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Discover open research at Strathprints as part of International Open Access Week!

23-29 October 2017 is International Open Access Week. The Strathprints institutional repository is a digital archive of Open Access research outputs, all produced by University of Strathclyde researchers.

Explore recent world leading Open Access research content this Open Access Week from across Strathclyde's many research active faculties: Engineering, Science, Humanities, Arts & Social Sciences and Strathclyde Business School.

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A microfluidics platform for human tau mutation neurons

Torrance, Emma and Robertson, Graham and Wray, Selina and Hardy, John and Bushell, Trevor and Zagnoni, Michele (2014) A microfluidics platform for human tau mutation neurons. In: MicroTAS 2014. CBM Society, San Diego, CA., pp. 898-890. ISBN 9780979806476

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Abstract

This paper reports a microfluidic approach for assessing network formation in human induced pluripotent stem cell (iPSC)-derived neurons. For the first time, we show the ability of iPSC-derived neurons to form functional synaptically driven networks within a controlled microfluidic environment, thus providing an in vitro stem cell based model for studying dementia.