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Salaun, Christine and Tomkinson, Nicholas C.O. and Chamberlain, Luke H. (2023) The endoplasmic reticulum-localized enzyme zDHHC6 mediates S-acylation of short transmembrane constructs from multiple type I and II membrane proteins. Journal of Biological Chemistry, 299 (10). 105201. ISSN 1083-351X

Butler, Liam and Locatelli, Carolina and Allagioti, Despoina and Lousa, Irina and Lemonidis, Kimon and Tomkinson, Nicholas C. O. and Salaun, Christine and Chamberlain, Luke H. (2023) S-acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme-substrate interaction. Journal of Biological Chemistry, 299 (1). 102754. ISSN 1083-351X

Salaun, Christine and Takizawa, Hiroya and Galindo, Alex and Munro, Kevin R. and McLellan, Jayde and Sugimoto, Isamu and Okino, Tomotaka and Tomkinson, Nicholas C.O. and Chamberlain, Luke H. (2022) Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation. Journal of Biological Chemistry, 298 (10). 102469. ISSN 1083-351X

Valli, Jessica and Garcia-Burgos, Adrian and Rooney, Liam M. and Vale de Melo e Oliveira, Beatriz and Duncan, Rory R. and Rickman, Colin (2021) Seeing beyond the limit : a guide to choosing the right super-resolution microscopy technique. Journal of Biological Chemistry, 297 (1). 100791. ISSN 1083-351X

Brown, Ryan D.R. and Veerman, Ben E.P. and Oh, Jeongah and Tate, Rothwelle J. and Torta, Federico and Cunningham, Margaret R. and Adams, David R. and Pyne, Susan and Pyne, Nigel J. (2021) A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells. Journal of Biological Chemistry. 100674. ISSN 1083-351X

Zmuda, Filip and Chamberlain, Luke H. (2020) Regulatory effects of post-translational modifications on zDHHC S-acyltransferases. Journal of Biological Chemistry, 295 (43). pp. 14640-14652. ISSN 1083-351X

Katsikoudi, Antigoni and Ficulle, Elena and Cavallini, Annalisa and Sharman, Gary and Guyot, Amelie and Zagnoni, Michele and Eastwood, Brian J. and Hutton, Michael and Bose, Suchira (2020) Quantitative propagation of assembled human Tau from Alzheimer's disease brain in microfluidic neuronal cultures. Journal of Biological Chemistry, 295 (37). pp. 13079-13093. ISSN 1083-351X

Salaun, Christine and Greaves, Jennifer and Tomkinson, Nicholas C. O. and Chamberlain, Luke H. (2020) The linker domain of the SNARE protein SNAP25 acts as a flexible molecular spacer that ensures efficient S-acylation. Journal of Biological Chemistry, 295 (21). pp. 7501-7515. ISSN 1083-351X

Radhi, Ohood A. and Davidson, Scott and Scott, Fiona and Zeng, Run X. and Jones, D. Heulyn and Tomkinson, Nick C. O. and Yu, Jun and Chan, Edmond Y.W. (2019) Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death. Journal of Biological Chemistry, 294. pp. 14289-14307. ISSN 1083-351X

Wilson, Calum and Lee, Matthew D. and Heathcote, Helen R. and Zhang, Xun and Buckley, Charlotte and Girkin, John M. and Saunter, Christopher D. and McCarron, John G. (2019) Mitochondrial ATP production provides long-range control of endothelial inositol trisphosphate–evoked calcium signaling : mitochondrial control of endothelial Ca2+ signaling. Journal of Biological Chemistry, 294 (3). pp. 737-758. ISSN 1083-351X

Buckley, Charlotte and Nelson, Robert J. and Mullins, Linda J. and Sharp, Matthew G. F. and Fleming, Stewart and Kenyon, Christopher J. and Semprini, Sabrina and Steppan, Dominik and Peti-Peterdi, Janos and Kurtz, Armin and Christian, Helen and Mullins, John J. (2018) Phenotypic dissection of the mouse Ren1d knockout by complementation with human renin. Journal of Biological Chemistry, 293 (4). pp. 1151-1162. ISSN 1083-351X

Lemonidis, Kimon and MacLeod, Ruth and Baillie, George S. and Chamberlain, Luke H. (2017) Peptide array–based screening reveals a large number of proteins interacting with the ankyrin-repeat domain of the zDHHC17 S-acyltransferase. Journal of Biological Chemistry, 292 (42). pp. 17190-17202. ISSN 1083-351X

Ahmed, Umul Kulthum and Maller, N. Claire and Iqbal, Asif J. and Al-Riyami, Lamyaa and Harnett, William and Raynes, John G. (2016) The carbohydrate-linked phosphorylcholine of the parasitic nematode product ES-62 modulates complement activation. Journal of Biological Chemistry, 291 (22). pp. 11939-11953. ISSN 1083-351X

Grewal, Jaspreet S. and McLuskey, Karen and Das, Debanu and Myburgh, Elmarie and Wilkes, Jonathan and Brown, Elaine and Lemgruber, Leandro and Gould, Matthew K. and Burchmore, Richard J. and Coombs, Graham H. and Schnaufer, Achim and Mottram, Jeremy C. (2016) PNT1 is a C11 cysteine peptidase essential for replication of the trypanosome kinetoplast. Journal of Biological Chemistry, 291 (18). pp. 9492-9500. ISSN 1083-351X

McLuskey, Karen and Grewal, Jaspreet S. and Das, Debanu and Godzik, Adam and Lesley, Scott A. and Deacon, Ashley M. and Coombs, Graham H. and Elsliger, Marc-André and Wilson, Ian A. and Mottram, Jeremy C. (2016) Crystal structure and activity studies of the C11 cysteine peptidase from parabacteroides merdae in the human gut microbiome. Journal of Biological Chemistry, 291 (18). pp. 9482-9491. ISSN 1083-351X

Lemonidis, Kimon and Sanchez-Perez, Maria C. and Chamberlain, Luke H. (2015) Identification of a novel sequence motif recognised by the ankyrin-repeat domain of zDHHC17/13 S-acyl-transferases. Journal of Biological Chemistry. ISSN 1083-351X

Sommerville, Caroline and Richardson, Julia M and Williams, Roderick A M and Mottram, Jeremy C and Roberts, Craig W and Alexander, James and Henriquez, Fiona L (2013) Biochemical and immunological characterization of Toxoplasma gondii macrophage migration inhibitory factor. Journal of Biological Chemistry, 288 (18). pp. 12733-12741. ISSN 1083-351X

Williams, Roderick A M and Mottram, Jeremy C and Coombs, Graham H (2013) Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of Leishmania major. Journal of Biological Chemistry, 288 (5). pp. 3678-3690. ISSN 1083-351X

Harling, John D and Deakin, Angela M and Campos, Sébastien and Grimley, Rachel and Chaudry, Laiq and Nye, Catherine and Polyakova, Oxana and Bessant, Christina M and Barton, Nick and Somers, Don and Barrett, John and Graves, Rebecca H and Hanns, Laura and Kerr, W. J. and Solari, Roberto (2013) Discovery of novel irreversible inhibitors of IL-2 inducible tyrosine kinase (Itk) by targeting cysteine 442 in the ATP pocket. Journal of Biological Chemistry (39). pp. 28195-28206. ISSN 1083-351X

Greaves, Jennifer and Lemonidis, Kimon and Gorleku, Oforiwa and Cruchaga, Carlos and Grefen, Christopher and Chamberlain, Luke (2012) Palmitoylation-induced aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis. Journal of Biological Chemistry, 287 (44). pp. 37330-37339. ISSN 1083-351X

Bar-On, Dana and Wolter, Steve and van de Linde, Sebastian and Heilemann, Mike and Nudelman, German and Nachliel, Esther and Gutman, Menachem and Sauer, Markus and Ashery, Uri (2012) Super-resolution imaging reveals the internal architecture of nano-sized syntaxin clusters. Journal of Biological Chemistry, 287 (32). pp. 27158-27167. ISSN 1083-351X

Nisar, Shaista P and Cunningham, Margaret and Saxena, Kunal and Pope, Robert J and Kelly, Eamonn and Mundell, Stuart J (2012) Arrestin scaffolds NHERF1 to the P2Y12 receptor to regulate receptor internalization. Journal of Biological Chemistry, 287 (29). pp. 24505-24515. ISSN 1083-351X

Cunningham, Margaret R. and McIntosh, Kathryn A. and Pediani, John D. and Robben, Joris and Cooke, Alexandra E. and Nilsson, Mary and Gould, Gwyn W. and Mundell, Stuart and Milligan, Graeme and Plevin, Robin (2012) Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4). Journal of Biological Chemistry, 287 (20). pp. 16656-16669. ISSN 1083-351X

Gorleku, Oforiwa A and Barns, Anna-Marie and Prescott, Gerald R and Greaves, Jennifer and Chamberlain, Luke H (2011) Endoplasmic reticulum localization of DHHC palmitoyltransferases mediated by lysine-based sorting signals. Journal of Biological Chemistry, 286. pp. 39573-39584. ISSN 1083-351X

Compton-Daw, Emma and Karinou, Eleni and Naismith, James H. and Gabel, Frank and Javelle, Arnaud (2011) Low resolution structure of a bacterial SLC26 transporter reveals dimeric stoichiometry and mobile intracellular domains. Journal of Biological Chemistry, 286 (30). pp. 27058-27067. ISSN 1083-351X

Lim, Keng and Tonelli, Francesca Romana and Li, Z. and Lu, X. and Bittman, R. and Pyne, Susan and Pyne, Nigel (2011) FTY720 analogues as sphingosine kinase 1 inhibitors : enzyme inhibition kinetics, allosterism, proteasomal degradation and actin rearrangement in MCF-7 breast cancer cells. Journal of Biological Chemistry, 286 (21). pp. 18633-18640. ISSN 1083-351X

Lawan, Ahmed and Al-Harthi, Sameer and Cadalbert, Laurence and McCluskey, Anthony G. and Shweash, Muhannad and Grassia, Gianluca and Grant, Anne and Boyd, Marie and Currie, Susan and Plevin, Robin (2011) Deletion of the dual specific phosphatase-4 (DUSP-4) gene reveals an essential non-redundant role for MAP kinase phosphatase-2 (MKP-2) in proliferation and cell survival. Journal of Biological Chemistry, 286 (15). pp. 12933-12943. ISSN 1083-351X

Proto, William R and Castanys-Munoz, Esther and Black, Alana and Tetley, Laurence and Moss, Catherine X and Juliano, Luiz and Coombs, Graham H and Mottram, Jeremy C (2011) Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor. Journal of Biological Chemistry. ISSN 1083-351X

Loveridge, Carolyn and Tonelli, Francesca and Leclercq, Tamara and Lim, Keng Gat and Long, Jaclyn S and Berdyshev, Evgeny and Tate, Rothwelle J and Natarajan, Viswanathan and Pitson, Stuart M and Pyne, Nigel J and Pyne, Susan (2010) The sphingosine kinase 1 inhibitor 2-(P-hydroxyanilino)-4-(P-chlorophenyl)thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells. Journal of Biological Chemistry, 285 (50). pp. 38841-38852. ISSN 1083-351X

Long, J.S. and Fujiwara, Y. and Edwards, J. and Tannahill, C.L. and Tigyi, G. and Pyne, S. and Pyne, N.J. (2010) Sphingosine 1-phosphate receptor 4 uses HER2 (ErbB2) to regulate extracellular signal regulated kinase-1/2 in MDA-MB-453 breast cancer cells. Journal of Biological Chemistry, 285. pp. 35957-35966. ISSN 1083-351X

Greaves, Jennifer and Gorleku, Oforiwa A and Salaun, Christine and Chamberlain, Luke H (2010) Palmitoylation of the SNAP25 protein family : specificity and regulation by DHHC palmitoyl transferases. Journal of Biological Chemistry, 285 (32). pp. 24629-24638. ISSN 1083-351X

Rickman, Colin and Medine, Claire N and Dun, Alison R and Moulton, David J and Mandula, Ondrej and Halemani, Nagaraj D and Rizzoli, Silvio O and Chamberlain, Luke H and Duncan, Rory R (2010) t-SNARE protein conformations patterned by the lipid microenvironment. Journal of Biological Chemistry, 285 (18). pp. 13535-13541. ISSN 1083-351X

Olson, M. and Chalmers, S. and McCarron, John G. (2010) Mitochondrial Ca2+ uptake increases Ca2+ release from Inositol 1,4,5-trisphosphate receptor clusters in smooth muscle cells. Journal of Biological Chemistry, 285 (3). pp. 2040-2050. ISSN 1083-351X

May, Victor and Lutz, E. and MacKenzie, C. and Schutz, Kirstin C. and Dozark, Kate and Braas, Karen M. (2010) Pituitary adenylate cyclase activating polypeptide (PACAP)/PAC1-HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through PI3K and vesicle endocytosis for neuronal survival. Journal of Biological Chemistry, 285 (13). pp. 9749-9761. ISSN 1083-351X

Westrop, G.D. and Georg, I. and Coombs, G.H. (2009) The mercaptopyruvate sulfurtransferase of trichomonas vaginalis links cysteine catabolism to the production of thioredoxin persulfide. Journal of Biological Chemistry, 284 (48). pp. 33485-33494. ISSN 1083-351X

Li, Xiang and Baillie, George and Houslay, Miles (2009) Mdm2 directs the ubiquitination of β-arrestin-sequestered cAMP phosphodiesterase-4D5. Journal of Biological Chemistry, 284 (24). pp. 16170-16182. ISSN 1083-351X

Babich, Victor and Knipe, Laura and Hewlett, Lindsay and Meli, Athinoula and Dempster, J. and Hannah, Matthew J. and Carter, Tom (2009) Differential effect of extracellular acidosis on the release and dispersal of soluble and membrane proteins secreted from the weibel-palade body. Journal of Biological Chemistry, 284 (18). pp. 12459-12468. ISSN 1083-351X

Smith, W.E. and Lewis, D.G. and Dunford, A.J. and Seward, H.E. and Neeli, R. and Cheesman, M.R. and Marsollier, L. (2008) Characterization of active site structure in cyp121 a cytochrome p450 essential for viability of mycobacterium tuberculosis h37rv. Journal of Biological Chemistry, 283 (48). pp. 33406-33416. ISSN 1083-351X

Greaves, Jennifer and Salaun, Christine and Fukata, Yuko and Fukata, Masaki and Chamberlain, Luke H (2008) Palmitoylation and membrane interactions of the neuroprotective chaperone cysteine-string protein. Journal of Biological Chemistry, 283 (36). pp. 25014-25026. ISSN 1083-351X

Erridge, Clett and Kennedy, S. and Spickett, C.M. and Webb, David J. (2008) Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4 roles for cd14, lps-binding protein, and md2 as targets for specificity of inhibition. Journal of Biological Chemistry, 283, Issu (36). pp. 24748-24759. ISSN 1083-351X

Gorshkova, Irina and He, Donghong and Berdyshev, Evgeny and Usatuyk, Peter and Burns, Michael and Kalari, Satish and Zhao, Yutang and Pendyala, Srikanth and Garcia, Joe G.N. and Pyne, N.J. and Brindley, David N. and Natarajan, Viswanathan (2008) Protein kinase C-epsilon regulates sphingosine-1-phosphate-mediated migration of human lung endothelial cells through activation of phospholipase D2, protein Kinase C-zeta, and Rac1. Journal of Biological Chemistry, 283 (17). pp. 11794-11806. ISSN 1083-351X

McCarron, J.G. and Olson, Marnie (2008) A single luminally continuous sarcoplasmic reticulum with apparently separate Ca2+ stores in smooth muscle. Journal of Biological Chemistry, 283 (11). pp. 7206-7218. ISSN 1083-351X

Rentmeister, Andrea and Mayer, G. and Kuhn, Nicole and Famulok, Michael (2008) Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides. Journal of Biological Chemistry, 389 (2). pp. 127-134. ISSN 1083-351X

Tucker, Nick and D'Autréaux, Benoît and Yousafzai, Faridoon K. and Fairhurst, Shirley A. and Spiro, Stephen and Dixon, Ray (2008) Analysis of the nitric oxide-sensing non-heme iron center in the NorR regulatory protein. Journal of Biological Chemistry, 283 (2). pp. 908-918. ISSN 1083-351X

Walker, Daniel and Mosbahi, Khédidja and Vankemmelbeke, Mireille and James, Richard and Kleanthous, Colin (2007) The role of electrostatics in colicin nuclease domain translocation into bacterial cells. Journal of Biological Chemistry, 282 (43). pp. 31389-31397. ISSN 1083-351X

Lyon, R.C. and Johnston, S.M. and Watson, D.G. and McGarvie, G. and Ellis, E.M. (2007) Synthesis and catabolism of gamma-hydroxybutyrate in SH-SY5Y human neuroblastoma cells. Journal of Biological Chemistry, 282 (36). pp. 25986-25992. ISSN 1083-351X

Chan, Edmond Y W and Kir, Serkan and Tooze, Sharon A (2007) siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy. Journal of Biological Chemistry, 282 (35). pp. 25464-25474. ISSN 1083-351X

Kleczka, B. and Lamerz, Anne-Christin and van Zandbergen, G. and Wenzel, Ulf and Gerardy-Schahn, Rita and Wiese, Martin and Routier, Françoise H (2007) Targeted gene deletion of leishmania major UDP-galactopyranose mutase leads to attenuated virulence. Journal of Biological Chemistry, 282 (14). pp. 10498-10505. ISSN 1083-351X

Herz, Corinna and Aumailley, Monique and Schulte, Carsten and Schlötzer-Schrehardt, Ursula and Bruckner-Tuderman, Leena and Has, Cristina (2006) Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes. Journal of Biological Chemistry, 281 (47). pp. 36082-36090. ISSN 1083-351X

Franzke, Claus Werner and Has, Cristina and Schulte, Carsten and Huilaja, Laura and Tasanen, Kaisa and Aumailley, Monique and Bruckner-Tuderman, Leena (2006) C-terminal truncation impairs glycosylation of transmembrane collagen XVII and leads to intracellular accumulation. Journal of Biological Chemistry, 281 (40). pp. 30260-30268. ISSN 1083-351X

Westrop, G.D. and Goodall, Gordon and Mottram, Jeremy C. and Coombs, G.H. (2006) Cysteine biosynthesis in trichomonas vaginalis involves cysteine synthase utilizing o-phosphoserine. Journal of Biological Chemistry, 281 (35). pp. 25062-25075. ISSN 1083-351X

Zhao, Y. and He, D. and Saatian, B. and Watkins, T. and Spannhake, E.W. and Pyne, N.J. and Natarajan, V. (2006) Regulation of lysophosphatidic acid-induced epidermal growth factor receptor transactivation and interleukin-8 secretion in human bronchial epithelial cells by protein kinase cdelta, lyn kinase, and matrix metalloproteinases. Journal of Biological Chemistry, 281 (28). pp. 19501-19511. ISSN 1083-351X

Besteiro, S. and Williams, R.A. and Morrison, L.S. and Coombs, G.H. and Mottram, J.C. (2006) Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major. Journal of Biological Chemistry, 281 (16). pp. 11384-11396. ISSN 1083-351X

Sorrell, A.M. and Shand, J.H. and Tonner, E. and Gamberoni, M. and Accorsi, P.A. and Beattie, J. and Allan, G.J. and Flint, D.J. (2006) Insulin-like growth factor-binding protein-5 activates plasminogen by interaction with tissue plasminogen activator, independently of its ability to bind to plasminogen activator inhibitor-1, insulin-like growth factor-I, or heparin. Journal of Biological Chemistry, 281 (16). pp. 10883-10889. ISSN 1083-351X

Peric-Concha, Nataša and Borovicka, Branko and Long, Paul F. and Hranueli, Daslav and Waterman, Peter G. and Hunter, Iain S. (2005) Ablation of the OtcC gene encoding a post-polketide hydroxylase from the oxytetracyline biosynthetic pathway in streptomyces rimosus results in novel polyketides with altered chain length. Journal of Biological Chemistry, 280. pp. 37455-37460. ISSN 1083-351X

Broderick, Kate E and Kean, Laura and Dow, Julian A T and Pyne, Nigel J and Davies, Shireen A (2004) Ectopic expression of bovine type 5 phosphodiesterase confers a renal phenotype in Drosophila. Journal of Biological Chemistry, 279 (9). pp. 8159-8168. ISSN 1083-351X

Altroff, H. and Schlinkert, R. and Van Der Walle, C.F. and Bernini, A. and Campbell, I.D. and Werner, J.M. and Mardon, H.J. (2004) Interdomain tilt angle determines integrin-dependent function of the ninth and tenth fIII domains of human fibronectin. Journal of Biological Chemistry, 279. pp. 5995-6003. ISSN 1083-351X

Delon, C. and Manifava, M. and Wood, E. and Thompson, D. and Krugmann, S. and Pyne, S. and Ktistakis, N.T. (2004) Sphingosine kinase 1 is an intracellular effector of phosphatidic acid. Journal of Biological Chemistry, 279. pp. 44763-44774. ISSN 1083-351X

McCarron, J.G. and MacMillan, D. and Bradley, K.N. and Chalmers, S. and Muir, T.C. (2004) Origin and mechanisms of Ca2+ waves in smooth muscle as revealed by localized photolysis of caged inositol 1,4,5-trisphosphate. Journal of Biological Chemistry, 279. pp. 8417-8427. ISSN 1083-351X

Mitchell, R. and Robertson, D.N. and Holland, P.J. and Collins, D. and Lutz, E.M. and Johnson, M.S. (2003) ADP-ribosylation factor-dependent phospholipase D activation by the M-3 muscarinic receptor. Journal of Biological Chemistry, 278 (36). pp. 33818-33830. ISSN 1083-351X

Alphey, Magnus S. and Williams, Roderick and Mottram, Jeremy and Coombs, Graham and Hunter, William N. (2003) The crystal structure of Leishmania major 3-mercaptopyruvate sulfurtransferase : A three-domain architecture with a serine protease-like triad at the active site. Journal of Biological Chemistry, 278. pp. 48219-48227. ISSN 1083-351X

Chalmers, Susan and Nicholls, David (2003) The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria. Journal of Biological Chemistry, 278 (21). pp. 19062-19070. 12660243. ISSN 1083-351X

Shand, J.H. and Beattie, J. and Flint, D.J. and Song, H. and Allan, G.J. and Phillips, K. and Kelly, S.M. (2003) Specific amino acid substitutions determine the differential contribution of the N- and C-terminal domains of insulin-like growth factor (IGF)-binding protein-5 in binding IGF-I. Journal of Biological Chemistry, 278 (20). pp. 17859-17866. ISSN 1083-351X

Waters, C.M. and Sambi, B. and Kong, K.C. and Thompson, Dawn and Pitson, S.M. and Pyne, S. and Pyne, N.J. (2003) Sphingosine 1-phosphate and platelet-derived growth factor (pdgf) act via pdgf beta receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cells. Journal of Biological Chemistry, 278 (8). pp. 6282-6290. ISSN 1083-351X

Williams, Roderick and Kelly, Sharon and Mottram, Jeremy and Coombs, Graham (2003) 3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism. Journal of Biological Chemistry, 278. pp. 1480-1486. ISSN 1083-351X

Wan, K.F. and Sambi, B.S. and Tate, R. and Waters, C. and Pyne, N.J. (2003) The inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and g-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated protein kinase by epidermal growth factor. Journal of Biological Chemistry, 278. pp. 18658-18663. ISSN 1083-351X

Garofalo, A. and Rowlinson, M. and Amambua, N. and Hughes, J.M. and Kelly, S.M. and Price, N. and Cooper, A. and Watson, D.G. and Kennedy, M.W. and Bradley, J.E. (2002) The FAR protein family of the nematode caenorhabditis elegans: differential lipid binding properties, structural characteristics, and developmental regulation. Journal of Biological Chemistry, 278 (10). pp. 8065-8074. ISSN 1083-351X

Kozma, E. and Brown, E. and Ellis, E. and Lapthorn, A. (2002) The crystal structure of rat liver AKR7A1: a dimeric member of the Aldo-Keto reductase superfamily. Journal of Biological Chemistry, 277 (18). pp. 16285-16293. ISSN 1083-351X

Downie, D.L. and Vicente-Agullo, F. and Campos-Caro, A. and Bushell, T. and Lieb, W.R. and Franks, N.P. (2002) Determinants of the anesthetic sensitivity of neuronal nicotinic acetylcholine receptors. Journal of Biological Chemistry, 277. pp. 10367-10373. ISSN 1083-351X

Flynn, Elaine R.M. and Bradley, Karen N. and Muir, Thomas C. and McCarron, John G. (2001) Functionally-separate intracellular ca2+ stores in smooth muscle. Journal of Biological Chemistry, 276. pp. 36411-18. ISSN 1083-351X

Alderton, Forbes and Darroch, Peter and Sambi, Balwinder and McKie, Amanda and Ahmed, Ikhlas Said and Pyne, Nigel and Pyne, Susan (2001) G-protein-coupled receptor stimulation of the p42/p44 mitogen-activated protein kinase pathway is attenuated by liPID phosphate phosphatases 1, 1a, and 2 in human embryonic kidney 293 cells. Journal of Biological Chemistry, 276. pp. 13452-13460. ISSN 1083-351X

Alderton, Forbes and Rakhit, Soma and Kong, Kok Choi and Palmer, Timothy and Sambi, Balwinder and Pyne, Nigel and Pyne, Susan (2001) Tethering of the platelet-derived growth factor beta receptor to g-protein-coupled receptors : a novel platform for integrative signaling by these receptor classes in mammalian cells. Journal of Biological Chemistry, 276. pp. 28578-28585. ISSN 1083-351X

Altroff, Harri and Van Der Walle, Christopher F. and Asselin, Judith and Fairless, Richard and Campbell, Iain D. and Mardon, Helen J. (2001) The eighth fIII domain of human fibronectin promotes integrin alpha5beta1 binding via stabilization of the ninth fIII domain. Journal of Biological Chemistry, 276. pp. 38885-38892. ISSN 1083-351X

Kanke, T. and MacFarlane, S.R. and Seatter, M.J. and Davenport, E.L. and Paul, A. and McKenzie, R.C. and Plevin, R.J. (2001) Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa b kinases in NCTC 2544 keratinocytes. Journal of Biological Chemistry, 276 (34). pp. 31657-31666. ISSN 1083-351X

Wan, K.F. and Sambi, B.S. and Frame, M.J. and Tate, R. and Pyne, N.J. (2001) The inhibitory gamma subunit of the type 6 retinal cyclic guanosine monophosphate phosphodiesterase is a novel intermediate regulating p42/p44 mitogen-activated protein kinase signaling in human embryonic kidney 293 cells. Journal of Biological Chemistry, 276 (41). pp. 37794-37802. ISSN 1083-351X

Huston, Elaine and Beard, Matthew and McCallum, Fraser and Pyne, Nigel J. and Vandenabeele, Peter and Scotland, Grant and Houslay, Miles D. (2000) The cAMP-specific phosphodiesterase PDE4A5 is cleaved downstream of its SH3 interaction domain by caspase-3 : consequences for altered intracellular distribution. Journal of Biological Chemistry, 275 (36). pp. 28063-28074. ISSN 1083-351X

Alessandri-Haber, N. and Lecoq, A. and Gasparini, S. and Grangier-Macmath, G. and Jacquet, G. and Harvey, Alan L. and de Medeiros, C. and Rowan, Edward G. and Gola, M. and Ménez, A. and Crest, M. (1999) Mapping the functional anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. : Clues to design analogs with enhanced selectivity. Journal of Biological Chemistry, 274 (50). pp. 35653-35661. ISSN 1083-351X

Gasparini, S. and Danse, J.M. and Lecoq, A. and Pinkasfeld, S. and Zinn-Justin, S. and Young, L.C. and de Medeiros, C.C.L. and Rowan, E.G. (1998) Delineation of the functional site of alpha-dendrotoxin - the functional topographies of dendrotoxins are different but share a conserved core with those of other kv1 potassium channel-blocking toxins. Journal of Biological Chemistry, 273 (39). pp. 25393-25403. ISSN 1083-351X

Davies, Ben J. and Pickard, Benjamin S. and Steel, Muriel and Morris, Richard G. M. and Lathe, Richard (1998) Serine proteases in rodent hippocampus. Journal of Biological Chemistry, 273. pp. 23004-23011. ISSN 1083-351X

Daniels, Michael J. and Turner-Cavet, Jennifer S. and Selkirk, Richard and Sun, Hongzhe and Parkinson, John and Sadler, Peter J. (1998) Coordination of Zn2+ (and Cd2+) by prokaryotic metallothionein : involvement of His-imidazole. Journal of Biological Chemistry, 273 (36). pp. 22957-22961. ISSN 1083-351X

Ivanov, Andrei I. and Christodoulou, John and Parkinson, John A. and Barnham, Kevin J. and Tucker, Alan and Woodrow, John and Sadler, Peter J. (1998) Cisplatin binding sites on human albumin. Journal of Biological Chemistry, 273 (24). pp. 14721-14730. ISSN 1083-351X

Lochhead, A and Nekrasova, E and Arshavsky, V Y and Pyne, N J (1997) The regulation of the cGMP-binding cGMP phosphodiesterase by proteins that are immunologically related to gamma subunit of the photoreceptor cGMP phosphodiesterase. Journal of Biological Chemistry, 272 (29). pp. 18397-18403. ISSN 1083-351X

Dauplais, M. and Lecoq, A. and Song, J.X. and Cotton, J. and Jamin, N. and Gilquin, B. and Rowan, E.G. and Vita, C. (1997) On the convergent evolution of animal toxins - conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures. Journal of Biological Chemistry, 272 (7). pp. 4302-4309. ISSN 1083-351X

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