Browse by Author or creator

Article

Foylan, Shannan and Schniete, Jana Katharina and Kölln, Lisa Sophie and Dempster, John and Hansen, Carsten Gram and Shaw, Michael and Bushell, Trevor John and McConnell, Gail (2023) Mesoscale standing wave imaging. Journal of Microscopy, 295 (1). pp. 33-41. ISSN 0022-2720

Tinning, Peter W. and Schniete, Jana K. and Scrimgeour, Ross and Kölln, Lisa S. and Rooney, Liam M. and Bushell, Trevor J. and McConnell, Gail (2023) A simple image processing pipeline to sharpen topology maps in multi-wavelength interference microscopy. Optics Letters, 48 (5). pp. 1092-1095. ISSN 0146-9592

Megarity, D. and Vroman, R. and Kriek, M. and Downey, P. and Bushell, T. J. and Zagnoni, M. (2022) A modular microfluidic platform to enable complex and customisable in vitro models for neuroscience. Lab on a Chip, 22 (10). pp. 1989-2000. ISSN 1473-0197

Barbour, Mark and Wood, Rachel and Harte, Tanith and Bushell, Trevor J. and Jiang, Hui-Rong (2022) Anti-CD52 antibody treatment in murine experimental autoimmune encephalomyelitis induces dynamic and differential modulation of innate immune cells in peripheral immune and central nervous systems. Immunology, 165 (3). pp. 312-327. ISSN 0019-2805

AlDawsari, Asma and Bushell, Trevor J. and Abutheraa, Nouf and Sakata, Shuzo and Al Hussain, Sarah and Kurdi, Amanj (2022) Use of sedative-hypnotic medications and risk of dementia : a systematic review and meta-analysis. British Journal of Clinical Pharmacology, 88 (4). pp. 1567-1589. ISSN 0306-5251

Moudio, Serge and Willis, Ashleigh and Pytka, Karolina and Abulkassim, Roua and Brett, Ros R. and Webster, Jack F. and Wozny, Christian and Barbour, Mark and Jiang, Hui-Rong and Watson, David G. and van Kralingen, Josie C. and Mackenzie, Scott M. and Daniels, Michael and McColl, Barry W. and Sossick, Sandra and Nuthall, Hugh N. and Bushell, Trevor J. (2022) Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines. Psychopharmacology, 239 (1). pp. 229-242. ISSN 0033-3158

Hridi, Shehla U and Barbour, Mark and Wilson, Chelsey and Franssen, Aimee JPM and Harte, Tanith and Bushell, Trevor J and Jiang, Hui-Rong (2021) Increased levels of IL-16 in the central nervous system during neuroinflammation are associated with infiltrating immune cells and resident glial cells. Biology, 10 (6). 472. ISSN 2079-7737

Schniete, Jana K. and Tinning, Peter W. and Scrimgeour, Ross C. and Robb, Gillian and Kölln, Lisa S. and Wesencraft, Katrina and Paul, Nikki R. and Bushell, Trevor J. and McConnell, Gail (2021) An evaluation of multi-excitation-wavelength standing-wave fluorescence microscopy (TartanSW) to improve sampling density in studies of the cell membrane and cytoskeleton. Scientific Reports, 11. 2903. ISSN 2045-2322

McIntosh, Kathryn A. and Cunningham, Margaret R. and Bushell, Trevor and Plevin, Robin (2020) The development of proteinase-activated receptor-2 modulators and the challenges involved. Biochemical Society Transactions, 48 (6). pp. 2525-2537. BST20200191. ISSN 0300-5127

Pytka, Karolina and Dawson, Neil and Tossell, Kyoko and Ungless, Mark A. and Plevin, Robin and Brett, Ros R. and Bushell, Trevor J. (2020) Mitogen‐activated protein kinase phosphatase‐2 deletion modifies ventral tegmental area function and connectivity and alters reward processing. European Journal of Neuroscience, 52 (2). pp. 2838-2852. ISSN 0953-816X

Hridi, Shehla U. and Franssen, Aimée J.P.M. and Jiang, Hui-Rong and Bushell, Trevor J. (2019) Interleukin-16 inhibits sodium channel function and GluA1 phosphorylation via CD4- and CD9-independent mechanisms to reduce hippocampal neuronal excitability and synaptic activity. Molecular and Cellular Neuroscience, 95. pp. 71-78. ISSN 1044-7431

Schniete, Jan and Franssen, Aimee and Dempster, John and Bushell, Trevor J and Amos, William Bradshaw and McConnell, Gail (2018) Fast optical sectioning for widefield fluorescence mesoscopy with the mesolens based on HiLo microscopy. Scientific Reports, 8. 16259. ISSN 2045-2322

Ritchie, Louise and Tate, Rothwelle and Chamberlain, Luke H. and Robertson, Graham and Zagnoni, Michele and Sposito, Teresa and Wray, Selina and Wright, John A. and Bryant, Clare E. and Gay, Nicholas J. and Bushell, Trevor J. (2018) Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons. Neuropharmacology, 135. pp. 1-10. ISSN 0028-3908

Tinning, P. W. and Franssen, A. J. P. M. and Hridi, S. U. and Bushell, T. J. and McConnell, G. (2018) A 340/380 nm light emitting diode illuminator for Fura-2 AM ratiometric Ca2+ imaging of live cells with better than 5 nM precision. Journal of Microscopy, 269 (3). pp. 212-220. ISSN 0022-2720

Barbour, Mark and Wood, Rachel and Hridi, Shehla U and Wilson, Chelsey and McKay, Grant and Bushell, Trevor J and Jiang, Hui-Rong (2018) The therapeutic effect of anti-CD52 treatment in murine experimental autoimmune encephalomyelitis is associated with altered IL-33 and ST2 expression levels. Journal of Neuroimmunology. pp. 1-33. ISSN 0165-5728

Salaun, Christine and Ritchie, Louise and Greaves, Jennifer and Bushell, Trevor J. and Chamberlain, Luke H. (2017) The C-terminal domain of zDHHC2 contains distinct sorting signals that regulate intracellular localisation in neurons and neuroendocrine cells. Molecular and Cellular Neuroscience, 85. ISSN 1044-7431

MacKerron, Christopher and Robertson, Graham and Zagnoni, Michele and Bushell, Trevor (2017) A microfluidic platform for the characterisation of CNS active compounds. Scientific Reports. ISSN 2045-2322

Cain, Stuart M and Garcia, Esperanza and Waheed, Zeina and Jones, Karen L and Bushell, Trevor J and Snutch, Terrance P (2017) GABAB receptors suppress burst-firing in reticular thalamic neurons. Channels. pp. 1-13. ISSN 1933-6969

Hridi, Shehla Unaiza and McCann, Lee and McConnell, Gail and Bushell, Trevor J and Jiang, Hui-Rong (2017) Increased expression of IL-16 in the brain of experimental autoimmune encephalomyelitis. Brain and Neuroscience Advances. P-M113. ISSN 2398-2128

Abulkassim, Roua and Brett, Ros and MacKenzie, Scott M. and Bushell, Trevor J. (2016) Proteinase-activated receptor 2 is involved in the behavioural changes associated with sickness behaviour. Journal of Neuroimmunology, 295-296. pp. 139-147. ISSN 0165-5728

Currie, Susan and Martin, Tamara Patricia and Salleh, Hanif and McCluskey, Claire and Bushell, Trevor John (2016) Inositol trisphosphate receptor contribution to ventricular cardiac fibroblast function in healthy and hypertrophied mouse hearts. FASEB Journal, 30 (1 Supp). 1178.2. ISSN 0892-6638

Cunningham, Margaret and McIntosh, Kathryn and Bushell, Trevor and Sloan, Graeme and Plevin, Robin (2016) Proteinase-activated receptors (PARs) as targets for antiplatelet therapy. Biochemical Society Transactions, 44 (2). pp. 606-612. ISSN 0300-5127

Abdul Rahman, Nor Zaihana Binti and Greenwood, Sam M. and Brett, Ros R. and Tossell, Kyoko and Ungless, Mark A. and Plevin, Robin and Bushell, Trevor J. (2016) Mitogen-activated protein kinase phosphatase-2 deletion impairs synaptic plasticity and hippocampal-dependent memory. Journal of Neuroscience, 36 (8). pp. 2348-2354. ISSN 0270-6474

Amor, Rumelo and McDonald, Alison and Trägårdh, Johanna and Robb, Gillian and Wilson, Louise and Abdul Rahman, Nor Zaihana and Dempster, John and Amos, William Bradshaw and Bushell, Trevor J. and McConnell, Gail (2016) Widefield two-photon excitation without scanning : live cell microscopy with high time resolution and low photo-bleaching. PLOS One, 11 (1). 0147115. ISSN 1932-6203

Bushell, Trevor J. and Cunningham, Margaret R. and McIntosh, Kathryn A. and Moudio, Serge and Plevin, Robin (2016) Protease-activated receptor 2 : are common functions in glial and immune cells linked to inflammation-related CNS disorders? Current Drug Targets, 17 (16). pp. 1861-1870. ISSN 1873-5592

Sposito, Teresa and Preza, Elisavet and Mahoney, Colin J. and Setó-Salvia, Núria and Ryan, Natalie S. and Morris, Huw R. and Arber, Charles and Devine, Michael J. and Houlden, Henry and Warner, Thomas T. and Bushell, Trevor J. and Zagnoni, Michele and Kunath, Tilo and Livesey, Frederick J. and Fox, Nick C. and Rossor, Martin N. and Hardy, John and Wray, Selina (2015) Developmental regulation of tau splicing is disrupted in stem cell derived neurons from frontotemporal dementia patients with the 10+16 splice-site mutation in MAPT. Human Molecular Genetics, 24 (18). pp. 5260-5269. ISSN 0964-6906

Mohd Salleh, M and McCluskey, C and Bushell, T and Currie, S (2014) Calcium/calmodulin dependent protein kinase II δ modulates intracellular CA2+ release and cell proliferation in adult cardiac fibroblasts. Heart, 100 (S4). ISSN 1468-201X

Robertson, Graham and Bushell, Trevor J. and Zagnoni, Michele (2014) Chemically induced synaptic activity between mixed primary hippocampal co-cultures in a microfluidic system. Integrative Biology, 6 (6). pp. 636-644. ISSN 1757-9694

Shrestha, Rajeev and Shakya Shrestha, S. and Millington, O. and Brewer, J. and Bushell, T. (2014) Immune responses in neurodegenerative diseases. Kathmandu University Medical Journal, 12 (45). pp. 67-76. ISSN 1812-2027

Shrestha Maleku, Rajeev and Millington, Owain and Brewer, James and Dev, Kumlesh and Bushell, Trevor (2014) Lymphocyte-mediated neuroprotection in in vitro models of excitotoxicity involves astrocytic activation and the inhibition of MAP kinase signalling pathways. Neuropharmacology, 76 (A). pp. 184-193. ISSN 0028-3908

Abulkassim, R. and Bushell, T. J. and Brett, R. R. (2011) Deletion of proteinase activated receptor 2 has limited effects on anxiety behaviours and spares reference and working memory. Journal of Psychopharmacology, 25 (8 Supp). A51-A51. ISSN 1461-7285

Gan, J. and Greenwood, S.M. and Cobb, S.R. and Bushell, T.J. (2011) Indirect modulation of neuronal excitability and synaptic transmission in the hippocampus by activation of proteinase-activated receptor-2. British Journal of Pharmacology, 163 (5). pp. 984-994. ISSN 1476-5381

Fumagalli, Stefano and Coles, Jonathan A and Ejlerskov, Patrick and Ortolano, Fabrizio and Bushell, Trevor J and Brewer, James M and De Simoni, Maria-Grazia and Dever, Gary and Garside, Paul and Maffia, Pasquale and Carswell, Hilary V (2011) In vivo real-time multiphoton imaging of T lymphocytes in the mouse brain after experimental stroke. Stroke, 42 (5). pp. 1429-1436. ISSN 0039-2499

Ledgerwood, Craig and Greenwood, Sam M. and Brett, R.R. and Pratt, J.A. and Bushell, T. (2011) Cannabidiol inhibits synaptic transmission in rat hippocampal cultures and slices via multiple receptor pathways. British Journal of Pharmacology, 162 (1). pp. 286-294. ISSN 1476-5381

Greenwood, Sam M. and Bushell, T.J. (2010) Astrocytic activation and an inhibition of MAP kinases are required for proteinase-activated receptor-2-mediated protection from neurotoxicity. Journal of Neurochemistry, 113 (6). pp. 1471-1480. ISSN 0022-3042

Shakya-Shrestha, S. and Parmar, M. and Kennedy, Charles and Bushell, T. (2010) Two-pore potassium ion channels are inhibited by both Gq/11- and Gi-coupled P2Y receptors. Molecular and Cellular Neuroscience, 43 (4). pp. 363-369. ISSN 1044-7431

Ortolano, F. and Maffia, Pasquale and Dever, G. and Rodolico, G. and Millington, O.R. and De Simoni, M.G. and Brewer, J.M. and Bushell, T. and Garside, P. and Carswell, H.V.O. (2010) Advances in imaging of new targets for pharmacological intervention in stroke : real time tracking of T cells in the ischaemic brain. British Journal of Pharmacology, 159 (4). pp. 808-811. ISSN 1476-5381

Pytka, Karolina and Librowski, Tadeusz and Filipek, Barbara and Paul, Andrew and Bushell, Trevor (2010) Does receptor activation initiate the NF kappa B pathway in hippocampal neurones? Pharmacological Reports, 62 (supple). p. 59. ISSN 1734-1140

Ortolano, F. and Maffia, Pasquale and Dever, G. and Hutchison, S. and Benson, R. and Millington, O.R. and De Simoni, M.G. and Bushell, T. and Garside, P. and Carswell, H.V. and Brewer, J.M. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31 (3). pp. 147-150. ISSN 0141-9838

Cain, Stuart M. and Meadows, Helen J. and Dunlop, John and Bushell, T. (2008) mGlu4 potentiation of K2P2.1 is dependant on C-terminal dephosphorylation. Molecular and Cellular Neuroscience, 37 (1). pp. 32-39. ISSN 1044-7431

Bushell, T. (2007) The emergence of proteinase-activated receptor-2 as a novel target for the treatment of inflammation-related CNS disorders. Journal of Physiology, 581 (1). pp. 7-16. ISSN 0022-3751

Bushell, T. and Plevin, R.J. and Cobb, S. and Irving, A.J. (2006) Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes. Neuropharmacology, 50 (6). pp. 714-725. ISSN 0028-3908

Bushell, Trevor J. and Sansig, Gilles and Collett, Valerie J. and van der Putten, Herman and Collingridge, Graham L. (2002) Altered short-term synaptic plasticity in mice lacking the metabotropic glutamate receptor mGlu7. ScientificWorld Journal, 2. pp. 730-737. ISSN 1537-744X

Downie, D.L. and Vicente-Agullo, F. and Campos-Caro, A. and Bushell, T. and Lieb, W.R. and Franks, N.P. (2002) Determinants of the anesthetic sensitivity of neuronal nicotinic acetylcholine receptors. Journal of Biological Chemistry, 277. pp. 10367-10373. ISSN 1083-351X

Bushell, T. and Endoh, T. and Simen, A.A. and Ren, D. and Bindokas, V.P. and Miller, R.J. (2002) Molecular components of tolerance to opiates in single hippocampal neurons. Molecular Pharmacology, 61 (1). pp. 55-64. ISSN 0026-895X

Marks, J.D. and Pan, C.Y. and Bushell, T. and Cromie, W. and Lee, R.C. (2001) Amphiphilic, tri-block copolymers provide potent, membrane-targeted neuroprotection. FASEB Journal, 15. pp. 1107-1109. ISSN 0892-6638

Sansig, G. and Bushell, T. and Clarke, V.R. and Rozov, A. and Burnashev, N. and Portet, C. and Gasparini, F. and Schmutz, M. and Klebs, K. and Shigemoto, R. and Flor, P.J. and Kuhn, R. and Knoepfel, T. and Schroeder, M. and Hampson, D.R. and Collett, V.J. and Zhang, C. and Duvoisin, R.M. and Collingridge, G.L. and van der Putten, Herman (2001) Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7. Journal of Neuroscience, 21 (22). pp. 8734-8745. ISSN 0270-6474

Book Section

Robertson, G. and Sposito, T. and Wray, S. and Hardy, J. and Bushell, T.J. and Zagnoni, M.; (2016) Dementia on a chip : monitoring synaptic dysfunction of patient derived human neurons. In: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016). Chemical and Biological Microsystems Society, IRL, pp. 379-380. ISBN 9781510834163

MacKerron, C. and Robertson, G. and Bushell, T.J. and Zagnoni, M.; (2016) Perfusion based microfluidic system for pharmacological profiling of neuronal networks. In: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016). Chemical and Biological Microsystems Society, IRL, pp. 445-446. ISBN 9781510834163

Torrance, Emma and Robertson, Graham and Wray, Selina and Hardy, John and Bushell, Trevor and Zagnoni, Michele; (2014) A microfluidics platform for human tau mutation neurons. In: MicroTAS 2014. CBM Society, USA, pp. 898-890. ISBN 9780979806476

Conference or Workshop Item

Tinning, Peter William and Franssen, Aimee and Hridi, Shehla Unaiza and Bushell, Trevor and McConnell, Gail (2017) A 340/380 nm light emitting diode illuminator for Fura-2 AM ratiometric Ca2+ imaging of live cells with better than 5 nM precision. In: Microscience Microscopy Congress 2017, 2017-07-03 - 2017-07-06.

Wilson, Chelsey and Bushell, Trevor and Jiang, Hui-Rong (2017) Expression of IL-22 and IL-22R1 subunit in the central nervous system of experimental autoimmune encephalomyelitis mice. In: BSI Edinburgh Immunology Conference. Edinburgh, UK, 2017-06-15 - 2017-06-15.

Tinning, Peter William and Franssen, Aimee and Hridi, Shehla Unaiza and Bushell, Trevor and McConnell, Gail (2017) A 340/380 nm light emitting diode illuminator for Fura-2 AM ratiometric Ca2+ imaging of live cells with better than 5 nM precision. In: Photonex, 2017-06-14 - 2017-06-14.

Hridi, Shehla Unaiza and McCann, Lee and McConnell, Gail and Bushell, Trevor and Jiang, Hui-Rong (2016) Expression of IL-16 in central nervous system during the development of experimental autoimmune encephalomyelitis. In: BSI/NVVI congress 2016, 2016-12-06 - 2016-12-09, ACC.

Wilson, Chelsey and Bushell, Trevor and Jiang, Hui-Rong (2016) Expression of IL-22 and IL-22R1 subunit in the central nervous system of experimental autoimmune encephalomyelitis mice. In: BSI/NVVI congress 2016, 2016-12-06 - 2016-12-09, ACC.

MacKerron, Christopher and Robertson, Graham and Bushell, Trevor and Zagnoni, Michele (2016) A novel microfluidic drug testing platform for studying communication between independent neural networks. In: 10th FENS (Federation of European Neuroscience Societies) Forum of Neuroscience 2016, 2016-07-02 - 2016-07-06.

Brett, R.R. and Pratt, J.A. and Bushell, T. and Ledgerwood, Craig (2008) Exposure of cultured hippocampal neurones to cannabidiol does not induce cell death but inhibits synaptic activity. In: 18th Annual Symposium of the International Cannabinoid Research Society, 2008-06-25 - 2008-06-29. (Unpublished)