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Mathis, Thibaud and Baudin, Florian and Mariet, Anne-Sophie and Augustin, Sébastien and Bricout, Marion and Przegralek, Lauriane and Roubeix, Christophe and Benzenine, Éric and Blot, Guillaume and Nous, Caroline and Kodjikian, Laurent and Mauget-Faÿsse, Martine and Sahel, José-Alain and Plevin, Robin and Zeitz, Christina and Delarasse, Cécile and Guillonneau, Xavier and Creuzot-Garcher, Catherine and Quantin, Catherine and Hunot, Stéphane and Sennlaub, Florian (2024) DRD2 activation inhibits choroidal neovascularization in patients with Parkinson's disease and age-related macular degeneration. Journal of Clinical Investigation, 134 (17). e174199. ISSN 0021-9738

Riley, Christopher and Ammar, Usama and Alsfouk, Aisha and Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Breen, David and Huggan, Judith and Lawson, Christopher and McIntosh, Kathryn and Plevin, Robin and Suckling, Colin J. and Young, Louise C. and Paul, Andrew and Mackay, Simon P. (2024) Design and synthesis of novel aminoindazole-pyrrolo[2,3-b]pyridine inhibitors of IKKα that selectively perturb cellular non-canonical NF-κB signalling. Molecules, 29 (15). 3515. ISSN 1420-3049

McIntosh, Kathryn and Khalaf, Yousif H. and Craig, Rachel and West, Christopher and McCulloch, Ashley and Waghmare, Ajay and Lawson, Christopher and Chan, Edmond Y.W. and MacKay, Simon and Paul, Andrew and Plevin, Robin (2023) IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling. Cellular Signalling, 107. 110684. ISSN 1873-3913

Patkar, Shalmali and Uwanogho, Dafe and Modo, Michel and Tate, Rothwelle J. and Plevin, Robin and Carswell, Hilary V. O. (2022) Targeting 17β-estradiol biosynthesis in neural stem cells improves stroke outcome. Frontiers in Cellular Neuroscience, 16. 917181. ISSN 1662-5102

McIntosh, Kathryn A. and Cunningham, Margaret R. and Bushell, Trevor and Plevin, Robin (2020) The development of proteinase-activated receptor-2 modulators and the challenges involved. Biochemical Society Transactions, 48 (6). pp. 2525-2537. BST20200191. ISSN 0300-5127

Montes, Melania and MacKenzie, Lewis and McAllister, Milly J. and Roseweir, Antonia and McCall, Pamela and Hatziieremia, Sophia and Underwood, Mark A. and Boyd, Marie and Paul, Andrew and Plevin, Robin and MacKay, Simon P. and Edwards, Joanne (2020) Determining the prognostic significance of IKKα in prostate cancer. The Prostate, 80 (14). pp. 1188-1202. ISSN 1097-0045

Pytka, Karolina and Dawson, Neil and Tossell, Kyoko and Ungless, Mark A. and Plevin, Robin and Brett, Ros R. and Bushell, Trevor J. (2020) Mitogen‐activated protein kinase phosphatase‐2 deletion modifies ventral tegmental area function and connectivity and alters reward processing. European Journal of Neuroscience, 52 (2). pp. 2838-2852. ISSN 0953-816X

Abdel-Ghani, Lougin M. and Rahmy, Tarek R. and Tawfik, Mohamed M. and Kaziri, Ibtisam and Al-Obaidi, Ahlam and Rowan, Edward G. and Plevin, Robin and Abdel-Rahman, Mohamed A. (2019) Cytotoxicity of Nubein6.8 peptide isolated from the snake venom of Naja nubiae on melanoma and ovarian carcinoma cell lines. Toxicon, 168. pp. 22-31. ISSN 1879-3150

Neamatallah, Thikryat and Jabbar, Shilan and Tate, Rothwelle and Schroeder, Juliane and Shweash, Muhannad and Alexander, James and Plevin, Robin (2019) Whole genome microarray analysis of DUSP4-deletion reveals a novel role for MAP kinase phosphatase-2 (MKP-2) in macrophage gene expression and function. International Journal of Molecular Sciences, 20 (14). 3434. ISSN 1422-0067

Schroeder, Juliane and Ross, Kirsty and McIntosh, Kathryn and Jabbar, Shilan Khayrula Jabbar and Woods, Stuart and Crowe, Jenny and Patterson-Kane, Janet C and Alexander, James and Lawrence, Catherine and Plevin, Robin (2019) Novel protective role for MAP kinase phosphatase 2 in inflammatory arthritis. RMD Open, 5 (1). e000711. e000711. ISSN 2056-5933

Ng, Pei Y. and McIntosh, Kathryn A. and Hargrave, Gillian and Ho, Ka H. and Paul, Andrew and Plevin, Robin (2018) Inhibition of cytokine-mediated JNK signalling by purinergic P2Y11 receptors, a novel protective mechanism in endothelial cells. Cellular Signalling, 51. pp. 59-71. ISSN 1873-3913

Chen, Ming and Zhang, Jiangwen and Berger, Alice H. and Diolombi, Moussa S. and Ng, Christopher and Fung, Jacqueline and Bronson, Roderick T. and Castillo-Martin, Mireia and Thin, Tin Htwe and Cordon-Cardo, Carlos and Plevin, Robin and Pandolfi, Pier Paolo (2018) Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis. Journal of Clinical Investigation, 129 (1). pp. 215-222. ISSN 0021-9738

Choi, Jason C and Wu, Wei and Phillips, Elizabeth and Plevin, Robin and Sera, Fusako and Homma, Shunichi and Worman, Howard J (2018) Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival. Human Molecular Genetics, 27 (13). pp. 2290-2305. ISSN 0964-6906

Wood, Rachel A. and Barbour, Mark J. and Gould, Gwyn W. and Cunningham, Margaret R. and Plevin, Robin J. (2018) Conflicting evidence for the role of JNK as a target in breast cancer cell proliferation : comparisons between pharmacological inhibition and selective shRNA knockdown approaches. Pharmacology Research & Perspectives, 6 (1). ISSN 2052-1707

Wilkinson, David J. and Desilets, Antoine and Lin, Hua and Charlton, Sarah and Del Carmen Arques, Maria and Falconer, Adrian and Bullock, Craig and Hsu, Yu Chen and Birchall, Kristian and Hawkins, Alastair and Thompson, Paul and Ferrell, William R. and Lockhart, John and Plevin, Robin and Zhang, Yadan and Blain, Emma and Lin, Shu Wha and Leduc, Richard and Milner, Jennifer M. and Rowan, Andrew D. (2017) The serine proteinase hepsin is an activator of pro-matrix metalloproteinases : molecular mechanisms and implications for extracellular matrix turnover. Scientific Reports, 7 (1). 16693. ISSN 2045-2322

Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Boyd, Marie and Breen, David and Edwards, Joanne and Gamble, Carly and Gray, Alexander I. and Harvey, Alan L. and Hatziieremia, Sophia and Ho, Ka Ho and Huggan, Judith K. and Lang, Stuart and Llona-Minguez, Sabin and Luo, Jia Lin and McIntosh, Kathryn and Paul, Andrew and Plevin, Robin J. and Robertson, Murray N. and Scott, Rebecca and Suckling, Colin J. and Sutcliffe, Oliver Brook and Young, Louise C. and MacKay, Simon P. (2017) Inhibitory Kappa B kinase α (IKKα) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers. Journal of Medicinal Chemistry, 60 (16). pp. 7043-7066. ISSN 0022-2623

Coats, P and Plevin, R and Burzangi, A (2017) Mitochondria has a role in regulating hypoxic-dependent cell proliferation in pulmonary cells and vascular remodelling. Heart, 103 (Suppl ). A6-A7. ISSN 1468-201X

White, S. and Plevin, R. and Zagnoni, M. and Carswell, H. (2017) An in vitro microfluidic model of microglia migration after stroke. Journal of Cerebral Blood Flow and Metabolism, 37 (1 (Sup). ISSN 0271-678X

Barbour, Mark and Plevin, Robin and Jiang, Hui-Rong (2016) MAP kinase phosphatase 2 deficient mice develop attenuated experimental autoimmune encephalomyelitis through regulating dendritic cells and T cells. Scientific Reports, 6. pp. 1-13. 38999. ISSN 2045-2322

Cunningham, Margaret and McIntosh, Kathryn and Bushell, Trevor and Sloan, Graeme and Plevin, Robin (2016) Proteinase-activated receptors (PARs) as targets for antiplatelet therapy. Biochemical Society Transactions, 44 (2). pp. 606-612. ISSN 0300-5127

Abdul Rahman, Nor Zaihana Binti and Greenwood, Sam M. and Brett, Ros R. and Tossell, Kyoko and Ungless, Mark A. and Plevin, Robin and Bushell, Trevor J. (2016) Mitogen-activated protein kinase phosphatase-2 deletion impairs synaptic plasticity and hippocampal-dependent memory. Journal of Neuroscience, 36 (8). pp. 2348-2354. ISSN 0270-6474

Bushell, Trevor J. and Cunningham, Margaret R. and McIntosh, Kathryn A. and Moudio, Serge and Plevin, Robin (2016) Protease-activated receptor 2 : are common functions in glial and immune cells linked to inflammation-related CNS disorders? Current Drug Targets, 17 (16). pp. 1861-1870. ISSN 1873-5592

Huesa, Carmen and Ortiz, Ana C and Dunning, Lynette and McGavin, Laura and Bennett, Louise and McIntosh, Kathryn and Crilly, Anne and Kurowska-Stolarska, Mariola and Plevin, Robin and van ,t Hof, Rob J and Rowan, Andrew D and McInnes, Iain B and Goodyear, Carl S and Lockhart, John C and Ferrell, William R (2015) Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology. Annals of the Rheumatic Diseases. ISSN 0003-4967

Martin, Tamara P. and Lawan, Ahmed and Robinson, Emma and Grieve, David J. and Plevin, Robin and Paul, Andrew and Currie, Susan (2014) Adult cardiac fibroblast proliferation is modulated by calcium/calmodulin-dependent protein kinase II in normal and hypertrophied hearts. Pflugers Archiv - European Journal of Physiology, 466 (2). 319–330. ISSN 0031-6768

Woods, Stuart and Schroeder, Juliane and McGachy, Helen A and Plevin, Robin and Roberts, Craig W and Alexander, James (2013) MAP kinase phosphatase-2 plays a key role in the control of infection with Toxoplasma gondii by modulating iNOS and arginase-1 activities in mice. PLOS Pathogens, 9 (8). e1003535.

Schroeder, Juliane and McGachy, H Adrienne and Woods, Stuart and Plevin, Robin and Alexander, James (2013) T cell hypo-responsiveness against Leishmania major in MAP kinase phosphatase (MKP) 2 deficient C57BL/6 mice does not alter the healer disease phenotype. PLOS Neglected Tropical Diseases, 7 (2). e2064.

Plevin, Robin (2012) Immunomodulatory role of proteinase-activated receptor-2. Annals of the Rheumatic Diseases, 71 (9). pp. 1559-66. ISSN 0003-4967

MacKenzie, Lewis and McCall, Pamela and Hatziieremia, Sophia and Catlow, Jamie and Adams, Claire and McArdle, Peter and Seywright, Morag and Tanahill, Claire and Paul, Andrew and Underwood, Mark and Mackay, Simon and Plevin, Robin and Edwards, Joanne (2012) Nuclear factor κB predicts poor outcome in patients with hormone-naive prostate cancer with high nuclear androgen receptor. Human pathology, 43 (9). pp. 1491-500. ISSN 1532-8392

Schroeder, J. and Ross, K. and Alexander, J. and Lawrence, C. E. and Plevin, R. (2012) Protective role of MAP kinase phosphatase 2 (MKP-2) in a model of collagen antibody induced arthritis. Immunology, 137 (1 spec). p. 585. ISSN 0019-2805

Cunningham, Margaret R. and McIntosh, Kathryn A. and Pediani, John D. and Robben, Joris and Cooke, Alexandra E. and Nilsson, Mary and Gould, Gwyn W. and Mundell, Stuart and Milligan, Graeme and Plevin, Robin (2012) Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4). Journal of Biological Chemistry, 287 (20). pp. 16656-16669. ISSN 1083-351X

Patkar, Shalmali Satish and Tate, Rothwelle and Modo, M. and Plevin, Robin and Carswell, Hilary (2012) Conditionally immortalised neural stem cells promote functional recovery and brain plasticity after transient focal cerebral ischaemia in mice. Stem Cell Research, 8 (1). 14–25.

Lawan, A. and Torrance, E. and Al-Harthi, S. and Shweash, M. and Alnasser, S. and Neamatallah, T. and Schroeder, J. and Plevin, R. (2012) MKP-2 : out of the DUSP-bin and back into the limelight. Biochemical Society Transactions, 40. pp. 235-239. ISSN 0300-5127

Shweash, Muhannad and Adrienne McGachy, H and Schroeder, Juliane and Neamatallah, Thikryat and Bryant, Clare E and Millington, Owain and Mottram, Jeremy C and Alexander, James and Plevin, Robin (2011) Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression. Molecular Immunology, 48 (15-16). pp. 1800-1808.

Lawan, Ahmed and Al-Harthi, Sameer and Cadalbert, Laurence and McCluskey, Anthony G. and Shweash, Muhannad and Grassia, Gianluca and Grant, Anne and Boyd, Marie and Currie, Susan and Plevin, Robin (2011) Deletion of the dual specific phosphatase-4 (DUSP-4) gene reveals an essential non-redundant role for MAP kinase phosphatase-2 (MKP-2) in proliferation and cell survival. Journal of Biological Chemistry, 286 (15). pp. 12933-12943. ISSN 1083-351X

Ferrell, William R. and Kelso, Elizabeth B. and Lockhart, John C. and Burns, Elizabeth and Plevin, Robin and McInnes, Iain B. (2011) Protease-activated receptor-2 (PAR-2) in the pathogenesis of osteoarthritis. Rheumatology, 50 (Supple). p. 90. ISSN 1462-0324

Gamble, Carly and McIntosh, Kathryn and Scott, Rebecca and Ho, Ka Ho and Plevin, Robin and Paul, Andrew (2011) Inhibitory kappa B kinases as targets for pharmacological regulation. British Journal of Pharmacology, 165 (4). 802–819. ISSN 1476-5381

Lutz, Eve M. and Monaghan, Thomas K. and Pou, Chantevy and Plevin, Robin and MacKenzie, Christopher J. (2010) LIF-mediated maintenance of PACAP-induced neurite outgrowths in human SH-SY5Y neuroblastoma cells require PI3K but not STAT or ERK signaling pathways. Journal of Molecular Neuroscience, 42 (3). p. 297. ISSN 0895-8696

Al-Mutairi, M.S. and Cadalbert, L.C. and McGachy, H.A. and Shweash, M.S. and Schroeder, J. and Kurnik, M. and Sloss, C.M. and Bryant, C.E. and Alexander, James and Plevin, R.J. (2010) MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana. PLOS Pathogens, 6 (11). e1001192. ISSN 1553-7366

Milner, Jennifer M and Patel, Amit and Davidson, Rose K and Swingler, Tracey E and Desilets, Antoine and Young, David A and Kelso, Elizabeth B and Donell, Simon T and Cawston, Tim E and Clark, Ian M and Ferrell, William R and Plevin, Robin and Lockhart, John C and Leduc, Richard and Rowan, Andrew D (2010) Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. Arthritis and Rheumatism, 62 (7). pp. 1955-1966.

McIntosh, K. and Cunningham, M.R. and Cadalbert, L. and Lochart, J. and Boyd, G. and Ferrell, W.R. and Plevin, R.J. (2010) Proteinase-activated receptor-2 mediated inhibition of TNFα-stimulated JNK activation — A novel paradigm for Gq/11 linked GPCRs. Cellular Signalling, 22 (2). pp. 265-273. ISSN 1873-3913

Al-Mutairi, Mashael and Al-Harthi, Sameer and Cadalbert, Laurence and Plevin, Robin (2010) Over-expression of MAP kinase phosphatase-2 enhances adhesion molecule expression and protects against apoptosis in human endothelial cells. British Journal of Pharmacology, 161 (4). pp. 782-798. ISSN 1476-5381

Ferrell, W.R. and Kelso, E.B. and Lockhart, J.C. and Plevin, R.J. and McInnes, I.B. (2010) Protease-activated receptor-2 : a novel pathogenic pathway in a murine model of osteoarthritis. Annals of the Rheumatic Diseases, 69 (11). pp. 2051-2054. ISSN 0003-4967

Goh, F.G. and Ng, P.Y. and Reilly, M. and Kanke, T. and Plevin, R. (2009) Dual effect of the novel peptide antagonist K-14585 on Proteinase-Activated Receptor-2 (PAR2)-mediated signalling. British Journal of Pharmacology, 158 (7). pp. 1695-1704. ISSN 1476-5381

Patkar, S. and Tate, R. and Modo, M. and Plevin, R.J. and Carswell, H.V.O. (2009) Characterisation of neural stem cells for oestrogen in vitro: potential for improving stem cell based therapy for stroke. Journal of Cerebral Blood Flow and Metabolism, 29. S554-S555.

Kanke, T. and Kabeya, M. and Kubo, S. and Kondo, S. and Yasuoka, K. and Tagashira, J. and Ishiwata, H. and Saka, M. and Furuyama, T. and Nishiyama, T. and Doi, T. and Hattori, Y. and Kawabata, A. and Cunningham, M.R. and Plevin, R.J. (2009) Novel antagonists for proteinase-activated receptor 2 : Inhibition of cellular and vascular responses in vitro and in vivo. British Journal of Pharmacology, 158 (1). pp. 361-371. ISSN 1476-5381

Dunning, L. and Lockhart, J.C. and Ferrell, W.R. and Plevin, R.J. and Gracie, J.A. and McInnes, I.B. and Boyd, G.W. (2009) Inhibition of murine chronic arthritis by a monoclonal antibody against protease-activated receptor-2. Rheumatology, 48 (Supple). i38-i38. ISSN 1462-0324

Cadalbert, C. and Sloss, C.M. and Cunningham, M.M. and Al-Muteiri, M. and McIntire, A. and Shipley, J. and Plevin, R. (2009) Differential regulation of MAP kinase activation by a novel splice variant of human MAP kinase phosphatase-2. Cellular Signalling, 22 (3). pp. 357-365. ISSN 1873-3913

Cunningham, M.R. and Pediani, J.D. and Milligan, G. and Plevin, R.J. (2008) TNF alpha regulation of proteinase activated receptor-2 and -4 heterodimerisation. Fundamental and Clinical Pharmacology, 22. p. 18. ISSN 0767-3981

Goh, F.G. and Sloss, C.M. and Cunningham, M.R. and Nilsson, M. and Cadalbert, Laurence and Plevin, R.J. (2008) G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 nf kappa b serine 536 phosphorylation in human keratinocytes. Cellular Signalling, 20 (7). pp. 1267-1274. ISSN 1873-3913

Ferrell, W.R. and Lockhart, J.C. and Plevin, R.J. (2008) Protease-activated receptor-2 (PAR-2): a potential new target in arthritis. Drugs of the Future, 33 (3). pp. 241-248. ISSN 0377-8282

Monaghan, T.K. and Pou, C. and MacKenzie, C.J. and Plevin, R. and Lutz, E. M. (2008) Neurotrophic actions of PACAP and LIF on human neuroblastoma SH-SY5Y cells. Journal of Molecular Neuroscience, 36 (1-3). pp. 45-56. ISSN 0895-8696

Monaghan, T.K. and MacKenzie, C.J. and Plevin, R.J. and Lutz, E. (2008) PACAP-38 induces neuronal differentiation of human SH-SY5Y neuroblastoma cells via cAMP-mediated activation of ERK and p38 MAP kinases. Journal of Neurochemistry, 104 (1). pp. 74-88. ISSN 0022-3042

McIntosh, Kathryn A and Plevin, Robin and Ferrell, William R and Lockhart, John C (2007) The therapeutic potential of proteinase-activated receptors in arthritis. Current Opinion in Pharmacology, 7 (3). pp. 334-338. ISSN 1471-4892

Ritchie, E. and Saka, M. and MacKenzie, C. and Drummond, R.M. and Wheeler-Jones, C. and Kanke, T. and Plevin, R.J. (2007) Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase ß in human endothelial cells. British Journal of Pharmacology, 150. pp. 1044-1054. ISSN 1476-5381

MacKenzie, C. and Ritchie, E. and Paul, A. and Plevin, R.J. (2007) IKKalpha and IKKbeta function in TNFalpha-stimulated adhesion molecule expression in human aortic smooth muscle cells. Cellular Signalling, 19. pp. 75-80. ISSN 1873-3913

Ferro, V.A. and Habeeb, F. and Stables, Graham and Bradbury, F. and nong, S. and Cameron, P. and Plevin, R.J. (2007) The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells. Methods, 42 (4). pp. 388-393. ISSN 1046-2023

Bushell, T. and Plevin, R.J. and Cobb, S. and Irving, A.J. (2006) Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes. Neuropharmacology, 50 (6). pp. 714-725. ISSN 0028-3908

Hatziieremia, S. and Gray, A. and Ferro, V.A. and Paul, A. and Plevin, R.J. (2006) The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and nFkappaB signalling pathways in monocytes/macrophages. British Journal of Pharmacology, 149. pp. 188-198. ISSN 1476-5381

Cameron, P. and McGachy, H.A. and Anderson, M. and Paul, A. and Coombs, G.H. and Mottram, J.C. and Alexander, J. and Plevin, R.J. (2004) Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway. Journal of Immunology, 173 (5). pp. 3297-3304. ISSN 0022-1767

Seatter, Michael J and Drummond, Robert and Kanke, Toru and Macfarlane, Scott R and Hollenberg, Morley D and Plevin, Robin (2004) The role of the C-terminal tail in protease-activated receptor-2-mediated Ca2+ signalling, proline-rich tyrosine kinase-2 activation, and mitogen-activated protein kinase activity. Cellular Signalling, 16 (1). pp. 21-29. ISSN 1873-3913

Kazerani, H. and Plevin, R.J. and Kawagoe, J. and Kanke, T. and Furman, B.L. (2004) Lack of effect of proteinase-activated receptor 2 (PAR2) deletion on the pathophysiological changes produced by lipopolysaccharide in the mouse:comparison with dexamethasone. Journal of Pharmacy and Pharmacology, 56 (8). pp. 1015-20. ISSN 0022-3573

Ferrell, William R. and Lockhart, John C. and Kelso, Elizabeth B. and Dunning, Lynette and Plevin, Robin and Meek, Stephen E. and Smith, Andrew J.H. and Hunter, Gary D. and McLean, John S. and McGarry, Frances and Ramage, Robert and Jiang, Lu and Kanke, Toru and Kawagoe, Junichi (2003) Essential role for proteinase-activated receptor-2 in arthritis. Journal of Clinical Investigation, 111 (1). pp. 35-41. ISSN 0021-9738

Cameron, P. and Smith, S.J. and Giembycz, M.A. and Rotondo, D. and Plevin, R.J. (2003) Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release. British Journal of Pharmacology, 140 (7). pp. 1320-1330. ISSN 1476-5381

Takizawa, T. and Wada, Y. and Matsumoto, J. and Tamiya, M. and Smith, A.J.H. and Plevin, R.J. and Kanke, T. and Saino, Y. (2002) Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear. Japanese Journal of Pharmacology, 88 (1). pp. 77-84. ISSN 0021-5198

Cameron, P. and Bingham, D. and Paul, A. and Pavelka, M. and Cameron, S. and Rotondo, D. and Plevin, R.J. (2002) Essential role for verotoxin in sustained stress-activated protein kinase and nuclear factor kappa b signaling, stimulated by escherichia coli o157:H7 in vero cells. Infection and Immunity, 70 (10). pp. 5370-5380. ISSN 0019-9567

McDonald, M.C. and Mota-Filipe, H. and Paul, A. and Cuzzocrea, S. and Abdelrahman, M. and Harwood, S. and Plevin, R.J. and Chatterjee, P.K. and Yaqoob, M.M. and Thiemermann, C. (2001) Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock. FASEB Journal, 15 (1). pp. 171-186. ISSN 0892-6638

Torrie, L.J. and MacKenzie, C. and Paul, A. and Plevin, R.J. (2001) Hydrogen peroxide-mediated inhibition of lipopolysaccharide-stimulated inhibitory kappa b kinase activity in rat aortic smooth muscle cells. British Journal of Pharmacology, 134 (2). pp. 393-401. ISSN 1476-5381

Robinson, C. and Sloss, C.M. and Plevin, R.J. (2001) Inactivation of jNK ACtivity by mitogen-activated protein kinase phosphatase-2 in Eahy926 endothelial cells is dependent upon agonist-specific jNK translocation to the nucleus. Cellular Signalling, 13 (1). pp. 29-41. ISSN 1873-3913

Kanke, T. and MacFarlane, S.R. and Seatter, M.J. and Davenport, E.L. and Paul, A. and McKenzie, R.C. and Plevin, R.J. (2001) Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa b kinases in NCTC 2544 keratinocytes. Journal of Biological Chemistry, 276 (34). pp. 31657-31666. ISSN 1083-351X

Belham, C M and Tate, R J and Scott, P H and Pemberton, A D and Miller, H R and Wadsworth, R M and Gould, G W and Plevin, R (1996) Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases. Biochemical journal, 320 ( Pt . pp. 939-46. ISSN 0264-6021

Plevin, R and MacNulty, E E and Palmer, S and Wakelam, M J (1991) Differences in the regulation of endothelin-1- and lysophosphatidic-acid-stimulated Ins(1,4,5)P3 formation in rat-1 fibroblasts. Biochemical journal, 280 (3). pp. 609-615. ISSN 0264-6021

Plevin, R and Cook, S J and Palmer, S and Wakelam, M J (1991) Multiple sources of sn-1,2-diacylglycerol in platelet-derived-growth-factor-stimulated Swiss 3T3 fibroblasts. Evidence for activation of phosphoinositidase C and phosphatidylcholine-specific phospholipase D. Biochemical Journal, 279 (2). pp. 559-565. ISSN 0264-6021

Plevin, R and MacNulty, E E and Palmer, S and Wakelam, M J (1991) Differences in the coupling of ET-1 and LPA receptors in Ins(1,4,5)P3 formation in Rat-1 fibroblasts. Biochemical Society Transactions, 19 (2). 100S. ISSN 0300-5127

Palmer, S and Plevin, R and Wakelam, M J (1991) Homologous desensitization of bombesin-stimulated Ins(1,4,5)P3 production in Swiss 3T3 fibroblasts. Biochemical Society Transactions, 19 (2). 101S. ISSN 0300-5127

Wakelam, M.J. and Cook, S.J. and Currie, Susan and Palmer, S. and Plevin, Robin (1991) Regulation of the hydrolysis of phosphatidylcholine in Swiss 3T3 cells. Biochemical Society Transactions, 19 (2). pp. 321-324. ISSN 0300-5127

Plevin, R and Palmer, S and Gardner, S D and Wakelam, M J (1990) Regulation of bombesin-stimulated inositol 1,4,5-trisphosphate generation in Swiss 3T3 fibroblasts by a guanine-nucleotide-binding protein. Biochemical journal, 268 (3). pp. 605-610. ISSN 0264-6021

Cook, S J and Plevin, R and Palmer, S and Wakelam, M J (1990) Bombesin and platelet-derived growth factor stimulate phosphatidylcholine breakdown by a common mechanism. Biochemical Society Transactions, 18 (3). pp. 484-485. ISSN 0300-5127

Cook, S J and Palmer, S and Plevin, R and Wakelam, M J (1990) Mass measurement of inositol 1,4,5-trisphosphate and sn-1,2-diacylglycerol in bombesin-stimulated Swiss 3T3 mouse fibroblasts. Biochemical journal, 265 (2). pp. 617-620. ISSN 0264-6021

Book Section

Cunningham, Margaret Rose and Plevin, Robin; Offermanns, Stefan and Rosenthal, Walter, eds. (2008) Proteinase-activated receptors (PARs). In: Encyclopedia of Molecular Pharmacology. Springer, Berlin, pp. 1019-1023. ISBN 9783540389163

Cook, S and Palmer, Susan and Plevin, Robin and Wakelam, M J; Ross, Elliott M. and Wirtz, Karel W.A., eds. (1990) Multiple sources of sn-1,2-diacylglycerol in mitogen-stimulated Swiss 3T3 cells : evidence for activation of phosphoinositidase C and PtdChophospholipase D. In: Biological Signal Transduction. Springer Berlin Heidelberg, pp. 421-434. ISBN 978-3-642-75138-7

Conference or Workshop Item

Kelso, E.B. and Dunning, L. and Lockhart, J.C. and Ferrell, W.R. and Plevin, R. and Sommerhoff, C.P. (2005) Tryptase as a PAR-2 activator in joint inflammation. In: 25th European Workshop for Rheumatology Research, 2005-02-24 - 2005-02-27.

Review

Milner, J. M. and Patel, A. and Davidson, R. K. and Swingler, T. E. and Desilets, A. and Young, D. A. and Kelso, E. B. and Donell, S. T. and Cawston, T. E. and Clark, I. M. and Ferrell, W. R. and Plevin, R. and Lockhart, J. C. and Leduc, R. and Rowan, A. D. (2010) Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. [Review]

Milner, J. M. and Patel, A. and Davidson, R. K. and Swingler, T. E. and Desilets, A. and Young, D. A. and Kelso, E. B. and Donell, S. T. and Cawston, T. E. and Clarke, I. M. and Ferrell, W. R. and Plevin, R. and Lockhart, J. C. and Leduc, R. and Rowan, A. D. (2010) Matriptase is a novel initiator of cartilage matrix resorption in osteoarthritis. [Review]