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Article

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2024) An Additive Manufacturing MicroFactory : overcoming brittle material failure and improving product performance through tablet microstructure control for an immediate release dose form. Polymers, 16 (18). 2566. ISSN 2073-4360

Brown, Cameron J. and McGinty, John and Islam, Muhammad T. and Rajoub, Nazer and Arjmandi-Tash, Omid and Ottoboni, Sara and Shahid, Muhid and Urwin, Stephanie J. and Lee, Ye Seol and Chong, Magdalene W. S. and Papathanasiou, Foteini and Prakash, Aruna S. and Prasad, Elke and Spence, Bronwyn and Sefcik, Jan and Robertson, John and Smith, Rachel and Litster, James D. and Price, Chris J. and Nordon, Alison and Adjiman, Claire S. and Florence, Alastair J. (2024) Integrated continuous process design for crystallisation, spherical agglomeration, and filtration of lovastatin. Journal of Pharmaceutical Innovation, 19 (2). 9. ISSN 1939-8042

Prasad, Elke and Robertson, John and Florence, Alastair J. and Halbert, Gavin W. (2023) Expanding the pharmaceutical formulation space in material extrusion 3D printing applications. Additive Manufacturing, 77. 103803. ISSN 2214-8604

Urwin, Stephanie J. and Chong, Magdalene W.S. and Li, Wei and McGinty, John and Mehta, Bhavik and Ottoboni, Sara and Pathan, Momina and Prasad, Elke and Robertson, Murray and McGowan, Mark and al-Attili, Mais and Gramadnikova, Ekaterina and Siddique, Mariam and Houson, Ian and Feilden, Helen and Benyahia, Brahim and Brown, Cameron J. and Halbert, Gavin W. and Johnston, Blair and Nordon, Alison and Price, Chris J. and Reilly, Chris D. and Sefcik, Jan and Florence, Alastair J. (2023) Digital process design to define and deliver pharmaceutical particle attributes. Chemical Engineering Research and Design, 196. pp. 726-749. ISSN 0263-8762

Walsh, Erin and Maclean, Natalie and Turner, Alice and Alsuleman, Moulham and Prasad, Elke and Halbert, Gavin and ter Horst, Joop H. and Markl, Daniel (2022) Manufacture of tablets with structurally-controlled drug release using rapid tooling injection moulding. International Journal of Pharmaceutics, 624. 121956. ISSN 1873-3476

Polyzois, Hector and Guo, Rui and Srirambhatla, Vijay K. and Warzecha, Monika and Prasad, Elke and Turner, Alice and Halbert, Gavin W. and Keating, Patricia and Price, Sarah L. and Florence, Alastair J. (2022) Crystal structure and twisted aggregates of oxcarbazepine form III. Crystal Growth and Design, 22 (7). pp. 4146-4156. ISSN 1528-7483

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2022) Mefenamic acid solid dispersions : impact of formulation composition on processing parameters, product properties and performance. International Journal of Pharmaceutics, 616. 121505. ISSN 1873-3476

Prasad, Elke and Robertson, John and Halbert, Gavin (2020) Improving consistency for a Mefenamic acid immediate release formulation. Journal of Pharmaceutical Sciences. ISSN 0022-3549

Prasad, Elke and Islam, Muhammad T. and Goodwin, Daniel J. and Megarry, Andrew J. and Halbert, Gavin W. and Florence, Alastair J. and Robertson, John (2019) Development of a hot-melt extrusion (HME) process to produce drug loaded Affinisol™ 15LV filaments for Fused Filament Fabrication (FFF) 3D printing. Additive Manufacturing, 29. 100776. ISSN 2214-8604

Brown, Cameron J. and McGlone, Thomas and Yerdelen, Stephanie and Srirambhatla, Vijay and Mabbott, Fraser and Gurung, Rajesh and Briuglia, Maria L. and Ahmed, Bilal and Polyzois, Hector and McGinty, John and Perciballi, Francesca and Fysikopoulos, Dimitris and Macfhionnghaile, Pól and Siddique, Humera and Raval, Vishal and Harrington, Tomás S. and Vassileiou, Antony D. and Robertson, Murray and Prasad, Elke and Johnston, Andrea and Johnston, Blair and Nordon, Alison and Srai, Jagjit S. and Halbert, Gavin and ter Horst, Joop H. and Price, Chris J. and Rielly, Chris D. and Sefcik, Jan and Florence, Alastair J. (2018) Enabling precision manufacturing of active pharmaceutical ingredients : workflow for seeded cooling continuous crystallisations. Molecular Systems Design & Engineering, 2018 (3). pp. 518-549. ISSN 2058-9689

Halbert, Gavin and Elliott, Moira and Ford, Steven and Dick, Lindsay and Schmidt, Elke (2013) Improved pharmaceutical stability of a boronphenylalanine mannitol formulation for boron neutron capture therapy. European Journal of Pharmaceutical Sciences, 48. pp. 735-739. ISSN 0928-0987

Elliott, Moira and Ford, S J and Prasad, E and Dick, L J and Farmer, H and Hogg, P J and Halbert, G W (2012) Pharmaceutical development of the novel arsenical based cancer therapeutic GSAO for phase I clinical trial. International Journal of Pharmaceutics, 426 (1-2). pp. 67-75. ISSN 1873-3476

Schmidt, Elke and Dooley, Neil and Ford, Steven J. and Elliott, Moira and Halbert, Gavin W. (2012) Physicochemical investigation of the influence of saccharide-based parenteral formulation excipients on l-p-boronphenylalanine solubilisation for boron neutron capture therapy. Journal of Pharmaceutical Sciences, 101 (1). pp. 223-232. ISSN 0022-3549

Schmidt, E. and Ford, S. and Dooley, N. and Elliot, M. and Halbert, G. (2010) Effects of substituting Fructose by Mannitol in a pharmaceutical formulation. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1428-1429. ISSN 0022-3573

Dooley, N. and Ford, S. J. and Prasad, Elke and Elliott, M. and Halbert, Gavin (2010) Experimental scrutiny and project timelines : an example. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1208-1209. ISSN 0022-3573

Book Section

Jolliffe, Hikaru G. and Papathanasiou, Foteini and Prasad, Elke and Halbert, Gavin and Robertson, John and Brown, Cameron J. and Florence, Alastair J.; (2019) Improving the prediction of multi-component tablet properties from pure component parameters. In: 29th European Symposium on Computer Aided Chemical Engineering. Computer Aided Chemical Engineering, 46 . Elsevier, NLD, pp. 883-888. ISBN 9780128186350

van der Walle, Christopher F. and Schmidt, Elke; van der Walle, Chris F., ed. (2011) Modulation of the intestinal tight junctions using bacterial enterotoxins. In: Peptide and Protein Delivery. Elsevier, London, pp. 195-220. ISBN 9780123849359

Conference or Workshop Item

Prasad, Elke and Robertson, John and Halbert, Gavin (2024) Additive manufacturing MicroFactory for amorphous solid dispersion formulations. In: CMAC Showcase 2024, 2024-09-16 - 2024-09-16, TIC.

Prasad, Elke and Hueckman, Jill and Bordos, Ecaterina and Robertson, John and Halbert, Gavin W. (2024) 3D printing MicroFactory for amorphous solid dispersion formulations. In: CMAC Summer School 2024, 2023-07-10 - 2024-07-14.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2023) The EPSRC future manufacturing research HUB : 3D printing microfactory. In: CMAC Open Days 2023, 2023-11-14 - 2023-11-16, Technology & Innovation Centre, 99 George Street.

Prasad, Elke; Robertson, John and Halbert, Gavin, eds. (2023) Linking 3DP manufacturing with SIFT-MS volatiles organic compound analysis. In: CMAC Open Days 2023, 2023-11-14 - 2023-11-16, Technology & Innovation Centre, 99 George Street.

Prasad, Elke and Bordos, Ecaterina and Langford, Vaughan and Perkins, Mark and Robertson, John and Halbert, Gavin W. (2023) Linking 3DP manufacturing with SIFT-MS volatiles organic compound analysis. In: AAPS 2023 PHARMSCI 360, 2023-10-22 - 2023-10-25, Orange County Convention Center.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2023) 3D Printing MicroFactory. In: CMAC Summer School, 2023-06-12 - 2023-06-16.

Prasad, Elke and Robertson, John and Halbert, Gavin (2023) An Novel Additive Manufacturing Micro-factory: Overcoming limitations of pharmaceutical formulations. In: SIPBS Research Day, 2023-06-01 - 2023-06-01.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2022) Identifying the operating space and repeatability of a novel filament free FDM printer. In: AAPS 2022 Pharm Sci 360, 2022-10-16 - 2022-10-19, USA.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2022) Printability of pharmaceutical Fused Deposition Modeling (FDM) feedstock material : mechanical characterisation of FDM filaments and the FDM 3D printing process. In: AAPS 2022 Pharm Sci 360, 2022-10-16 - 2022-10-19, USA.

Vivattanaseth, Pattavet and Chong, Magdalene and Prasad, Elke and Halbert, Gavin and Robertson, John and McFarlan, Catriona and Nordon, Alison (2022) Application of multivariate curve resolution to in situ THz - Raman spectroscopy of amorphous solid dispersions in pharmaceutical products. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Chong, Magdalene and Brown, Cameron and Mustoe, Chantal and McGinty, John and Li, Wei and Pathan, Momina and Ottoboni, Sara and Prasad, Elke and Robertson, Murray and Mehta, Bhavik and McGowan, Mark and Siddique, Humera and Raval, Vishal and Pereira Diaz, Laura and Siddique, Mariam and Eales, William and Turner, Alice and Johnston, Blair and Robertson, John and Halbert, Gavin and Price, Chris and Benyahia, Brahim and Rielly, Chris and Sefcik, Jan and Nordon, Alison and McGlone, Thomas and Smith, Kenneth and Feilden, Helen and Houson, Ian and Florence, Alastair (2022) The CMAC MicroFactory : mefenamic acid. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Li, Wei and Benyahia, Brahim and Rielly, Chris D. and McGinty, John and Chong, Magdalene W. S. and Ottoboni, Sara and Pathan, Momina and McGowan, Mark and Prasad, Elke and Robertson, Murray (2022) Model driven crystallization design and development for mefenamic acid. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Prasad, Elke and Robertson, John and Halbert, Gavin (2022) An additive manufacturing MicroFactory : overcoming limitations of pharmaceutical formulations. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Solid dispersions : improving drug performance through tablet micro-structure design. In: American Association of Pharmaceutical Scientists 2021, 2021-10-17 - 2021-10-20, Boston Convention & Exhibition Center.

Prasad, Elke and Halbert, Gavin and Robertson, John (2021) Opening up the pharmaceutical formulation space for Additive Manufacturing. In: EUPAT 10 (2021) pan-European Science Conference on QbD & PAT, 2021-10-04 - 2021-10-06, Virtual Conference.

Halbert, Gavin and Prasad, Elke and Robertson, John (2021) Continuous pharmaceutical processes new applications – old challenges. In: 4th International Symposium on Pharmaceutical Engineering Research - SPheRe, 2021-09-15 - 2021-09-17, TU Braunschweig.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Mechanical characterisation of an FDM 3D printing process. In: Virtual PharmSci, 2021-09-07 - 2021-09-09.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Printability of pharmaceutical polymers in FDM 3D printers. In: Virtual PharmSci, 2021-09-07 - 2021-09-09.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Quality control test for pharmaceutical feedstock material for FDM 3D printers. In: Virtual PharmSci, 2021-09-07 - 2021-09-09.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2020) Improving consistency for a Mefenamic acid immediate release formulation. In: CMAC Annual Open Day, 2020-10-21 - 2020-10-22, Virtual event.

Prasad, E. and Robertson, J. and Halbert, G. (2019) Enabling future manufacture of dose forms: screening tools for an HME-3D printing process. In: CMAC UK Showcase, 2019-10-23 - 2019-10-23, CMAC Future Manufacturing Research Hub, Strathclyde Institute of Pharmacy and Biomedical Sciences.

Prasad, E. and Robertson, J. and Halbert, G. (2019) HUB Microfactory – PPA1 – Mefenamic acid – HME – 3D printing process stream. In: CMAC DTC Summer school, 2019-06-12 - 2019-06-14, Hampden Park.

Prasad, E. and Robertson, J. and Brown, C. and Jolliffe, H. and Florence, A. and Halbert, G. (2018) Microfactory – Blend – Compression - Performance test. In: CMAC Annual Open Day, 2018-10-25 - 2018-10-26.

Prasad, Elke and Islam, Muhammad and Robertson, John and Halbert, Gavin (2017) Example use of screening and analytical tools for secondary processing. In: CMAC Tier1 Showcase, 2017-11-09 - 2017-11-09, University of Strathclyde, SIPBS, CMAC.

Prasad, Elke and Halbert, Gavin H. (2016) Online UV imaging of API-excipient mixtures during dissolution. In: CMAC Internal Research Day, 2016-04-29, University of Strathclyde.

Bowornsaksit, C. and Lamprou, D. and Halbert, G. and Prasad, E. (2015) Preparation and characterisation of free flowing solid lipid based drug delivery systems using a twin screw extruder. In: CMAC Internal Research Day, 2015-09-25.

Prasad, Elke and Halbert, Gavin and Elliott, Moira (2013) Characterisation of a liquid-capsule-fill-formulation performance on an automated capsule filling machine (CFS1000). In: APS PharmSci 2013, 2013-09-02 - 2013-09-04, Heriot Watt University.

Elliott, M.A. and Prasad, E. and Ford, S.J. and Halbert, G.W. (2010) Experiences of melt fi ll production of Fenretinide/Lym-X-Sorb™ hard gelatin capsules for Phase I clinical trial. In: UK-PharmSci 2010 – The Science of Medicines, 2010-09-01 - 2010-09-03.