp (2018) A review of the emerging role of silk for the treatment of the eye. Pharmaceutical Research, 35 (12). 248. ISSN 0724-8741

Perrier, Jeremy and Zhou, Zhou and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin (2018) Statistical investigation of the full concentration range of fasted and fed simulated intestinal fluid on the equilibrium solubility of oral drugs. European Journal of Pharmaceutical Sciences, 111. pp. 247-256. ISSN 0928-0987

Ainousah, Bayan E and Perrier, Jeremy and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W (2017) Dual level statistical investigation of equilibrium solubility in simulated fasted and fed intestinal fluid. Molecular Pharmaceutics, 14 (12). pp. 4170-4180. ISSN 1543-8384

Hall Barrientos, Ivan J. and Paladino, Eleonora and Szabó, Peter and Brozio, Sarah and Hall, Peter J. and Oseghale, Charles I. and Passarelli, Melissa K. and Moug, Susan J. and Black, Richard A. and Wilson, Clive G. and Zelkó, Romana and Lamprou, Dimitrios A. (2017) Electrospun collagen-based nanofibres : a sustainable material for improved antibiotic utilisation in tissue engineering applications. International Journal of Pharmaceutics, 531 (1). pp. 67-79. ISSN 1873-3476

Zhou, Zhou and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W. (2017) Influence of physiological gastrointestinal surfactant ratio on the equilibrium solubility of BCS class II drugs investigated using a four component mixture design. Molecular Pharmaceutics. ISSN 1543-8384

Zhou, Zhou and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W. (2017) Statistical investigation of simulated fed intestinal media composition on the equilibrium solubility of oral drugs. European Journal of Pharmaceutical Sciences, 99. pp. 95-104. ISSN 0928-0987

Hall Barrientos, Ivan and Paladino, Eleonora and Brozio, Sarah and Passarelli, Melissa K. and Moug, Susan and Black, Richard A. and Wilson, Clive G. and Lamprou, Dimitrios A. (2017) Fabrication and characterisation of drug-loaded electrospun polymeric nanofibers for controlled release in hernia repair. International Journal of Pharmaceutics, 517 (1-2). 329–337. ISSN 1873-3476

Wilson, Clive G. and Halbert, Gavin W. and Mains, Jenifer (2016) The gut in the beaker : missing the surfactants. International Journal of Pharmaceutics, 514 (1). pp. 73-80. ISSN 1873-3476

Gomaa, Yasmine A. and Garland, Martin J. and McInnes, Fiona J. and Donnelly, Ryan F. and El-Khordagui, Labiba K. and Wilson, Clive G. (2014) Microneedle/nanoencapsulation-mediated transdermal delivery : mechanistic insights. European Journal of Pharmaceutics and Biopharmaceutics, 86 (2). pp. 145-155. ISSN 0939-6411

Mains, Jenifer and Wilson, Clive (2012) The vitreous humor as a barrier to nanoparticle distribution. Journal of Ocular Pharmacology and Therapeutics. ISSN 1080-7683

Wilson, Clive (2012) From bench to bedside : designing oral drug formulations. Eesti Arst, 91 (9). 470–477.

Hodges, Lee Ann and Connolly, S.M. and Winter, John and Schmidt, Thomas. J. and Stevens, Howard and Hayward, Marshall and Wilson, Clive (2012) Modulation of gastric pH by a buffered soluble effervescent formulation : a possible means of improving gastric tolerability of alendronate. International Journal of Pharmaceutics, 432. pp. 57-62. ISSN 1873-3476

Mains, Jenifer and Tan, Lay Ean and Zhang, Wei and Young, Louise and Shi, Ruiwen and Wilson, Clive (2012) Species variation in small molecule components of animal vitreous. Investigative Ophthalmology and Visual Science, 53 (8). pp. 4778-4786. ISSN 0146-0404

Mains, Jenifer and Tan, Lay Ean and Wilson, Clive and Urquhart, Andrew (2012) A pharmacokinetic study of a combination of beta adrenoreceptor antagonists : In the isolated perfused ovine eye. European Journal of Pharmaceutics and Biopharmaceutics, 80 (2). pp. 393-401. ISSN 0939-6411

Gomaa, Yasmine and Garland, M.J. and McInnes, Fiona and Donnelly, Ryan and El Khordagui, Labiba and Wilson, Clive (2012) Flux of ionic dyes across microneedle-treated skin : effect of molecular characteristic. International Journal of Pharmaceutics. ISSN 1873-3476

Mains, Jenifer and Wilson, Clive and Urquhart, Andrew (2011) ToF-SIMS analysis of ocular tissues reveals biochemical differentiation and drug distribution. European Journal of Pharmaceutics and Biopharmaceutics, 79 (2). 328–333. ISSN 0939-6411

Mains, Jenifer and Wilson, Clive G. and Urquhart, Andrew (2011) ToF-SIMS analysis of dexamethasone distribution in the isolated perfused eye. Investigative Ophthalmology and Visual Science, 52 (11). pp. 8413-8419. ISSN 0146-0404

Wilson, C. G. and Clarke, Cyril P. and Starkey, Yan Yan L. and Clarke, Geoffrey D. (2011) Comparison of a novel fast-dissolving acetaminophen tablet formulation (FD-APAP) and standard acetaminophen tablets using gamma scintigraphy and pharmacokinetic studies. Drug Development and Industrial Pharmacy, 37 (7). pp. 747-753. ISSN 0363-9045

Shah, Hardik K and Conkie, Jim A and Tait, Robert C and Johnson, James R and Wilson, Clive G (2011) A novel, biodegradable and reversible polyelectrolyte platform for topical-colonic delivery of pentosan polysulphate. International Journal of Pharmaceutics, 404 (1-2). pp. 124-132. ISSN 1873-3476

Tan, Lay Ean and Orilla, Werhner and Hughes, Patrick M. and Tsai, Susan and Burke, James A. and Wilson, Clive G. (2011) Effects of vitreous liquefaction on the intravitreal distribution of sodium fluorescein, fluorescein dextran and fluorescent microparticles. Investigative Ophthalmology and Visual Science, 52 (2). pp. 1111-1118. ISSN 0146-0404

Weitschies, Werner and Wilson, Clive (2011) In vivo imaging of drug delivery systems in the gastrointestinal tract. International Journal of Pharmaceutics, 417 (1-2). pp. 216-226. ISSN 1873-3476

Miller, Joe and Wilson, W S and Blue, Robert and Wilson, Clive and Uttamchandani, Deepak (2010) Optical fibre coupled ocular spectrometer for measurement of drug concentration in the anterior eye-applications in pharmaceuticals research. IEEE Transactions on Biomedical Engineering, 57 (12). pp. 2903-2909. ISSN 0018-9294

Kek, W.K. and Foulds, Wallace S. and McConnell, Gail and Wright, Amanda and Girkin, John and Wilson, Clive (2010) Two-photon fluorescence excitation microscopy to assess transscleral diffusional pathways in an isolated perfused bovine eye model. Investigative Ophthalmology and Visual Science, 51 (10). pp. 5182-5189. ISSN 0146-0404

Kek, W.K. and Miller, J. and Rawson-Lax, E. and Wilson, C.G. and Uttamchandani, D.G. (2010) In situ measurement of spectral changes in the anterior eye following application of ultraviolet-absorbing compounds. European Journal of Pharmaceutics and Biopharmaceutics, 75 (2). pp. 200-205. ISSN 0939-6411

Goodman, Kirsteen and Hodges, Lee Ann and Band, Janet and Stevens, Howard and Weitschies, Werner and Wilson, Clive (2010) Assessing gastrointestinal motility and disintegration profiles of magnetic tablets by a novel magnetic imaging device and gamma scintigraphy. European Journal of Pharmaceutics and Biopharmaceutics, 74 (1). pp. 84-92. ISSN 0939-6411

McConville, Jason T. and Hodges, Lee Ann and Jones, Tamara and Band, Janet P. and O'Mahony, Bridget and Lindsay, Blythe and Ross, Alistair C. and Florence, Alastair J. and Stanley, Adrian J. and Humphrey, Michael J. and Wilson, Clive and Stevens, Howard (2009) A pharmacoscintigraphic study of three time-delayed capsule formulations in healthy male volunteers. Journal of Pharmaceutical Sciences, 98 (11). pp. 4251-4263. ISSN 0022-3549

Wilson, C. G. and O'Mahony, B. and Connolly, S. M. and Cantarini, M. V. and Farmer, M.R. and Dickinson, P.A. and Smith, R. P. and Swaisland, H.C. (2009) Do gastrointestinal transit parameters influence the pharmacokinetics of gefitinib? International Journal of Pharmaceutics, 376 (1-2). pp. 7-12. ISSN 1873-3476

Hodges, L.A. and Connolly, S.M. and Band, J. and O'Mahony, B. and Ugurlu, T. and Turkoglu, M. and Wilson, C.G. and Stevens, H.N.E. (2009) Scintigraphic evaluation of colon targeting pectin-HPMC tablets in healthy volunteers. International Journal of Pharmaceutics, 370 (1-2). pp. 144-150. ISSN 1873-3476

Couston, R. and McBride, E. and Wilson, C.G. (2009) Preparation of polymeric microspheres as an ophthalmic drug delivery system for brimonidine tartrate. Journal of Pharmacy and Pharmacology, 61 (S1). A22-A23. ISSN 0022-3573

Wilson, Clive and Garbacz, Grzegorz and Wedemeyer, Ralph-Steven and Nagel, Stefan and Giessmann, Thomas and Mönnikes, Hubert and Siegmund, Werner and Weitschiesa, Werner (2008) Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution apparatus that mimics in vivo stresses. European Journal of Pharmaceutics and Biopharmaceutics, 70 (2). pp. 421-428. ISSN 0939-6411

Stokes, R.J. and McBride, E. and Wilson, C.G. and Girkin, J.M. and Smith, W.E. and Graham, D. (2008) Surface-enhanced raman scattering spectroscopy as a sensitive and selective technique for the detection of folic acid in water and human serum. Applied Spectroscopy, 62 (4). pp. 371-376. ISSN 0003-7028

Kossena, Greg A and Charman, William N and Wilson, Clive and O'Mahony, Bridget and Lindsay, Blythe and Hempenstall, John M and Davison, Christopher L and Crowley, Patrick J and Porter, Christopher J. H (2007) Low dose lipid formulations : effects on gastric emptying and biliary secretion. Pharmaceutical Research, 24 (11). pp. 2084-2096. ISSN 0724-8741

McInnes, F.J. and O'Mahony, B. and Lindsay, B. and Band, J. and Wilson, C.G. and Hodges, L.A. and Stevens, H. (2007) Nasal residence of insulin containing lyophilised nasal insert formulations, using gamma scintigraphy. European Journal of Pharmaceutical Sciences, 31 (1). pp. 25-31. ISSN 0928-0987

McBride, E. and Girkin, J.M. and Wilson, C.G. (2006) Automated, real-time monitoring of long-term sustained release delivery. Journal of Pharmacy and Pharmacology, 58. A3-A3. ISSN 0022-3573

Qu, Xioazhong and Khutoryanskiy, Vitaliy V. and Stewart, Ailsa and Rahman, Samina and Papahadjopoulos-Sternberg, Brigitte and Dufès, Christine and McCarthy, Dave and Wilson, Clive G. and Lyons, Robert and Carter, Katharine C. and Schätzlein, Andreas and Uchegbu, Ijeoma F. (2006) Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude. Biomacromolecules, 7 (12). pp. 3452-3459. ISSN 1525-7797

Koeberle, M. and Hughes, P.M. and Skellern, G.G. and Wilson, C.G. (2006) Pharmacokinetics and disposition of memantine in the arterially perfused bovine eye. Pharmaceutical Research, 23. pp. 2781-2798. ISSN 0724-8741

Miller, J. and Wilson, W. S. and Wilson, C.G. and Uttamchandani, D. (2005) Minimally invasive, direct, real time measurement of drug concentration in the anterior eye. British Journal of Ophthalmology, 89 (9). pp. 1147-1151. ISSN 0007-1161

Ingram, P.R. and Pitt, A.R. and Wilson, C.G. and Olejnik, Orest and Spickett, C.M. (2004) A comparison of the effects of ocular preservatives on mammalian and microbial ATP and glutathione levels. Free Radical Research, 38 (7). pp. 739-750. ISSN 1071-5762

Ikinci, Gulcan and Senel, Sevda and Wilson, Clive and Sumnu, Murat (2004) Development of a buccal bioadhesive nicotine tablet formulation for smoking cessation. International Journal of Pharmaceutics, 277 (1-2). pp. 173-178. ISSN 1873-3476

Wilson, Clive (2004) Topical drug delivery in the eye. Experimental Eye Research, 78 (3). pp. 737-743.

Ingram, P.R. and Homer, N.Z.M. and Smith, R.A. and Pitt, A.R. and Wilson, C.G. and Olejnik, O. and Spickett, C.M. (2003) The interaction of sodium chlorite with phospholipids and glutathione: a comparison of effects in vitro, in mammalian and in microbial cells. Archives of Biochemistry and Biophysics, 410 (1). pp. 121-133. ISSN 0003-9861

Koeberle, M. and Hughes, P.M. and Skellern, G.G. and Wilson, C.G. (2003) Binding of memantine to melanin: influence of type of melanin and characteristics. Pharmaceutical Research, 20 (10). pp. 1702-1709. ISSN 0724-8741

Kelly, K. and O'Mahony, B. and Lindsay, B. and Jones, T. and Grattan, T.J. and Rostami-Hodjegan, A. and Stevens, H. and Wilson, C.G. (2003) Comparison of rates of disintegration, gastric emptying, and drug absorption following administration of a new and a conventional paracetamol formulation, using γ scintigraphy. Pharmaceutical Research, 20 (10). pp. 1668-1673. ISSN 0724-8741

Koeberle, M. and Hughes, P.M. and Wilson, C.G. and Skellern, G.G. (2003) Development of a liquid chromatography-mass spectrometric method for the measurement of binding of memantine to different melanins. Journal of Chromatography B, 787 (2). pp. 313-322. ISSN 1570-0232

Miller, J. and Wilson, W. and Kek, W. and Wilson, C.G. and Uttamchandani, D.G. (2003) Drug detection in the living eye using a novel minimally invasive optoelectronic system. IEEE Sensors Journal, 3 (1). pp. 95-101. ISSN 1530-437X

Miller, J. and Wilson, W.S. and Kek, W.K. and Wilson, C.G. and Uttamchandani, D.G. (2003) Spectroscopic detection of a therapeutic drug in the mammalian eye. IEEE Journal of Selected Topics in Quantum Electronics, 9 (2). pp. 171-176. ISSN 1077-260X

Ikinci, Gulcan and Senel, Sevda and Akincibay, H and Kas, Suhela and Ercis, S and Wilson, Clive and Hincal, Attila (2002) Effect of chitosan on a periodontal pathogen porhyromonas gingivalis. International Journal of Pharmaceutics, 235 (1-2). pp. 121-127. ISSN 1873-3476

Wilson, W. and Miller, J. and Wilson, C.G. and Uttamchandani, D.G. (2002) In vivo detection of drugs in the anterior eye. Investigative Ophthalmology and Visual Science, 43 (E-Abst). ISSN 0146-0404

Miller, Joe and Wilson, Clive G. and Uttamchandani, Deepak (2002) Minimally invasive spectroscopic system for intraocular drug detection. Journal of Biomedical Optics, 7 (1). pp. 27-33. ISSN 1083-3668

Martin, L. and Wilson, C.G. and Koosha, F. and Tetley, L. and Gray, A. and Senel, S. and Uchegbu, I.F. (2002) The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels. Journal of Controlled Release, 80 (1-3). pp. 87-100. ISSN 0168-3659

Miller, J. and Wilson, C.G. and Uttamchandani, D.G. (2001) An optoelectronic system for intra-ocular drug detection. Proceedings of SPIE: The International Society for Optical Engineering, 4263 (48). pp. 48-54.

Book Section

Armstrong, Michelle and Walker, Shonagh and Mains, Jenifer and Wilson, Clive; Khutoryanskiy, Vitaliy, ed. (2014) Drug delivery across the nasal mucosa. In: Mucoadhesive Materials and Drug Delivery Systems. John Wiley & Sons, pp. 61-82. ISBN 978-1-119-94143-9

Wilson, Clive; Ratner, Buddy and Hoffman, Allan S. and Schoen, Frederick J. and Lemons, Jack e., eds. (2012) Oral drug delivery. In: Biomaterials Science. Academic Press, pp. 1083-1087. ISBN 9780123746269

Wilson, Clive and Tan, Lay Ean; Alonso, Maria Jose and Csaba, Noemi S. and Thurston, David E. and Martinez, Ana and Fox, David and Rotella, David. P. and Guccione, Salvatore, eds. (2012) Nanostructures overcoming the ocular barrier : physiological considerations and mechanistic issues. In: Nanostructured biomaterials for overcoming biological barriers. RSC Drug Discovery Series . RSC Publishing Ltd, Cambridge, pp. 173-189. ISBN 9781849733632

Wilson, Clive; Sippmann, Juergen and Siegel, Ronald A. and Rathbone, Michael J., eds. (2011) The need for drugs and delivery systems. In: Fundamentals and applications of controlled release drug delivery. Advances in Delivery Science and Technology . Springer, New York, pp. 3-18. ISBN 9781461408802

Wilson, Clive and Tan, Lay Ean and Mains, Jenifer; (2011) Principles of retinal drug delivery from within the vitreous. In: Drug Product Development for the Back of the Eye. AAPS Advances in the Pharmaceutical Sciences Series . Springer, pp. 125-158.