A novel microfluidic drug testing platform for studying communication between independent neural networks

MacKerron, Christopher and Robertson, Graham and Bushell, Trevor and Zagnoni, Michele (2016) A novel microfluidic drug testing platform for studying communication between independent neural networks. In: 10th FENS (Federation of European Neuroscience Societies) Forum of Neuroscience 2016, 2016-07-02 - 2016-07-06.

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    Abstract

    Many in-vitro systems used during pre-clinical trials fail to recreate the biological complexity of the in-vivo neural microenvironment.Taking advantage of recent advances in microfluidic technology, we seek to develop a perfusion based drug discovery platform that is capable of high-throughput pharmacological profiling. This in turn will allow us to better understand how drugs influence the communication between functionally connected neural networks.

    ORCID iDs

    MacKerron, Christopher ORCID logoORCID: https://orcid.org/0000-0002-8741-5078, Robertson, Graham ORCID logoORCID: https://orcid.org/0000-0002-3841-874X, Bushell, Trevor ORCID logoORCID: https://orcid.org/0000-0003-4145-9670 and Zagnoni, Michele ORCID logoORCID: https://orcid.org/0000-0003-3198-9491;