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Article

Bordos, Ecaterina and Das, Gunjan and Schroeder, Sven L.M. and Florence, Alastair and Halbert, Gavin W. and Robertson, John (2025) Probing the interplay between drug saturation, processing temperature and microstructure of amorphous solid dispersions with synchrotron X-ray phase-contrast tomography. International Journal of Pharmaceutics, 669. 125018. ISSN 1873-3476

Jolliffe, Hikaru Graeme and Velazco-Roa, Maria A. and de Juan, Luis Martin and Prostredny, Martin and Mendez Torrecillas, Carlota and Reynolds, Gavin and McElhone, Deborah and Robertson, John (2025) Characterisation of a continuous blender : impact of physical properties on mass holdup behaviour. Powder Technology, 449. 120440. ISSN 0032-5910

Barrera, Maria Cecilia and Leech, Damien and Josifovic, Aleksandar and Tolouei, Anita and Alford, Gareth and Wallace, Martin J. and Bennett, Nicholas and Wildman, Ricky and Irvine, Derek J. and Croft, Anna and Özcan, Ender and Florence, Alastair J. and Johnston, Blair and Robertson, John and Brown, Cameron J. (2025) Optimisation of additively manufactured coiled flow inverters for continuous viral inactivation processes. Chemical Engineering Research and Design, 213. pp. 126-136. ISSN 0263-8762

Prostredny, Martin and Jolliffe, Hikaru Graeme and Elkes, Richard and Maqsood, Khalid and Song, Yunfei li and Reynolds, Gavin and Meir, Bernhard and Robertson, John (2024) Development and process scaling of repeat mini-blending as a complementary approach to deliver continuous direct compression. Powder Technology, 448. 120224. ISSN 0032-5910

Salehian, Mohammad and Moores, Jonathan and Goldie, Jonathan and Ibrahim, Isra and Mendez Torrecillas, Carlota and Wale, Ishwari and Abbas, Faisal and Maclean, Natalie and Robertson, John and Florence, Alastair and Markl, Daniel (2024) A hybrid system of mixture models for the prediction of particle size and shape, density, and flowability of pharmaceutical powder blends. International Journal of Pharmaceutics: X, 8. 100298. ISSN 2590-1567

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2024) An Additive Manufacturing MicroFactory : overcoming brittle material failure and improving product performance through tablet microstructure control for an immediate release dose form. Polymers, 16 (18). 2566. ISSN 2073-4360

Tait, Theo and Salehian, Mohammad and Aroniada, Magdalini and Shier, Andrew P. and Elkes, Richard and Robertson, John and Markl, Daniel (2024) Empirical model variability : developing a new global optimisation approach to populate compression and compaction mixture rules. International Journal of Pharmaceutics, 662. 124475. ISSN 1873-3476

Jolliffe, Hikaru G. and Prostredny, Martin and Mendez Torrecillas, Carlota and Bordos, Ecaterina and Tierney, Colette and Ojo, Ebenezer and Elkes, Richard and Reynolds, Gavin and Song, Yunfei Li and Meir, Bernhard and Fathollahi, Sara and Robertson, John (2024) A modified Kushner-Moore approach to characterising small-scale blender performance impact on tablet compaction. International Journal of Pharmaceutics, 659. 124232. ISSN 1873-3476

Brown, Cameron J. and McGinty, John and Islam, Muhammad T. and Rajoub, Nazer and Arjmandi-Tash, Omid and Ottoboni, Sara and Shahid, Muhid and Urwin, Stephanie J. and Lee, Ye Seol and Chong, Magdalene W. S. and Papathanasiou, Foteini and Prakash, Aruna S. and Prasad, Elke and Spence, Bronwyn and Sefcik, Jan and Robertson, John and Smith, Rachel and Litster, James D. and Price, Chris J. and Nordon, Alison and Adjiman, Claire S. and Florence, Alastair J. (2024) Integrated continuous process design for crystallisation, spherical agglomeration, and filtration of lovastatin. Journal of Pharmaceutical Innovation, 19 (2). 9. ISSN 1939-8042

Prasad, Elke and Robertson, John and Florence, Alastair J. and Halbert, Gavin W. (2023) Expanding the pharmaceutical formulation space in material extrusion 3D printing applications. Additive Manufacturing, 77. 103803. ISSN 2214-8604

Jolliffe, Hikaru G. and Ojo, Ebenezer and Mendez Torrecillas, Carlota and Houson, Ian and Elkes, Richard and Reynolds, Gavin and Kong, Angela and Meehan, Elizabeth and Becker, Felipe Amado and Piccione, Patrick M. and Verma, Sudhir and Singaraju, Aditya and Halbert, Gavin and Robertson, John (2022) Linked experimental and modelling approaches for tablet property predictions. International Journal of Pharmaceutics, 626. 122116. ISSN 1873-3476

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2022) Mefenamic acid solid dispersions : impact of formulation composition on processing parameters, product properties and performance. International Journal of Pharmaceutics, 616. 121505. ISSN 1873-3476

Prasad, Elke and Robertson, John and Halbert, Gavin (2020) Improving consistency for a Mefenamic acid immediate release formulation. Journal of Pharmaceutical Sciences. ISSN 0022-3549

Bordos, Ecaterina and Islam, Muhammad T. and Florence, Alastair J. and Halbert, Gavin W. and Robertson, John (2019) Use of terahertz-Raman spectroscopy to determine solubility of the crystalline active pharmaceutical ingredient in polymeric matrices during hot melt extrusion. Molecular Pharmaceutics, 16 (10). pp. 4361-4371. ISSN 1543-8384

Prasad, Elke and Islam, Muhammad T. and Goodwin, Daniel J. and Megarry, Andrew J. and Halbert, Gavin W. and Florence, Alastair J. and Robertson, John (2019) Development of a hot-melt extrusion (HME) process to produce drug loaded Affinisol™ 15LV filaments for Fused Filament Fabrication (FFF) 3D printing. Additive Manufacturing, 29. 100776. ISSN 2214-8604

Tahir, Furqan and Islam, Muhammad T. and Mack, John and Robertson, John and Lovett, David (2019) Process monitoring and fault detection on a hot-melt extrusion process using in-line Raman spectroscopy and a hybrid soft sensor. Computers and Chemical Engineering, 125. pp. 400-414. ISSN 0098-1354

Torrecillas, Carlota Mendez and Gorringe, Lee J. and Rajoub, Nazer and Robertson, John and Elkes, Richard G. and Lamprou, Dimitrios A. and Halbert, Gavin W. (2018) The impact of channel fill level on internal forces during continuous twin screw wet granulation. International Journal of Pharmaceutics. pp. 1-43. ISSN 1873-3476

McLaughlin, Arabella and Robertson, John and Ni, Xiong-Wei (2018) Material characterisation and parameter effects on bulk solid dissolution rate of paracetamol in a stirred tank vessel using an in situ UV-ATR probe. International Journal of Engineering Research and Science, 4 (1). pp. 10-20. ISSN 2395-6992

Halliwell, Rebecca A. and Bhardwaj, Rajni M. and Brown, Cameron and Briggs, Naomi E. B. and Dunn, Jaclyn and Robertson, John and Nordon, Alison and Florence, Alastair J. (2017) Spray drying as a reliable route to produce metastable carbamazepine form IV. Journal of Pharmaceutical Sciences, 106 (7). pp. 1874-1880. ISSN 0022-3549

Sullivan, F. M. and Farmer, Eoghan and Mair, Frances S. and Treweek, Shaun and Kendrick, Denise and Jackson, Cathy and Robertson, Chris and Briggs, Andrew and McCowan, Colin and Bedford, Laura and Young, Ben and Vedhara, Kavita and Gallant, Stephanie and Littleford, Roberta and Robertson, John and Sewell, Herb and Dorward, Alistair and Sarvesvaran, Joseph and Schembri, Stuart (2017) Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS) : study protocol for a randomized controlled trial. BMC Cancer, 17. ISSN 1471-2407

Book Section

Jolliffe, Hikaru G. and Papathanasiou, Foteini and Prasad, Elke and Halbert, Gavin and Robertson, John and Brown, Cameron J. and Florence, Alastair J.; (2019) Improving the prediction of multi-component tablet properties from pure component parameters. In: 29th European Symposium on Computer Aided Chemical Engineering. Computer Aided Chemical Engineering, 46 . Elsevier, NLD, pp. 883-888. ISBN 9780128186350

Conference or Workshop Item

Prasad, Elke and Robertson, John and Halbert, Gavin (2024) Additive manufacturing MicroFactory for amorphous solid dispersion formulations. In: CMAC Showcase 2024, 2024-09-16 - 2024-09-16, TIC.

Prasad, Elke and Hueckman, Jill and Bordos, Ecaterina and Robertson, John and Halbert, Gavin W. (2024) 3D printing MicroFactory for amorphous solid dispersion formulations. In: CMAC Summer School 2024, 2023-07-10 - 2024-07-14.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2023) The EPSRC future manufacturing research HUB : 3D printing microfactory. In: CMAC Open Days 2023, 2023-11-14 - 2023-11-16, Technology & Innovation Centre, 99 George Street.

Prasad, Elke and Bordos, Ecaterina and Langford, Vaughan and Perkins, Mark and Robertson, John and Halbert, Gavin W. (2023) Linking 3DP manufacturing with SIFT-MS volatiles organic compound analysis. In: AAPS 2023 PHARMSCI 360, 2023-10-22 - 2023-10-25, Orange County Convention Center.

Smith, Aaron and Bordos, Ecaterina and Robertson, John and Florence, Alastair (2023) The application of SIFT-MS for examining the degradation of polymers. In: CMAC Summer School, 2023-06-14 - 2023-06-16.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2023) 3D Printing MicroFactory. In: CMAC Summer School, 2023-06-12 - 2023-06-16.

Prasad, Elke and Robertson, John and Halbert, Gavin (2023) An Novel Additive Manufacturing Micro-factory: Overcoming limitations of pharmaceutical formulations. In: SIPBS Research Day, 2023-06-01 - 2023-06-01.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2022) Identifying the operating space and repeatability of a novel filament free FDM printer. In: AAPS 2022 Pharm Sci 360, 2022-10-16 - 2022-10-19, USA.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2022) Printability of pharmaceutical Fused Deposition Modeling (FDM) feedstock material : mechanical characterisation of FDM filaments and the FDM 3D printing process. In: AAPS 2022 Pharm Sci 360, 2022-10-16 - 2022-10-19, USA.

Vivattanaseth, Pattavet and Chong, Magdalene and Prasad, Elke and Halbert, Gavin and Robertson, John and McFarlan, Catriona and Nordon, Alison (2022) Application of multivariate curve resolution to in situ THz - Raman spectroscopy of amorphous solid dispersions in pharmaceutical products. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Chong, Magdalene and Brown, Cameron and Mustoe, Chantal and McGinty, John and Li, Wei and Pathan, Momina and Ottoboni, Sara and Prasad, Elke and Robertson, Murray and Mehta, Bhavik and McGowan, Mark and Siddique, Humera and Raval, Vishal and Pereira Diaz, Laura and Siddique, Mariam and Eales, William and Turner, Alice and Johnston, Blair and Robertson, John and Halbert, Gavin and Price, Chris and Benyahia, Brahim and Rielly, Chris and Sefcik, Jan and Nordon, Alison and McGlone, Thomas and Smith, Kenneth and Feilden, Helen and Houson, Ian and Florence, Alastair (2022) The CMAC MicroFactory : mefenamic acid. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Osman, Musab and Markl, Daniel and Robertson, John (2022) Enhancing virtual tablet formulation design. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Josifovic, Aleksander and Barrera, Maria and Brown, Cameron and Johnston, Blair and Robertson, John and Florence, Alastair (2022) In-line process reactor test bed & sensor development. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Jolliffe, Hikaru and Mendez Torrecillas, Carlota and Prostredny, Martin and Devlin, Michael and Bordos, Ecaterina and Markl, Daniel and Robertson, John (2022) Medicines Manufacturing Innovation Centre (MMIC) : the use of a Digital Twin. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Mendez Torrecillas, Carlota and Prostredny, Martin and Devlin, Michael and Bordos, Ecaterina and Robertson, John (2022) Process activities to develop a Digital Twin MMIC GC1 : introduction and activities. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Barrera, Maria Cecilia and Josifovic, Aleksander and Robertson, John and Johnston, Blair and Brown, Cameron and Florence, Alastair (2022) Using machine learning to predict residence time distributions in Coiled Flow Inverter (CFI) reactors. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Prasad, Elke and Robertson, John and Halbert, Gavin (2022) An additive manufacturing MicroFactory : overcoming limitations of pharmaceutical formulations. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Solid dispersions : improving drug performance through tablet micro-structure design. In: American Association of Pharmaceutical Scientists 2021, 2021-10-17 - 2021-10-20, Boston Convention & Exhibition Center.

Prasad, Elke and Halbert, Gavin and Robertson, John (2021) Opening up the pharmaceutical formulation space for Additive Manufacturing. In: EUPAT 10 (2021) pan-European Science Conference on QbD & PAT, 2021-10-04 - 2021-10-06, Virtual Conference.

Halbert, Gavin and Prasad, Elke and Robertson, John (2021) Continuous pharmaceutical processes new applications – old challenges. In: 4th International Symposium on Pharmaceutical Engineering Research - SPheRe, 2021-09-15 - 2021-09-17, TU Braunschweig.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Mechanical characterisation of an FDM 3D printing process. In: Virtual PharmSci, 2021-09-07 - 2021-09-09.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Printability of pharmaceutical polymers in FDM 3D printers. In: Virtual PharmSci, 2021-09-07 - 2021-09-09.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Quality control test for pharmaceutical feedstock material for FDM 3D printers. In: Virtual PharmSci, 2021-09-07 - 2021-09-09.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2020) Improving consistency for a Mefenamic acid immediate release formulation. In: CMAC Annual Open Day, 2020-10-21 - 2020-10-22, Virtual event.

Prasad, E. and Robertson, J. and Halbert, G. (2019) Enabling future manufacture of dose forms: screening tools for an HME-3D printing process. In: CMAC UK Showcase, 2019-10-23 - 2019-10-23, CMAC Future Manufacturing Research Hub, Strathclyde Institute of Pharmacy and Biomedical Sciences.

Prasad, E. and Robertson, J. and Halbert, G. (2019) HUB Microfactory – PPA1 – Mefenamic acid – HME – 3D printing process stream. In: CMAC DTC Summer school, 2019-06-12 - 2019-06-14, Hampden Park.

Prasad, E. and Robertson, J. and Brown, C. and Jolliffe, H. and Florence, A. and Halbert, G. (2018) Microfactory – Blend – Compression - Performance test. In: CMAC Annual Open Day, 2018-10-25 - 2018-10-26.

Prasad, Elke and Islam, Muhammad and Robertson, John and Halbert, Gavin (2017) Example use of screening and analytical tools for secondary processing. In: CMAC Tier1 Showcase, 2017-11-09 - 2017-11-09, University of Strathclyde, SIPBS, CMAC.

Rajniak, Pavol and Fuentes-Gari, Maria and Mitchell, Niall and Islam, Muhammad Tariqul and Robertson, John and Bermingham, Sean K (2016) Modelling of co-rotating twin-screw extruders in the pharmaceutical industry I : single component model. In: 2016 AIChE Annual Meeting, 2016-11-13 - 2016-11-18, San Francisco.

Islam, M. T. and Robertson, J. and Tahir, F. and Florence, A. (2016) Investigating processing window of Affinisol™ and Plasdone™ - S630 polymers during hot-melt extrusion (for 3D printing by fused deposition modelling). In: 7th APS International PharmSci Conference, 2016-09-05 - 2016-09-07, University of Strathclyde.

Islam, M.T. and Robertson, J. and Florence, A.J. (2016) Initial assessment of hot-melt extrusion for processing API with a wide range of physical properties to form consistent solid dispersion : HPMC-Affinisol paracetamol system. In: 2016 AAPS Annual meeting and exposition, 2016-11-13 - 2016-11-17, Colorado Convention Center. (In Press)