The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells

Ferro, V.A. and Habeeb, F. and Stables, Graham and Bradbury, F. and nong, S. and Cameron, P. and Plevin, R.J. (2007) The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells. Methods, 42 (4). pp. 388-393. ISSN 1046-2023

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Abstract

The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.

Author(s):Ferro, V.A., Habeeb, F., Stables, Graham, Bradbury, F., nong, S., Cameron, P. and Plevin, R.J.
Item type:Article
ID code:10387
Keywords:aloe vera , anti-inflammatory, inflammation, pro-inflammatory cytokines, Pharmacy and materia medica, Therapeutics. Pharmacology, Biochemistry, Genetics and Molecular Biology(all), Molecular Biology
Subjects:Medicine > Pharmacy and materia medica
Medicine > Therapeutics. Pharmacology
Department:Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Faculty of Science
Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences > Physiology and Pharmacology
Depositing user: Strathprints Administrator
Date deposited:28 Nov 2011 15:13
Last modified:05 Jun 2019 05:29
URI:https://strathprints.strath.ac.uk/id/eprint/10387
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