Picture of satellite hovering above Earth

Open Access research exploring new frontiers in aerospace engineering...

Strathprints makes available Open Access scholarly outputs by the Department of Mechanical & Aerospace Engineering at Strathclyde, which includes an emphasis on air and space research. The Advanced Space Concepts Laboratory (ASCL), the Future Air-Space Transportation Technology Laboratory (FASTTlab) and the Intelligent Computational Engineering Laboratory (ICElab) specialise in this work.

The ASCL undertakes frontier research on visionary space systems, delivering radically new approaches to space systems engineering. Meanwhile, FASTTlab seeks to revolutionise the global air-space transportation systems and infrastructure. ICElab develops advanced research on artificial and computational intelligence techniques with particular focus on optimisation, optimal control, uncertainty-based multidisciplinary design optimisation and machine learning applied to the design and control of complex engineering systems.

Learn more and explore the Open Access research by ASCL, FASTTlab and ICElab. Or, explore all of Strathclyde's Open Access research...

Surface-enhanced raman scattering spectroscopy as a sensitive and selective technique for the detection of folic acid in water and human serum

Stokes, R.J. and McBride, E. and Wilson, C.G. and Girkin, J.M. and Smith, W.E. and Graham, D. (2008) Surface-enhanced raman scattering spectroscopy as a sensitive and selective technique for the detection of folic acid in water and human serum. Applied Spectroscopy, 62 (4). pp. 371-376. ISSN 0003-7028

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

Surface-enhanced Raman scattering (SERS) is shown to give linear and sensitive concentration-dependent detection of folic acid using silver nanoparticles created via ethylene-diaminetetraacetic acid (EDTA) reduction. Optical detection by SERS overcomes the primary limitation of photodissociation encountered during the application of other shorter wavelength ultraviolet (UV)/near-UV techniques such as fluorescence based microscopy. The SERS approach in water-based samples was demonstrated and optimized using several longer wavelengths of excitation (514.5, 632.8, and 785 nm). Excitation in the green (514.5 nm) was found to achieve the best balance between photodissociation and SERS efficiency. Linear concentration dependence was observed in the range of 0.018 to 1 lM. The importance of folic acid in a clinical setting and the potential applications of this technique in a biological environment are highlighted. We demonstrate the potential to transfer this technique to real biological samples by the detection of folic acid in human serum samples by SERS. (Abstract from : http://www.opticsinfobase.org/as/abstract.cfm?uri=as-62-4-371)