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Article

Alniss, Hasan Y H and Salvia, Marie-Virginie and Sadikov, Mykhailo and Golovchenko, Igor and Anthony, Nahoum Guillaume Hsuan and Khalaf, Abedawn and MacKay, Simon and Suckling, Colin and Parkinson, John (2014) Minor groove recognition of DNA by thiazotropsin analogues. Chembiochem. ISSN 1439-4227 (In Press)

Salvia, Marie-Virginie and Addison, Fiona and Alniss, Hasan Y H and Buurma, Niklaas J and Khalaf, Abedawn and MacKay, Simon and Anthony, Nahoum G and Suckling, Colin and Evstigneev, Maxim P and Santiago, Adrian Hernandez and Waigh, Roger and Parkinson, John (2013) Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor groove. Biophysical Chemistry, 179. pp. 1-11. ISSN 0301-4622

Talapatra, Sandeep K. and Anthony, Nahoum Guillaume Hsuan and MacKay, Simon and Kozielski, Frank (2013) The mitotic kinesin Eg5 overcomes inhibition to the phase I/II clinical candidate SB743921 by an allosteric resistance mechanism. Journal of Medicinal Chemistry, 56 (16). pp. 6317-6329. ISSN 0022-2623

Abualhasan, Murad N. and Good, James A. D. and Wittayanarakul, Kitiyaporn and Anthony, Nahoum G. and Berretta, Giacomo and Rath, Oliver and Kozielski, Frank and Sutcliffe, Oliver B. and Mackay, Simon P. (2012) Doing the methylene shuffle - further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine. European Journal of Medicinal Chemistry, 54. pp. 483-498. ISSN 0223-5234

Alniss, Hasan Y and Anthony, Nahoum Guillaume Husan and Khalaf, Abedawn and Mackay, Simon and Suckling, Colin and Waigh, Roger and Wheate, Nial and Parkinson, John (2012) Rationalising sequence selection by ligand assemblies in the DNA minor groove : the case for thiazotropsin A. Chemical Science, 3 (3). pp. 711-722. ISSN 2041-6520

Khalaf, Abedawn I and Anthony, Nahoum and Breen, David and Donoghue, Gavin and Mackay, Simon P and Scott, Fraser J and Suckling, Colin J (2011) Amide isosteres in structure-activity studies of antibacterial minor groove binders. European Journal of Medicinal Chemistry, 46 (11). pp. 5343-5355.

Wheate, N.J. and Vora, V. and Anthony, N.G. and McInnes, F.J. (2010) Host-guest complexes of the antituberculosis drugs pyrazinamide and isoniazid with cucurbit[7]uril. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 68 (3-4). pp. 359-367. ISSN 0923-0750

Wittayanarakul, Kitiyaporn and Anthony, N.G. and Treesuwan, Witcha and Hannongbua, Supa and Alniss, Hasan and Khalaf, A.I. and Suckling, C.J. and Parkinson, J.A. and Mackay, Simon P. and , Royal Golden Jubilee Ph.D. Program (Funder) and , Thailand Research Fund (Funder) and , W.T. and EPSRC (Funder) and , Scottish Funding Council (Funder) (2010) Ranking ligand affinity for the DNA minor groove by experiment and simulation. Medicinal Chemistry Letters, 1 (8). pp. 376-680. ISSN 1948-5875

McInnes, F.J. and Anthony, N.G. and Kennedy, Alan R. and Wheate, Nial J. (2010) Solid state stabilisation of the orally delivered drugs atenolol, glibenclamide, memantine and paracetamol through their complexation with cucurbit[7]uril. Organic and Biomolecular Chemistry, 8 (4). pp. 765-773. ISSN 1477-0520

Treesuwan, Witcha and Wittayanarakul, Kitiyaporn and Anthony, Nahoum G. and Huchet, Guillaume and Alniss, Hasan and Hannongbua, Supa and Khalaf, Abedawn I. and Suckling, Colin J. and Parkinson, John A. and Mackay, Simon P. (2009) A detailed binding free energy study of 2 : 1 ligand–DNA complex formation by experiment and simulation. Physical Chemistry Chemical Physics, 11 (45). pp. 10682-10693. ISSN 1463-9076

Al-Balas, Qosay and Anthony, Nahoum G. and Al-Jaidi, Bilal and Alnimr, Amani and Abbott, Grainne and Brown, Alistair K. and Taylor, Rebecca C. and Besra, Gurdyal S. and McHugh, Timothy D. and Gillespie, Stephen H. and Johnston, Blair F. and Mackay, Simon P. and Coxon, Geoffrey D. (2009) Identification of 2-Aminothiazole-4-Carboxylate derivatives active against mycobacterium tuberculosis H37Rv and the beta-ketoacyl-ACP synthase mtFabH. PLoS One, 4 (5). e5617. ISSN 1932-6203

Anthony, N.G. and Breen, D. and Donoghue, G. and Khalaf, A.I. and Mackay, S.P. and Parkinson, J.A. and Suckling, C.J. (2009) A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity. Organic and Biomolecular Chemistry, 7 (9). pp. 1843-1850. ISSN 1477-0520

Parkinson, J.A. and Khalaf, A.I. and Anthony, N.G. and Mackay, S.P. and Suckling, C.J. and Waigh, R.D. (2009) Comparison of DNA complex formation behaviour for two closely related lexitropsin analogues. Helvetica Chimica Acta, 92 (5). pp. 795-822. ISSN 0018-019X

Nunthanavanit, Patcharawee and Anthony, N.G. and Johnston, B.F. and Mackay, S.P. and Ungwitayatorn, Jiraporn (2008) 3D-QSAR studies on chromone derivatives as HIV-1 protease inhibitors: application of molecular field analysis. Archiv der Pharmazie, 341 (6). pp. 357-364. ISSN 0365-6233

Anthony, Nahoum Guillaume Hsuan and Breen, D. and Clarke, Joanna and Donoghue, Gavin and Drummond, Allan J. and Ellis, Elizabeth and Gemmell, Curtis G. and Helesbeux, Jean-Jacques and Hunter, Iain. S. and Khalaf, Abedawn and MacKay, Simon and Parkinson, J.A. and Suckling, C.J. and Waigh, R.D. (2007) Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups. Journal of Medicinal Chemistry, 50 (24). pp. 6116-6125. ISSN 0022-2623

Clark, R.L. and Deane, F.M. and Anthony, N.G. and Johnston, B.F. and McCarthy, F.O. and Mackay, S.P. (2007) Exploring DNA topoisomerase I inhibition by the benzo[c]phenanthridines fagaronine and ethoxidine using steered molecular dynamics. Bioorganic and Medicinal Chemistry, 15 (14). pp. 4741-4752.

Anthony, N.G. and Huchet, G. and Johnston, B.F. and Parkinson, B.F. and Suckling, C.J. and Waigh, R.D. and Mackay, S.P. (2005) In Silico Footprinting of Ligands Binding to the Minor Groove of DNA. Journal of Chemical Information and Modeling, 45 (6). pp. 1896-1907. ISSN 1549-9596

Khalaf, A.I. and Ebrahimabadi, A.H. and Drummond, A.J. and Anthony, N.G. and Mackay, S.P. and Suckling, C.J. and Waigh, R.D. (2004) Synthesis and antimicrobial activity of some netropsin analogues. Organic and Biomolecular Chemistry, 2 (21). pp. 3119-3127. ISSN 1477-0520

Anthony, N.G. and Johnston, B.F. and Khalaf, A.I. and Mackay, S.P. and Parkinson, J.A. and Suckling, C.J. and Waigh, R.D. (2004) Short Lexitropsin that Recognizes the DNA Minor Groove at 5'-ACTAGT-3': Understanding the Role of Isopropyl-thiazole. Journal of the American Chemical Society, 126 (36). pp. 11338-11349. ISSN 0002-7863

Anthony, N.G. and Johnston, B.F. and Mackay, S.P. and Suckling, C.J. and Waigh, R.D. (2004) An in silico footprinting technique to study ligand interactions in the minor groove of DNA. Drugs of the Future, 29 (Suppl. A). p. 150. ISSN 0377-8282

Anthony, N.G. and Fox, K.R. and Johnston, B.F. and Khalaf, A.I. and Mackay, S.P. and McGroarty, I.S. and Parkinson, J.A. and Skellern, G.G. and Suckling, C.J. and Waigh, R.D. (2004) DNA binding of a short lexitropsin. Bioorganic and Medicinal Chemistry Letters, 14 (5). pp. 1353-1356. ISSN 0960-894X

Proceedings Paper

Llona-Minguez, S. and Anthony, N. and Mackay, S. (2011) Design and synthesis of novel and selective IKK inhibitors. [Proceedings Paper]

This list was generated on Fri Aug 29 14:41:33 2014 BST.