The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells

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Ferro, V.A. and Habeeb, F. and Stables, Graham and Bradbury, F. and nong, S. and Cameron, P. and Plevin, R.J. (2007) The inner gel component of aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells. Methods, 42 (4). pp. 388-393. ISSN 1046-2023 (https://doi.org/10.1016/j.ymeth.2007.03.005)

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Abstract

The present study was carried out to examine the anti-inflammatory activity of the inner leaf gel component of Aloe barbadensis Miller. A simple in vitro assay was designed to determine the effect of the inner gel on bacterial-induced pro-inflammatory cytokine production, namely TNF-α and IL-1β, from peripheral blood leukocytes stimulated with Shigella flexneri or LPS. This report describes the suppression of both cytokines with a freeze-dried inner gel powder and a commercial health drink from the same source. Comparison was made with a human monocytic cell-line (THP-1 cells) and a similar trend in responses was demonstrated.

ORCID iDs

Ferro, V.A. ORCID logoORCID: https://orcid.org/0000-0003-1967-3603, Habeeb, F., Stables, Graham, Bradbury, F., nong, S., Cameron, P. and Plevin, R.J. ORCID logoORCID: https://orcid.org/0000-0002-7849-1220;
CORE (COnnecting REpositories)