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World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

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Number of items: 27.

Cooper, Ian R. and McCarroll, Andrew J. and McGarry, David and Kirkham, James and Pichowicz, Mark and Walker, Rolf and Warrilow, Catherine and Salisbury, Anne-Marie and Savage, Victoria J. and Moyo, Emmanuel and Forward, Henry and Cheung, Jonathan and Metzger, Richard and Gault, Zoe and Nelson, Gary and Hughes, Diarmaid and Cao, Sha and Maclean, John and Charrier, Cédric and Craighead, Mark and Best, Stuart and Stokes, Neil R. and Ratcliffe, Andrew J. (2016) Discovery and structure-activity relationships of a novel isothiazolone class of bacterial type II topoisomerase inhibitors. Bioorganic and Medicinal Chemistry Letters, 26 (17). pp. 4179-83. ISSN 0960-894X

Scott, Fraser J. and Khalaf, Abedawn I. and Duffy, Sandra and Avery, Vicky M. and Suckling, Colin J. (2016) Selective anti-malarial minor groove binders. Bioorganic and Medicinal Chemistry Letters, 26. pp. 3326-3329. ISSN 0960-894X

Scott, Fraser and Khalaf, Abedawn and Suckling, Colin and Carter, Katharine and Grant, Mary and Henderson, Catherine and Westrop, Gareth and Watson, David (2016) An evaluation of minor groove binders as anti-lung cancer therapeutics. Bioorganic and Medicinal Chemistry Letters. ISSN 0960-894X (In Press)

Wilkinson, Craig and McPhillie, Martin J and Zhou, Ying and Woods, Stuart and Afanador, Gustavo A and Rawson, Shaun and Khaliq, Farzana and Prigge, Sean T and Roberts, Craig W and Rice, David W and McLeod, Rima and Fishwick, Colin W and Muench, Stephen P (2014) The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target. Bioorganic and Medicinal Chemistry Letters, 24 (3). pp. 911-916. ISSN 0960-894X

Cheng, Gang and Muench, Stephen P and Zhou, Ying and Afanador, Gustavo A and Mui, Ernest J and Fomovska, Alina and Lai, Bo Shiun and Prigge, Sean T and Woods, Stuart and Roberts, Craig W and Hickman, Mark R and Lee, Patty J and Leed, Susan E and Auschwitz, Jennifer M and Rice, David W and McLeod, Rima (2013) Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase. Bioorganic and Medicinal Chemistry Letters, 23 (7). pp. 2035-2043. ISSN 0960-894X

Cowley, Phillip M and Baker, James and Buchanan, Kirsteen I and Carlyle, Ian and Clark, John K and Clarkson, Thomas R and Deehan, Maureen and Edwards, Darren and Kiyoi, Yasuko and Martin, Iain and Osbourn, Dawn and Walker, Glenn and Ward, Nick and Wishart, Grant (2011) Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB1 antagonists. Bioorganic and Medicinal Chemistry Letters, 21 (7). pp. 2034-2039. ISSN 0960-894X

Kiyoi, Takao and Adam, Julia M and Clark, John K and Davies, Keneth and Easson, Anna-Marie and Edwards, Darren and Feilden, Helen and Fields, Ruth and Francis, Stuart and Jeremiah, Fiona and McArthur, Duncan and Morrison, Angus J and Prosser, Alan and Ratcliffe, Paul D and Schulz, Jurgen and Wishart, Grant and Baker, James and Campbell, Robert and Cottney, Jean E and Deehan, Maureen and Epemolu, Ola and Evans, Louise (2011) Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists. Bioorganic and Medicinal Chemistry Letters, 21 (6). pp. 1748-1753. ISSN 0960-894X

Jamieson, Craig and Maclean, John K.F. and Brown, Christopher I and Campbell, Robert A and Gillen, Kevin J. and Gillespie, Jonathan and Kazemier, Bert and Kiczun, Michael and LAMONT, YVONNE and Lyons, Amanda J. and Moir, Elizabeth M. and Morrow, John A. and Pantling, John and Rankovic, Zoran and Smith, Lynn (2011) Structure based evolution of a novel series of positive modulators of the AMPA receptor. Bioorganic and Medicinal Chemistry Letters, 21 (2). pp. 805-811. ISSN 0960-894X

Jamieson, Craig and Campbell, Robert A. and Cumming, Iain A. and Gillen, Kevin J. and Gillespie, Jonathan and Kazemier, Bert and Kiczun, Michael and Lamont, Yvonne and Lyons, Amanda J. and Maclean, John K.F. and Martin, Frederic and Moir, Elizabeth M. and Morrow, John A. and Pantling, John and Rankovic, Zoran and Smith, Lynn (2010) A novel series of positive modulators of the AMPA receptor : structure-based lead optimization. Bioorganic and Medicinal Chemistry Letters, 20 (20). pp. 6072-6075. ISSN 0960-894X

Jamieson, Craig and Basten, Stephanie and Campbell, Robert A. and Cumming, Iain A. and Gillen, Kevin J. and Gillespie, Jonathan and Kazemier, Bert and Kiczun, Michael and Lamont, Yvonne and Lyons, Amanda J. and Maclean, John K.F. and Moir, Elizabeth M. and Morrow, John A. and Papakosta, Marianthi and Rankovic, Zoran and Smith, Lynn (2010) A novel series of positive modulators of the AMPA receptor : discovery and structure based hit-to-lead studies. Bioorganic and Medicinal Chemistry Letters, 20 (19). pp. 5753-5756. ISSN 0960-894X

Letourneau, Jeffrey J and Jokiel, Patrick and Olson, John and Riviello, Christopher M and Ho, Koc-Kan and McAleer, Lihong and Yang, Jingchun and Swanson, Robert N and Baker, James and Cowley, Phillip and Edwards, Darren and Ward, Nick and Ohlmeyer, Michael H J and Webb, Maria L (2010) Identification and hit-to-lead optimization of a novel class of CB1 antagonists. Bioorganic and Medicinal Chemistry Letters, 20 (18). pp. 5449-5453. ISSN 0960-894X

Kiyoi, Takao and York, Mark and Francis, Stuart and Edwards, Darren and Walker, Glenn and Houghton, Andrea K and Cottney, Jean E and Baker, James and Adam, Julia M (2010) Design, synthesis, and structure-activity relationship study of conformationally constrained analogs of indole-3-carboxamides as novel CB1 cannabinoid receptor agonists. Bioorganic and Medicinal Chemistry Letters, 20 (16). pp. 4918-4921. ISSN 0960-894X

Rankovic, Zoran and Cai, Jiaqiang and Fradera, Xavier and Dempster, Maureen and Mistry, Ashvin and Long, Clive and Hamilton, Emma and King, Angela and Boucharens, Sylviane and Jamieson, Craig and Gillespie, Jonathan and Cumming, Iain and Uitdehaag, Joost and van Zeeland, Mario. (2010) Dioxo-triazines as a novel series of cathepsin K inhibitors. Bioorganic and Medicinal Chemistry Letters, 20 (5). pp. 1488-1490. ISSN 0960-894X

Berg, M. and van der Veken, P. and Joossens, J. and Muthusamy, V. and Breugelmans, M. and Moss, C.X. and Rudolf, J. and Coombs, G.H. (2010) Design and evaluation of Trypanosoma brucei metacaspase inhibitors. Bioorganic and Medicinal Chemistry Letters, 20 (6). pp. 2001-2006. ISSN 0960-894X

Mayer, G. and Lohberger, A. and Butzen, S. and Pofahl, M. and Blind, M. and Heckel, A. (2009) From selection to caged aptamers: identification of light-dependent ssdna aptamers targeting cytohesin. Bioorganic and Medicinal Chemistry Letters, 19 (23). pp. 6561-6564.

Ingram, A.M. and Moore, B.D. and Graham, D. (2009) Simultaneous detection of alkaline phosphatase and beta-galactosidase activity using SERRS. Bioorganic and Medicinal Chemistry Letters, 19 (6). pp. 1569-1571. ISSN 0960-894X

Suckling, Colin J. and Gibson, C.L. and Huggan, Judith K. and Morthala, Raghavendar R. and Clarke, Brendan and Kununthur, Suma and Wadsworth, Roger M. and Daff, Simon and Papale, Davide (2008) 6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases. Bioorganic and Medicinal Chemistry Letters, 18 (5). pp. 1563-1566. ISSN 0960-894X

EI-Subbagh, H.I. and El-Kashef, H.A. and Kadi, A.A. and Abdel-Aziz, A.A.M. and Hassan, G.S. and Tettey, J.N.A. and Lehmann, J. (2008) New ultra-short acting hypnotic: Synthesis, biological evaluation, and metabolic profile of ethyl 8-oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a][1,3]diazepin-3-carboxylate (HIE-124). Bioorganic and Medicinal Chemistry Letters, 18 (1). pp. 72-77. ISSN 0960-894X

Suckling, C.J. and Murphy, J.A. and Khalaf, A.I. and Zhou, S. and Lizos, D.E. and Nguyen Van Nhien, A. and Yasumatsu, H. and McVie, A. and Young, L.C. and McCraw, C. and Waterman, P.G. and Morris, B.J. and Pratt, J.A. and Harvey, A. (2007) M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds. Bioorganic and Medicinal Chemistry Letters, 17 (9). pp. 2649-2655. ISSN 0960-894X

Clark, Rachael L. and Carter, Katharine C. and Mullen, Alexander B. and Coxon, Geoffrey D. and Owusu-Dapaah, George and McFarlane, Emma and Dao Duong Thi, M. and Grant, M.H. and Tettey, J.N.A. and Mackay, Simon P. (2007) Identification of the benzodiazepines as a new class of antileishmanial agent. Bioorganic and Medicinal Chemistry Letters, 17 (3). pp. 624-627. ISSN 0960-894X

Bhowruth, V. and Brown, A.K. and Reynolds, R.C. and Coxon, G.D. and Mackay, S.P. and Minnikin, D.E. and Besra, G.S. (2006) Symmetrical and unsymmetrical analogues of isoxyl; active agents against mycobacterium tuberculosis. Bioorganic and Medicinal Chemistry Letters, 16 (18). pp. 4743-4747. ISSN 0960-894X

Clark, R.L. and Johnston, B.F. and Suckling, C.J. and Mackay, S.P. (2006) A modelling study of a non-concerted hydrolytic cycloaddition reaction by the catalytic antibody H11. Bioorganic and Medicinal Chemistry Letters, 14. pp. 2674-2683. ISSN 0960-894X

Suckling, C.J. and Hampshire, Andrew J. and Khairallah, Hannah and Khalaf, A.I. and Ebrahimabadi, Abdolrasoul H. and Waigh, R.D. and Brown, Tom and Fox, Keith R. (2006) DNA sequence recognition by an imidazole-containing isopropyl thiazole polyamide (thiazotropsin b). Bioorganic and Medicinal Chemistry Letters, 16 (13). pp. 3469-3474.

Anthony, N.G. and Fox, K.R. and Johnston, B.F. and Khalaf, A.I. and Mackay, S.P. and McGroarty, I.S. and Parkinson, J.A. and Skellern, G.G. and Suckling, C.J. and Waigh, R.D. (2004) DNA binding of a short lexitropsin. Bioorganic and Medicinal Chemistry Letters, 14 (5). pp. 1353-1356. ISSN 0960-894X

Cairns, D. and Michalitsi, E. and Jenkins, T.C. and Mackay, S.P. (2002) Molecular modelling and cytotoxicity of substituted anthraquinonesas inhibitors of human telomerase. Bioorganic and Medicinal Chemistry Letters, 10. pp. 803-807. ISSN 0960-894X

Parks, Derek J. and Tomkinson, Nicholas C. O. and Villeneuve, Manon S. and Blanchard, Steven G. and Willson, Timothy M. (1998) Differential activity of rosiglitazone enantiomers at PPARγ. Bioorganic and Medicinal Chemistry Letters, 8 (24). pp. 3657-3658. ISSN 0960-894X

Tomkinson, Nicholas C. O. and Sefler, Andrea M. and Plunket, Kelli D. and Blanchard, Steven G. and Parks, Derek J. and Willson, Timothy M. (1997) Solid-phase synthesis of hybrid thiazolidinedione-fatty acid PPARγ ligands. Bioorganic and Medicinal Chemistry Letters, 7 (19). pp. 2491-2496. ISSN 0960-894X

This list was generated on Thu Aug 17 21:48:03 2017 BST.