A microfluidics platform for human tau mutation neurons

Torrance, Emma and Robertson, Graham and Wray, Selina and Hardy, John and Bushell, Trevor and Zagnoni, Michele; (2014) A microfluidics platform for human tau mutation neurons. In: MicroTAS 2014. CBM Society, USA, pp. 898-890. ISBN 9780979806476 (http://www.rsc.org/images/loc/2014/PDFs/Papers/294...)

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This paper reports a microfluidic approach for assessing network formation in human induced pluripotent stem cell (iPSC)-derived neurons. For the first time, we show the ability of iPSC-derived neurons to form functional synaptically driven networks within a controlled microfluidic environment, thus providing an in vitro stem cell based model for studying dementia.


Torrance, Emma, Robertson, Graham ORCID logoORCID: https://orcid.org/0000-0002-3841-874X, Wray, Selina, Hardy, John, Bushell, Trevor ORCID logoORCID: https://orcid.org/0000-0003-4145-9670 and Zagnoni, Michele ORCID logoORCID: https://orcid.org/0000-0003-3198-9491;