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Article

Visocky, Vladimir and Morris, Brian J. and Dunlop, John and Brandon, Nick and Sakata, Shuzo and Pratt, Judith A. (2024) Site‐specific inhibition of the thalamic reticular nucleus induces distinct modulations in sleep architecture. European Journal of Neuroscience, 59 (4). pp. 554-569. ISSN 0953-816X

Openshaw, Rebecca L. and Thomson, David M. and Bristow, Greg C. and Mitchell, Emma J. and Pratt, Judith A. and Morris, Brian J. and Dawson, Neil (2023) 16p11.2 deletion mice exhibit compromised fronto-temporal connectivity, GABAergic dysfunction, and enhanced attentional ability. Communications Biology, 6. 557. ISSN 2399-3642

Pratt, Judith A. and Robinson, Emma S. J. and Fernandes, Cathy and Heal, David and Stanford, S Clare (2022) Improving the validity and translation of preclinical research. Journal of Psychopharmacology, 36 (7). pp. 779-780. ISSN 1461-7285

Baudot, Alice D. and Wang, Victoria M.-Y. and Leach, Josh D. and O’Prey, Jim and Long, Jaclyn S. and Paulus-Hock, Viola and Lilla, Sergio and Thomson, David M. and Greenhorn, John and Ghaffar, Farah and Nixon, Colin and Helfrich, Miep H. and Strathdee, Douglas and Pratt, Judith and Marchesi, Francesco and Zanivan, Sara and Ryan, Kevin M. (2022) Glycan degradation promotes macroautophagy. Proceedings of the National Academy of Sciences, 119 (26). e2111506119. ISSN 0027-8424

Willis, Ashleigh and Pratt, Judith A. and Morris, Brian J. (2022) Enzymatic degradation of cortical perineuronal nets reverses GABAergic interneuron maturation. Molecular Neurobiology, 59 (5). pp. 2874-2893. ISSN 1559-1182

Openshaw, Rebecca L. and Pratt, Judith A. and Morris, Brian J. (2022) The schizophrenia risk gene Map2k7 regulates responding in a novel contingency-shifting rodent touchscreen gambling task. Disease Models & Mechanisms, 15 (3). dmm049310. ISSN 1754-8411

Thomson, David M and Mitchell, Emma J and Openshaw, Rebecca L and Pratt, Judith A and Morris, Brian J (2021) Mice lacking melatonin MT2 receptors exhibit attentional deficits, anxiety and enhanced social interaction. Journal of Psychopharmacology, 35 (10). pp. 1265-1276. ISSN 1461-7285

Thomson, David M. and Openshaw, Rebecca L. and Mitchell, Emma J. and Kouskou, Marianna and Millan, Mark J. and Mannoury la Cour, Clotilde and Morris, Brian J. and Pratt, Judith A. (2021) Impaired working memory, cognitive flexibility and reward processing in mice genetically lacking Gpr88 : evidence for a key role for Gpr88 in multiple cortico-striatal-thalamic circuits. Genes, Brain and Behavior, 20 (2). e12710. ISSN 1601-1848

Willis, Ashleigh and Pratt, Judith A and Morris, Brian J (2020) BDNF and JNK-signalling modulate cortical interneuron and perineuronal net development: implications for schizophrenia-linked 16p11.2 duplication syndrome. Schizophrenia Bulletin. sbaa139. ISSN 0586-7614

Mitchell, Emma J. and Thomson, David M. and Openshaw, Rebecca L. and Bristow, Greg C. and Dawson, Neil and Pratt, Judith A. and Morris, Brian J. (2020) Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model : a central role for gene environment interactions. Scientific Reports, 10 (1). 12303. ISSN 2045-2322

Mitchell, Emma J and Brett, Ros R and Armstrong, J Douglas and Sillito, Rowland R and Pratt, Judith A (2020) Temporal dissociation of phencyclidine-induced locomotor and social alterations in rats using an automated homecage monitoring system - implications for the 3Rs and preclinical drug discovery. Journal of Psychopharmacology, 34 (7). pp. 709-715. ISSN 1461-7285

Bristow, Greg C. and Thomson, David M. and Openshaw, Rebecca L. and Mitchell, Emma J. and Pratt, Judith A. and Dawson, Neil and Morris, Brian J. (2020) 16p11 duplication disrupts hippocampal-orbitofrontal-amygdala connectivity, revealing a neural circuit endophenotype for schizophrenia. Cell Reports, 31 (3). 107536. ISSN 2211-1247

Openshaw, Rebecca L. and Thomson, David M. and Thompson, Rhiannon and Penninger, Josef M and Pratt, Judith A and Morris, Brian J and Dawson, Neil (2020) Map2k7 haploinsufficiency induces brain imaging endophenotypes and behavioral phenotypes relevant to schizophrenia. Schizophrenia Bulletin, 46 (1). pp. 211-223. ISSN 0586-7614

Openshaw, Rebecca L. and Kwon, Jaedeok and McColl, Alison and Penninger, Josef M. and Cavanagh, Jonathan and Pratt, Judith A. and Morris, Brian J. (2019) JNK signalling mediates aspects of maternal immune activation : importance of maternal genotype in relation to schizophrenia risk. Journal of Neuroinflammation, 16 (1). 18. ISSN 1742-2094

Kouskou, Marianna and Thomson, David M. and Brett, Ros R. and Wheeler, Lee and Tate, Rothwelle J. and Pratt, Judith A. and Chamberlain, Luke H. (2018) Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse. Experimental Neurology, 308. pp. 35-46. ISSN 0014-4886

Willis, Ashleigh and Pratt, Judith A. and Morris, Brian J. (2018) Distortion of protein analysis in primary neuronal cultures by serum albumin from culture medium : a methodological approach to improve target protein quantification. Journal of Neuroscience Methods, 308. pp. 1-5. ISSN 0165-0270

Pratt, Judith and Dawson, Neil and Morris, Brain J. and Grent T'Jong, Tineke and Roux, Frederic and Uhlhaas, Peter J. (2017) Thalamo-cortical communication, glutamatergic neurotransmission and neural oscillations : a unique window into the origins of ScZ? Schizophrenia Research, 180. pp. 4-12. ISSN 0920-9964

Openshaw, R.L. and Thomson, D.M. and Penninger, J.M. and Pratt, J.A. and Morris, B.J. (2017) Mice haploinsufficient for Map2k7, a gene involved in neurodevelopment and risk for schizophrenia, show impaired attention, a vigilance decrement deficit and unstable cognitive processing in an attentional task : impact of minocycline. Psychopharmacology, 234 (2). pp. 293-305. ISSN 0033-3158

Pinnell, R C and Dempster, J and Pratt, J (2015) Miniature wireless recording and stimulation system for rodent behavioural testing. Journal of Neural Engineering, 12 (6). 066015. ISSN 1741-2552

Dawson, N and Kurihara, M and Thomson, DM and Winchester, CL and McVie, A and Hedde, JR and Randall, AD and Shen, S and Seymour, PA and Hughes, ZA and Dunlop, J and Brown, JT and Brandon, NJ and Morris, BJ and Pratt, JA (2015) Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1. Translational Psychiatry, 5. e569.

Dawson, Neil and Morris, Brian J and Pratt, Judith A (2015) Functional brain connectivity phenotypes for schizophrenia drug discovery. Journal of Psychopharmacology, 29 (2). pp. 169-177. ISSN 1461-7285

Pratt, Judith (2015) Schizophrenia in the 21st century : new insights and translation into improved therapies. Journal of psychopharmacology (Oxford, England), 29 (2). pp. 83-84. ISSN 1461-7285

Pratt, Judith A and Morris, Brian J (2015) The thalamic reticular nucleus : a functional hub for thalamocortical network dysfunction in schizophrenia and a target for drug discovery. Journal of Psychopharmacology, 29 (2). pp. 127-137. ISSN 1461-7285

Morris, B.J. and Pratt, J.A. (2014) Novel treatment strategies for schizophrenia from improved understanding of genetic risk. Clinical Genetics, 86 (5). pp. 401-411. ISSN 0009-9163

Winchester, Catherine L and Pratt, Judith A and Morris, Brian J (2014) Risk genes for schizophrenia : translational opportunities for drug discovery. Pharmacology and Therapeutics, 143 (1). pp. 34-50. ISSN 0163-7258

Dawson, Neil and McDonald, Martin and Higham, Desmond J and Morris, Brian J and Pratt, Judith A (2014) Subanesthetic ketamine treatment promotes abnormal interactions between neural subsystems and alters the properties of functional brain networks. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 39 (7). pp. 1786-1798. ISSN 1470-634X

Dawson, Neil and Xiao, Xiaolin and McDonald, Martin Dean and Higham, Desmond and Morris, Brian J. and Pratt, Judith (2014) Sustained NMDA receptor hypofunction induces compromised neural systems integration and schizophrenia-like alterations in functional brain networks. Cerebral Cortex, 24 (2). pp. 452-464.

Ewing, Samuel G and Porr, Bernd and Pratt, Judith A (2013) Deep brain stimulation of the mediodorsal thalamic nucleus yields increases in the expression of zif-268 but not c-fos in the frontal cortex. Journal of Chemical Neuroanatomy, 52. pp. 20-24. ISSN 1873-6300

Kirshenbaum, Greer S and Dawson, Neil and Mullins, Jonathan G L and Johnston, Tom H and Drinkhill, Mark J and Edwards, Ian J and Fox, Susan H and Pratt, Judith A and Brotchie, Jonathan M and Roder, John C and Clapcote, Steven J (2013) Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+,K+-ATPase α3 missense mutant mice. PLoS ONE, 8 (3). e60141. ISSN 1932-6203

Dawson, Neil and Morris, B.J. and Pratt, Judith (2013) Subanaesthetic ketamine treatment alters prefrontal cortex connectivity with thalamus and ascending subcortical systems. Schizophrenia Bulletin, 39 (2). pp. 366-377.

Winchester, Catherine and Ohzeki, Hiromitsu and Vouyiouklis, Demetrius and Thompson, Rhiannon and Yamagami, Keiji and Norrie, John and Hunter, Robert and Pratt, Judith and Morris, Brian J (2012) Converging evidence that sequence variations in the novel candidate gene MAP2K7 (MKK7) are functionally associated with schizophrenia. Human Molecular Genetics, 21 (22). pp. 4910-4921.

Pratt, Judith and Winchester, Catherine and Dawson, Neil and Morris, Brian (2012) Advancing schizophrenia drug discovery : optimizing rodent models to bridge the translational gap. Nature Reviews Drug Discovery, 11 (7). pp. 560-579. ISSN 1474-1784

Dawson, Neil and Thompson, Rhiannon J and McVie, Allan and Thomson, David M and Morris, Brian J. and Pratt, Judith (2012) Modafinil reverses phencyclidine-induced deficits in cognitive flexibility, cerebral metabolism, and functional brain connectivity. Schizophrenia Bulletin, 38 (3). pp. 457-474.

Steward, Lucinda J and Kennedy, Matthew D and Morris, Brian J and Pratt, Judith A (2012) Chronic phencyclidine (PCP)-induced modulation of muscarinic receptor mRNAs in rat brain : impact of antipsychotic drug treatment. Neuropharmacology, 62 (3). pp. 1554-1563.

Stenson, G. S. and Pratt, J. and Brett, R. (2011) Environment-environment interactions in a schizophrenia-related disease model : impact of poly ic and thc on the developing brain. Journal of Psychopharmacology, 25 (8 Supp). A68-A68. ISSN 1461-7285

Davies, C.L. and Thomson, D. M. and Morris, B. J. and Pratt, J. A. (2011) Impact of modafinil on acquisition and subsequent performance of pcp -treated rats in the 5 -choice serial reaction time task. Journal of Psychopharmacology, 25 (8 Supp). A71-A71. ISSN 1461-7285

Dawson, N. and McDonald, M. and Higham, D. J. and Morris, B. J. and Pratt, J. A. (2011) Subanaesthetic ketamine treatment alters prefrontal cortex functional connectivity and the properties of functional brain networks. Journal of Psychopharmacology, 25 (8). A63-A63. ISSN 1461-7285

Winchester, C. L. and Hamilton, G. M. and Morris, B. and Pratt, J. A. and Hunter, R. and Bailey, M.E.S (2011) Using next generation sequencing to investigate DPYSL2 gene variants in schizophrenia. Journal of Psychopharmacology, 25 (8 Supp). A67-A67. ISSN 1461-7285

Winchester, C. L. and Paterson, C. and Morris, B. and Glover, C. P. and Storey, J. and Hussein, I. and Pratt, J. A. (2011) Viral-mediated knockdown of ERBB4 in the rodent prefrontal cortex enhances cognitive performance. Journal of Psychopharmacology, 25 (8 Supp). A68-A68. ISSN 1461-7285

Xiao, Xiaolin and Dawson, Neil and MacIntyre, Lynsey and Morris, Brian J. and Pratt, Judith A. and Watson, David G. and Higham, Desmond J (2011) Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the generalized singular value decomposition. BMC Systems Biology, 5. 72. ISSN 1752-0509

Ledgerwood, Craig and Greenwood, Sam M. and Brett, R.R. and Pratt, J.A. and Bushell, T. (2011) Cannabidiol inhibits synaptic transmission in rat hippocampal cultures and slices via multiple receptor pathways. British Journal of Pharmacology, 162 (1). pp. 286-294. ISSN 1476-5381

Thomson, David M and McVie, Allan and Morris, Brian J and Pratt, Judith A (2011) Dissociation of acute and chronic intermittent phencyclidine-induced performance deficits in the 5-choice serial reaction time task: influence of clozapine. Psychopharmacology, 213 (4). pp. 681-95. ISSN 0033-3158

Sousa, Vasco C and Assaife-Lopes, Natália and Ribeiro, Joaquim A and Pratt, Judith A and Brett, Ros R and Sebastião, Ana M (2011) Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration : implications for the effects of Δ9-tetrahydrocannabinol on spatial memory. Neuropsychopharmacology, 36 (2). pp. 472-487. ISSN 1470-634X

Dawson, Neil and Higham, Des and Pratt, Judith and Morris, Brian (2010) Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in schizophrenia. Schizophrenia Research, 117 (2-3). pp. 234-235. ISSN 0920-9964

Henriquez, Selina A. and Thompson, David M. and Henriquez, Fiona L. and Alexander, James and Pratt, Judith and Brett, Ros and Roberts, Craig W. (2010) Is there a relationship between toxoplasma gondii and psychiatric disorders? Schizophrenia Research, 117 (2-3). pp. 389-390. ISSN 0920-9964

Henriquez, S.A. and Brett, Ros and Alexander, J. and Pratt, Judith and Roberts, C.W. (2009) Neuropsychiatric disease and toxoplasma gondii infection. Neuroimmunomodulation, 16 (2). pp. 122-133. ISSN 1021-7401

Thomson, D.M. and Mcvie, A. and Morris, B.J. and Pratt, J.A. (2008) Clozapine produces modest effects on pcp-induced performance deficits in the 5-choice serial reaction time task. Behavioural Pharmacology, 19 (5-6). pp. 655-656. ISSN 0955-8810

Egerton, Alice and Reid, Lee and McGregor, Sandie and Cochran, Susan M. and Morris, Brian J. and Pratt, Judith (2008) Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in rats. Psychopharmacology, 198 (1). pp. 37-49. ISSN 0033-3158

Pratt, J.A. and Winchester, C. and Egerton, A. and Cochran, S.M. and Morris, B.J. (2008) Modelling prefrontal cortex deficits in schizophrenia: implications for treatment. British Journal of Pharmacology, 153. S465-S470. ISSN 1476-5381

Suckling, C.J. and Murphy, J.A. and Khalaf, A.I. and Zhou, S. and Lizos, D.E. and Nguyen Van Nhien, A. and Yasumatsu, H. and McVie, A. and Young, L.C. and McCraw, C. and Waterman, P.G. and Morris, B.J. and Pratt, J.A. and Harvey, A. (2007) M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds. Bioorganic and Medicinal Chemistry Letters, 17 (9). pp. 2649-2655. ISSN 0960-894X

Allison, C. and Pratt, J.A. (2006) Differential effects of two chronic diazepam treatment regimes on withdrawal anxiety and aMPA receptor characteristics. Neuropsychopharmacology, 31. pp. 602-619. ISSN 1470-634X

Egerton, A.D. and Allison, C. and Brett, R.R. and Pratt, J.A. (2006) Cannabinoids and prefrontal cortical function : insights from preclinical studies. Neuroscience and Biobehavioral Reviews, 30 (5). pp. 680-695. ISSN 0149-7634

Egerton, A.D. and Brett, R.R. and Pratt, J.A. (2005) Acute ∆9-tetrahydrocannabinol-induced deficits in reversal learning: neural correlates of affective inflexibility. Neuropsychopharmacology, 30. pp. 1895-1905. ISSN 1470-634X

Allison, C. and Pratt, J.A. and Ripley, T. and Stephens, D.N. (2005) AMPA receptor autoradiography in mouse brain following single and repeated withdrawal from diazepam. European Journal of Neuroscience, 21. pp. 1045-1056. ISSN 0953-816X

Egerton, A.D. and Reid, L. and McKerchar, C. and Morris, B.J. and Pratt, J.A. (2005) Impairment in perceptual attentional set shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia. Psychopharmacology, 179. pp. 77-84. ISSN 0033-3158

Cochran, S.M. and Steward, L. and Kennedy, M.D. and McKerchar, C. and Pratt, J.A. and Morris, B.J. (2003) Induction of metabolic hypofunction and neurochemical deficits after chronic intermittent exposure to phencyclidine: differential modulation by antipsychotic drugs. Neuropsychopharmacology, 28. pp. 265-275. ISSN 1470-634X

Brett, Ros and MacKenzie, Fiona and Pratt, Judith (2001) [DELTA]9-tetrahydrocannabinol-induced alterations in limbic system glucose use in the rat. NeuroReport, 12 (16). pp. 3573-3577. ISSN 0959-4965

Cochran, S M and Harvey, A L and Pratt, J A (2001) Regionally selective alterations in local cerebral glucose utilization evoked by charybdotoxin, a blocker of central voltage-activated K+-channels. European Journal of Neuroscience, 14 (9). pp. 1455-1463. ISSN 0953-816X

Book Section

Pratt, Judith and Hall, Jeremy; (2018) Biomarkers in neuropsychiatry : a prospect for the twenty-first century? In: Current Topics in Behavioral Neurosciences. Current Topics in Behavioral Neurosciences . Springer, Berlin.

Pratt, Judith A and Morris, Brian and Dawson, Neil; (2018) Deconstructing schizophrenia : advances in preclinical models for biomarker identification. In: Current Topics in Behavioral Neurosciences. Current Topics in Behavioral Neurosciences . Springer, Berlin.

Conference or Workshop Item

Weir, Natalie and Kernaghan, David and Watson, Margaret and Akram, Gazala and Maxwell, Margaret and Pratt, Judith (2023) Building the evidence base for community pharmacy depression services. In: Mental Health Care Futures, 2023-05-12, University of Strathclyde.

Brett, R.R. and Pratt, J.A. and Bushell, T. and Ledgerwood, Craig (2008) Exposure of cultured hippocampal neurones to cannabidiol does not induce cell death but inhibits synaptic activity. In: 18th Annual Symposium of the International Cannabinoid Research Society, 2008-06-25 - 2008-06-29. (Unpublished)