Browse by Author or creator
Article
Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Boyd, Marie and Breen, David and Edwards, Joanne and Gamble, Carly and Gray, Alexander I. and Harvey, Alan L. and Hatziieremia, Sophia and Ho, Ka Ho and Huggan, Judith K. and Lang, Stuart and Llona-Minguez, Sabin and Luo, Jia Lin and McIntosh, Kathryn and Paul, Andrew and Plevin, Robin J. and Robertson, Murray N. and Scott, Rebecca and Suckling, Colin J. and Sutcliffe, Oliver Brook and Young, Louise C. and MacKay, Simon P. (2017) Inhibitory Kappa B kinase α (IKKα) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers. Journal of Medicinal Chemistry, 60 (16). pp. 7043-7066. ISSN 0022-2623
Khreit, Osama IG and Grant, Helen M and Henderson, Catherine and Watson, David G and Sutcliffe, Oliver B (2016) Identification of novel metabolic pathways of sitagliptin (STG) by LC/MS and LC/MS2 after incubations with rat hepatcoytes. Drug Metabolism and Disposition, 7 (4). 1000220. ISSN 1521-009X
Connor, Lauren E. and Delori, Amit and Hutchison, Ian B. and Nic Daeid, Niamh and Sutcliffe, Oliver B. and Oswald, Iain D. H. (2015) The Ecstasy and the agony; compression studies of 3,4-methylenedioxymethamphetamine (MDMA). Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials, 71 (1). pp. 3-9. ISSN 2052-5192
Delori, Amit and Maclure, Pauline and Bhardwaj, Rajni M. and Johnston, Andrea and Florence, Alastair J. and Sutcliffe, Oliver B. and Oswald, Iain D. H. (2014) Drug solid solutions - a method for tuning phase transformations. CrystEngComm, 16 (26). pp. 5827-5831. ISSN 1466-8033
Satthaphut, Natsiri and Sutcliffe, Oliver B. and Oswald, Iain D. H. (2014) Putting the squeeze on mephedrone hydrogen sulfate. Zeitschrift fur Kristallografie, 229 (2). pp. 101-111. ISSN 0044-2968
Nic Daeid, Niamh and Savage, Kathleen A. and Ramsay, Donna and Holland, Ciara and Sutcliffe, Oliver B. (2014) Development of gas chromatography-mass spectrometry (GC-MS) and other rapid screening methods for the analysis of 16 'legal high' cathinone derivatives. Science and Justice, 54 (1). pp. 22-31. ISSN 1355-0306
Khreit, Osama Idris Gibreel and Grant, Mary and Zhang, Tong and Henderson, Catherine and Watson, David and Sutcliffe, Oliver Brook (2013) Elucidation of the phase I and phase II metabolic pathways of (+/-)-4'-nethylmethcathinone (4-MMC) and (+/-)-4'-(trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS2. Journal of Pharmaceutical and Biomedical Analysis, 72. pp. 177-185. ISSN 1873-264X
Bawazeer, Saud and Sutcliffe, Oliver B and Euerby, Melvin R and Bawazeer, Sami and Watson, David G (2012) A comparison of the chromatographic properties of silica gel and silicon hydride modified silica gels. Journal of Chromatography A, 1263. pp. 61-67.
Abualhasan, Murad N. and Good, James A. D. and Wittayanarakul, Kitiyaporn and Anthony, Nahoum G. and Berretta, Giacomo and Rath, Oliver and Kozielski, Frank and Sutcliffe, Oliver B. and Mackay, Simon P. (2012) Doing the methylene shuffle - further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine. European Journal of Medicinal Chemistry, 54. pp. 483-498. ISSN 0223-5234
Khreit, Osama I. G. and Irving, Craig and Schmidt, Elke and Parkinson, John A. and Daeid, Niamh Nic and Sutcliffe, Oliver B. (2012) Synthesis, full chemical characterisation and development of validated methods for the quantification of the components found in the evolved “legal high” NRG-2. Journal of Pharmaceutical and Biomedical Analysis, 61. pp. 122-135. ISSN 1873-264X
Wang, F. and Good, J. A. D. and Rath, O. and Kaan, H. Y. K. and Sutcliffe, O. B. and Mackay, S. P. and Kozielski, F. (2012) Triphenylbutanamines : kinesin spindle protein inhibitors with in vivo antitumor activity. Journal of Medicinal Chemistry, 55 (4). pp. 1511-1525. ISSN 0022-2623
Baiget, Jessica and Llona-Minguez, Sabin and Lang, Stuart and MacKay, Simon P. and Suckling, Colin J. and Sutcliffe, Oliver B. (2011) Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate : concise synthesis of alangiobussinine. Beilstein Journal of Organic Chemistry, 7. pp. 1407-1411. ISSN 1860-5397
Santali, Eman Y. and Cadogan, Anna-Karina and Daeid, Niamh Nic and Savage, Kathleen A. and Sutcliffe, Oliver B. (2011) Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4′-methylmethcathinone (mephedrone) : a new "legal high". Journal of Pharmaceutical and Biomedical Analysis, 56 (2). pp. 246-255. ISSN 1873-264X
Kirkpatrick, Gordon J and Plumb, Jane A and Sutcliffe, Oliver B and Flint, David J and Wheate, Nial J (2011) Evaluation of anionic half generation 3.5-6.5 poly(amidoamine) dendrimers as delivery vehicles for the active component of the anticancer drug cisplatin. Journal of Inorganic Biochemistry, 105 (9). pp. 1115-1122.
Sutcliffe, O. B. and Daeid, N. N. and Khreit, O. I. G. (2011) Tackling the forensic analytical challenges associated with the global increase in seizures of cathinone-derived "legal highs". Abstracts of papers - American Chemical Society, 242. 188-ANYL.
Abualhasan, M. and Sutcliffe, O. B. and Kozielski, F. and Mackay, S. P. (2010) Design and synthesis of novel EG5 inhibitors. Journal of Pharmacy and Pharmacology, 62 (10). p. 1367. ISSN 0022-3573
Naredo-Gonzalez, G. and Jansen, M. A. and Merrifield, G. D. and Sutcliffe, O. B. and Hansen, M. K. and Andrew, R. and Walker, B. R. (2010) Non-invasive in-vivo monitoring of 11 beta-HSD1 activity using F-19-magnetic resonance spectroscopy. Endocrine Reviews, 31 (3 - Su). ISSN 0163-769X
Clark, Rachel and Johnston, Blair and Mackay, Simon and Breslin, Catherine and Robertson, Murray and Sutcliffe, Oliver Brook and Dufton, Mark and Harvey, Alan (2010) The drug discovery portal : a computational platform for identifying drug leads from academia. Current Pharmaceutical Design, 16 (15). pp. 1697-1702. ISSN 1381-6128
Wheate, N.J. and Patel, Nilesh and Sutcliffe, O.B. (2010) Microwave synthesis of curcurbit[n]urils. Future Medicinal Chemistry, 2 (2). pp. 231-236. ISSN 1756-8919
Clark, R.L. and Johnston, B.F. and Mackay, S.P. and Breslin, C.J. and Robertson, Murray and Sutcliffe, O.B. and Dufton, M.J. and Harvey, A.L. (2010) The drug discovery portal : a computational platform for identifying drug leads from academia. Current Pharmaceutical Design, 16 (15). pp. 1697-1702. ISSN 1381-6128
Foster, Paul A. and Chander, S.K. and Newman, Simon P. and Woo, L.W. Lawrence and Sutcliffe, O.B. and Bubert, C. and Zhou, Dujin and Chen, Shiuan and Potter, B.V.L. and Reed, M.J. and Purohit, A. (2008) A new therapeutic strategy against hormone-dependent breast cancer: the preclinical development of a dual aromatase and sulfatase inhibitor. Clinical Cancer Research, 14. pp. 6469-6477. ISSN 1557-3265
Bubert, C. and Woo, L.W.L. and Sutcliffe, O.B. and Mahon, M.F. and Chander, S.K. and Purohit, A. and Reed, M.J. and Potter, B.V.L. (2008) Synthesis of aromatase inhibitors and dual aromatase-sulfatase inhibitors by linking an arylsulfamate motif to 4-(4H-1,2,4-triazol-4-ylamino)benzonitrile: SAR, crystal structures, in vitro and in vivo activities. ChemMedChem, 3 (11). pp. 1708-1730. ISSN 1860-7179
Woo, L.W.L. and Bubert, C. and Sutcliffe, O.B. and Smith, A. and Chander, S.K. and Mahon, M.F. and Purohit, A. and Reed, M.J. and Potter, B.V.L. (2007) Dual aromatase-steroid sulfatase inhibitors. Journal of Medicinal Chemistry, 50 (15). pp. 3540-3560. ISSN 0022-2623
Lloyd, M D and Thiyagarajan, N and Ho, Y T and Woo, L W L and Sutcliffe, O B and Purohit, A and Reed, M J and Acharya, K R and Potter, B V L (2005) First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors. BMC Biochemistry, 44 (18). pp. 6858-6866. ISSN 1471-2091
Sutcliffe, O B and Bryce, M R (2003) Planar chiral 2-ferrocenyloxazolines and 1,1 '-bis(oxazolinyl)ferrocenes-syntheses and applications in asymmetric catalysis. Tetrahedron: Asymmetry, 14 (16). pp. 2297-2325. ISSN 0957-4166
Woo, L.W.L. and Sutcliffe, O.B. and Bubert, C. and Grasso, A. and Chander, S.K. and Purohit, A. and Reed, M.J. and Potter, B.V.L. (2003) First dual aromatase-steroid sulfatase inhibitors. Journal of Medicinal Chemistry, 46 (15). pp. 3193-3196. ISSN 0022-2623
Sutcliffe, O.B. and Bryce, M.R. and Batsanov, A.S. (2002) Synthesis of novel chiral bis(ferrocenyl) ligands and their use as voltammetric metal cation sensors. Journal of Organometallic Chemistry, 656 (1-2). pp. 211-216. ISSN 0022-328X
Sutcliffe, O B and Chesney, A and Bryce, M R (2001) Voltammetric metal cation sensors based on ferrocene derivatives with oxazoline and imine substituents. Journal of Organometallic Chemistry, 637 (Specia). pp. 134-138. ISSN 0022-328X
Sutcliffe, O.B. and Storr, R.C. and Gilchrist, T.L. and Rafferty, P. (2001) Azafulvenium methides: new extended dipolar systems. Journal of the Chemical Society, Perkin Transactions 1, 2001 (15). pp. 1759-1806. ISSN 1472-7781
Sutcliffe, O B and Storr, R C and Gilchrist, T L and Rafferty, P (2000) Cycloadditions to pyrrolo[1,2-c]thiazoles and pyrazolo[1,5-c]thiazoles. Tetrahedron, 56 (51). pp. 10011-10021. ISSN 0040-4020
Sutcliffe, O B and Storr, R C and Gilchrist, T L and Rafferty, P and Crew, A P A (2000) Azafulvenium methides : new extended dipolar systems. Chemical Communications (London) (8). pp. 675-676. ISSN 0009-241X
Conference or Workshop Item
Kirkpatrick, G.J. and Sutcliffe, O.B. and Flint, D.J. and Wheate, N.J. (2009) PAMAM dendrimers as drug delivery vehicles for platinum anticancer drugs. In: Gordon Research Conference: Metals in Medicine, 2009-06-28 - 2009-07-02.