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Article

Binici, Burcu and Rattray, Zahra and Zinger, Assaf and Perrie, Yvonne (2025) Exploring the impact of commonly used ionizable and pegylated lipids on mRNA-LNPs : a combined in vitro and preclinical perspective. Journal of Controlled Release, 377. pp. 162-173. ISSN 0168-3659

Cunningham, Margaret R. and Rattray, Nicholas J.W. and McFadden, Yvonne and Berardi, Domenica and Daramy, Karim and Kelly, Patricia E. and Galbraith, Allison and Lochiel, Isobel and Mills, Lorraine and Scott, Yvonne and Chalmers, Susan and Lannigan, Alison and Rattray, Zahra (2024) Recounting the untold stories of breast cancer patient experiences : lessons learned from a patient-public involvement and engagement (PPIE) storytelling event. International Journal of Pharmacy Practice, 32 (6). pp. 515-523. riae052. ISSN 2042-7174

Armstrong, Georgina Bethany and Roche, Aisling and Lewis, William and Rattray, Zahra (2024) Reconciling predicted and measured viscosity parameters in high concentration therapeutic antibody solutions. mAbs, 16 (1). 2438172.

Al Sultan, Abdullah and Rattray, Zahra and Rattray, Nicholas J. W. (2024) Integrative analysis of toxicometabolomics and toxicoproteomics data : new molecular insights into thiazolidinedione-induced cardiotoxicity. Metabolomics, 21 (1). 1. ISSN 1573-3882

Armstrong, Georgina Bethany and Burley, Glenn A. and Lewis, William and Rattray, Zahra (2024) Assessing the manufacturability and critical quality attribute profiles of anti-IL-8 immunoglobulin G mutant variants. Molecular Pharmaceutics, 21 (12). 6423–6432. ISSN 1543-8384

Armstrong, Georgina B. and Shah, Vidhi and Sanches, Paula and Patel, Mitul and Casey, Ricky and Jamieson, Craig and Burley, Glenn A. and Lewis, William and Rattray, Zahra (2024) A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles. Computational and Structural Biotechnology Journal, 23. pp. 2345-2357. ISSN 2001-0370

van den Driest, Lisa and Kelly, Patricia and Marshall, Alan and Johnson, Caroline H. and Lasky-Su, Jessica and Lannigan, Alison and Rattray, Zahra and Rattray, Nicholas J.W. (2024) A gap analysis of UK biobank publications reveals SNPs associated with intrinsic subtypes of breast cancer. Computational and Structural Biotechnology Journal, 23. pp. 2200-2210. ISSN 2001-0370

McMillan, Caitlin and Druschitz, Amy and Rumbelow, Stephen and Borah, Ankita and Binici, Burcu and Rattray, Zahra and Perrie, Yvonne (2024) Tailoring lipid nanoparticle dimensions through manufacturing processes. RSC Pharmaceutics, 1 (4). pp. 841-853. ISSN 2976-8713

Davidson, Callum G and Abdulrahman, Rand and Punnabhum, Panida and Cairns, Michael and Rattray, Nicholas J W and Capomaccio, Robin and Treacher, Kevin and Perrie, Yvonne and Rattray, Zahra (2024) The use of orthogonal analytical approaches to profile lipid nanoparticle physicochemical attributes. Nano Futures, 8 (3). 035001. ISSN 2399-1984

Daramy, Karim and Punnabhum, Panida and Hussain, Muattaz and Minelli, Caterina and Pei, Yiwen and Rattray, Nicholas J.W. and Perrie, Yvonne and Rattray, Zahra (2024) Nanoparticle isolation from biological media for protein corona analysis : the impact of incubation and recovery protocols on nanoparticle properties. Journal of Pharmaceutical Sciences, 113 (9). pp. 2826-2836. ISSN 0022-3549

Armstrong, Georgina and Lewis, Alan and Shah, Vidhi and Taylor, Paul and Jamieson, Craig J. and Burley, Glenn A. and Lewis, Will and Rattray, Zahra (2024) A first insight into the developability of an Immunoglobulin G3 : a combined computational and experimental approach. ACS Pharmacology & Translational Science, 7 (8). pp. 2439-2451. ISSN 2575-9108

Al Sultan, Abdullah and Rattray, Zahra and Rattray, Nicholas J. W. (2024) Cytotoxicity and toxicoproteomics analysis of thiazolidinedione exposure in human-derived cardiomyocytes. Journal of Applied Toxicology, 44 (8). pp. 1214-1235. ISSN 0260-437X

Binici, Burcu and Rattray, Zahra and Schroeder, Avi and Perrie, Yvonne (2024) The role of biological sex in pre-clinical (mouse) mRNA vaccine studies. Vaccines, 12 (3). 282. ISSN 2076-393X

Al Sultan, Abdullah and Rattray, Zahra and Rattray, Nicholas J. W. (2024) Toxicometabolomics-based cardiotoxicity evaluation of Thiazolidinedione exposure in human-derived cardiomyocytes. Metabolomics, 20 (2). 24. ISSN 1573-3890

Abdulrahman, Rand and Ibrahem, Huda and Mahmood, Amna and Treacher, Kevin and Vasey, Catherine and Capomaccio, Robin and Perrie, Yvonne and Rattray, Zahra (2023) Assessing lipid nanoparticle protein corona formation and cytocompatibility. British Journal of Pharmacy, 8 (2). 1398. ISSN 2058-8356

Kelly, Patricia E. and Jene Ng, H and Farrell, Gillian and McKirdy, Shona and Russell, Richard K. and Hansen, Richard and Rattray, Zahra and Gerasimidis, Konstantinos and Rattray, Nicholas J. W. (2022) An optimised monophasic faecal extraction method for LC-MS analysis and its application in gastrointestinal disease. Metabolites, 12 (11). 1110. ISSN 2218-1989

Daramy, Karim and Walker, Joshua and Pei, Yiwen and Minelli, Caterina and Perrie, Yvonne and Rattray, Zahra (2022) Investigating the impact of shear flow on nanoparticle-protein interactions. British Journal of Pharmacy, 7 (2). pp. 51-52. ISSN 2058-8356

Daramy, Karim and Punnabhum, Panida and Walker, Joshua and Bindhu Syammohan, Syampriya and Rattray, Zahra (2022) The application of field-flow fractionation to the analysis of nanomedicines. British Journal of Pharmacy, 7 (2). ISSN 2058-8356

Cai, Yuping and Shen, Xinyi and Lu, Lingeng and Yan, Hong and Huang, Huang and Gaule, Patricia and Muca, Engjel and Theriot, Casey M. and Rattray, Zahra and Rattray, Nicholas J. W. and Lu, Jun and Ahuja, Nita and Zhang, Yawei and Paty, Philip B. and Khan, Sajid A. and Johnson, Caroline H. (2022) Bile acid distributions, sex-specificity, and prognosis in colorectal cancer. Biology of Sex Differences, 13 (1). 61. ISSN 2042-6410

Abdullah, Mahmud O. and Zeng, Run X. and Margerum, Chelsea L. and Papadopoli, David and Monnin, Cian and Punter, Kaylee B. and Chu, Charles and Al-Rofaidi, Mohammad and Al-Tannak, Naser F. and Berardi, Domenica and Rattray, Zahra and Rattray, Nicholas J.W. and Abraham, Sheela A. and Eskelinen, Eeva-Liisa and Watson, David G. and Avizonis, Daina and Topisirovic, Ivan and Chan, Edmond Y.W. (2022) Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids. Cell Reports, 40 (7). p. 111198. 111198. ISSN 2211-1247

Alnoumas, Layla and Van Den Driest, Lisa and Apczynski, Zoe and Lannigan, Alison and Johnson, Caroline H. and Rattray, Nicholas J. W. and Rattray, Zahra (2022) Evaluation of the role of KPNA2 mutations in breast cancer prognosis using bioinformatics datasets. BMC Cancer, 22 (1). p. 874. 874. ISSN 1471-2407

Berardi, Domenica and Hunter, Yasmin and Van Den Driest, Lisa and Farrell, Gillian and Rattray, Nicholas J. W. and Rattray, Zahra (2022) The differential metabolic signature of breast cancer cellular response to olaparib treatment. Cancers, 14 (15). 3661. ISSN 2072-6694

Van Den Driest, Lisa and Johnson, Caroline H. and Rattray, Nicholas J. W. and Rattray, Zahra (2022) Development of an accessible gene expression bioinformatics pipeline to identify driver mutations of colorectal cancer. Alternatives to Laboratory Animals, 50 (4). pp. 282-292. ISSN 2632-3559

Malewicz, Nathalie M. and Rattray, Zahra and Oeck, Sebastian and Jung, Sebastian and Escamilla-Rivera, Vicente and Chen, Zeming and Tang, Xiangjun and Zhou, Jiangbing and LaMotte, Robert H. (2022) Topical capsaicin in PLGA NPs decreases acute itch and heat pain. International Journal of Molecular Sciences, 23 (9). 5275. ISSN 1422-0067

van der Walle, Christopher F. and Dufès, Christine and Desai, Arpan S. and Kerby, Julie and Broadhead, Joanne and Tam, Alice and Rattray, Zahra (2022) Report on webinar series cell and gene therapy : from concept to clinical use. Pharmaceutics, 14 (1). 168. ISSN 1999-4923

Rattray, Zahra and Deng, Gang and Zhang, Shenqi and Shirali, Anupama and May, Christopher K. and Chen, Xiaoyong and Cuffari, Benedette J. and Liu, Jun and Zou, Pan and Rattray, Nicholas J.W. and Johnson, Caroline H. and Dubljevic, Valentina and Campbell, James A. and Huttner, Anita and Baehring, Joachim M. and Zhou, Jiangbing and Hansen, James E. (2021) ENT2 facilitates brain endothelial cell penetration and blood-brain barrier transport by a tumor-targeting anti-DNA autoantibody. JCI Insight, 6 (14). e145875. ISSN 2379-3708

Cai, Yuping and Rattray, Nicholas J. W. and Zhang, Qian and Mironova, Varvara and Santos-Neto, Alvaro and Hsu, Kuo Shun and Muca, Engjel and Rosen Vollmar, Ana K. and Hsu, Kuo-Shun and Rattray, Zahra and Cross, Justin R. and Zhang, Yawei and Batty, Philip B. and Khan, Sajid A. and Johnson, Caroline H. (2020) Tumor tissue-specific biomarkers of colorectal cancer by anatomic location and stage. Metabolites, 10 (6). 257. ISSN 2218-1989

Patterson, Claire and Murphy, Dean and Irvine, Sarah and Connor, Leigh and Rattray, Zahra (2020) Novel application of synchrotron x-ray computed tomography for ex-vivo imaging of subcutaneously-injected polymeric microsphere suspension formulations. Pharmaceutical Research, 37 (6). 97. ISSN 0724-8741

Cai, Yuping and Rattray, Nicholas J. W. and Zhang, Qian and Mironova, Varvara and Santos-Neto, Alvaro and Hsu, Kuo-Shun and Rattray, Zahra and Cross, Justin R. and Zhang, Yawei and Paty, Philip B. and Khan, Sajid A. and Johnson, Caroline H. (2020) Sex differences in colon cancer metabolism reveal a novel subphenotype. Scientific Reports, 10. 4905. ISSN 2045-2322

Rattray, Nicholas J.W. and Trivedi, Drupad K. and Xu, Yun and Chandola, Tarani and Johnson, Caroline H. and Marshall, Alan D. and Mekli, Krisztina and Rattray, Zahra and Tampubolon, Gindo and Vanhoutte, Bram and White, Iain R. and Wu, Frederick C.W. and Pendleton, Neil and Nazroo, James and Goodacre, Royston (2019) Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty. Nature Communications, 10 (1). 5027. ISSN 2041-1723

Rattray, Zahra and Dubljevic, Valentina and Rattray, Nicholas and Greenwood, Deanne L. and Johnson, Caroline H. and Campbell, James A. and Hansen, James E. (2018) Re-engineering and evaluation of anti-DNA autoantibody 3E10 for therapeutic applications. Biochemical and Biophysical Research Communications, 496 (3). pp. 858-864. ISSN 1090-2104

Johnson, Caroline H. and Santidrian, Antonio F. and LeBoeuf, Sarah E. and Kurzy, Michael E. and Rattray, Nicholas and Rattray, Zahra and Warth, Benedikt and Ritland, Melissa and Hoang, Linh T. and Loriot, Celine and Higa, Jason and Hansen, James E. and Felding, Brunhilde H. and Siuzdak, Gary (2017) Metabolomics guided pathway analysis reveals link between cancer metastasis, cholesterol sulfate, and phospholipids. Cancer and Metabolism, 5 (1). ISSN 2049-3002

Shah, Maryam and Rattray, Zahra and Day, Katie and Uddin, Shahid and Curtis, Robin and van der walle, Christopher F. and Pluen, Alain (2017) Evaluation of aggregate and silicone-oil counts in pre-filled siliconized syringes: An orthogonal study characterising the entire subvisible size range. International Journal of Pharmaceutics, 519 (1-2). pp. 58-66. ISSN 1873-3476

Book Section

Rattray, Zahra and Zindy, Egor and Buzza, Karen M. and Pluen, Alain; McManus, Jennifer J., ed. (2019) Evaluation of temporal aggregation processes using spatial intensity distribution analysis. In: Protein Self-Assembly. Methods in Molecular Biology . Springer, New York, NY, pp. 141-155. ISBN 9781493996780

Conference or Workshop Item

Davidson, Callum G. and Punnabhum, Panida and Farrell, Gillian and Perrie, Yvonne and Rattray, Zahra (2024) High-resolution orthogonal techniques for separating and detecting impurities in antisense oligonucleotide therapeutics. In: JPAG Pharmaceutical Analysis Research Awards and Careers Fair 2024, 2024-11-12 - 2024-11-12.

Punnabhum, Panida and Considine, Paul and Davidson, Callum G. and Kreiner, Michaela and Halbert, Gavin and Rattray, Zahra (2024) Using asymmetric flow field-flow fractionation hyphenated with multiple detectors for the analysis of pharmaceutical bionanomaterials. In: International Flow Field Flow Fractionation Conference- IsFFF2024, 2024-06-03 - 2024-06-07, France.

Davidson, Callum G. and Punnabhum, Panida and Perrie, Yvonne and Rattray, Zahra (2024) Would you like a carrier with that? – High resolution analysis of RNA with and without a lipid nanocarrier system. In: International Flow Field Flow Fractionation Conference- IsFFF2024, 2024-06-03 - 2024-06-07, France.

Davidson, Callum and Abdulrahman, Rand and Punnabhum, Panida and Perrie, Yvonne and Rattray, Zahra (2023) Orthogonal pipelines for lipid nanoparticle evaluation. In: SciX 2023, 2023-10-08 - 2023-10-13.

Davidson, Callum G. and Abdulrahman, Rand and Cairns, Michael and Perrie, Yvonne and Rattray, Zahra (2023) Higher or lower? : the resolution of analytical pipelines for the evaluation of lipid nanoparticle critical quality attributes. In: 14th APS PharmSci International Conference 2023, 2023-09-05 - 2023-09-07, University of Reading.

Adam, Georgia and Denisov, Vladimir and Rattray, Zahra and Thomson, Adrian and Moug, Susan and Jansson, Tomas and Farrington, Susan and Moran, Carmel and Mulvana, Helen Elizabeth (2023) Characterisation of multimodal contrast agents for lymph node imaging. In: International Leeds Microbubble Symposium, 2023-07-17 - 2023-07-19, University of Leeds.

Ross, Morag and Cunningham, Margaret and Rattray, Zahra (2023) Using narrative medicine via storytelling to improve outcomes in breast cancer patients. In: IUPHAR Education Satellite Meeting, 2023-07-01 - 2023-07-02, Strathclyde Institute of Pharmacy and Biomedical Sciences.

Hill, Meghan and Cunningham, Margaret Rose and Rattray, Zahra (2023) Utilising storytelling to reveal the untold stories of breast cancer. In: IUPHAR Education Satellite Meeting, 2023-07-01 - 2023-07-02, Strathclyde Institute of Pharmacy and Biomedical Sciences.

Abdulrahman, Rand and Davidson, Callum G. and Perrie, Yvonne and Treacher, Kevin and Vasey, Catherine and Capomaccio, Robin and Rattray, Zahra (2023) Physicochemical characterisation of poly(A) lipid nanoparticles : effect of cryoprotectant and temperature storage conditions. In: European Platform for Technology Network on Nanomedicine 2023 Meeting, 2023-06-19 - 2023-06-22, University of Liverpool.

Davidson, Callum G. and Abdulrahman, Rand and Punnabhum, Panida and Perrie, Yvonne and Rattray, Zahra (2023) Go with the flow- High resolution lipid nanoparticle metrology. In: European Platform for Technology Network on Nanomedicine 2023 Meeting, 2023-06-19 - 2023-06-22, University of Liverpool.

Abdulrahman, Rand and Davidson, Callum and Perrie, Yvonne and Treacher, Kevin and Vasey, Catherine and Capomaccio, Robin and Rattray, Zahra (2023) Evaluation of the critical quality attributes of lipid nanoparticles stored under different conditions. In: UKICRS symposium 2023, 2023-06-08 - 2023-06-09, UCL.

Daramy, Karim and Punnabhum, Panida and Perrie, Yvonne and Rattray, Zahra (2023) The development of a novel pipeline for polymeric nanoparticle characterization following incubation under shear flow conditions. In: National Physical Laboratory PGI conference: Postgraduate Institute for Measurement Science Symposium 2023, 2023-06-06 - 2023-06-08, University of Strathclyde. (Unpublished)

Adam, Georgia and Densiov, Vladimir and Rattray, Zahra and Thomson, Adrian and Moug, Susan and Farrington, Susan and Jansson, Tomas and Moran, Carmel and Mulvana, Helen (2023) Optical and acoustic characterisation of multimodal contrast agents for colorectal cancer lymph node detection. In: European Molecular Imaging Meeting, 2023-03-14 - 2023-03-17.

Daramy, Karim and Perrie, Yvonne and Rattray, Zahra (2022) Understanding protein corona formation under shear flow conditions. In: JPAG Pharmaceutical Analysis Research Awards and Careers Fair 2022, 2022-11-22 - 2022-11-22, RSC.

Daramy, Karim and Minelli, Caterina and Perrie, Yvonne and Rattray, Zahra (2021) Characterization of polymeric nanoparticle-protein interactions. In: The JPAG Pharmaceutical Analysis Research Awards 2021, 2021-11-16 - 2021-11-16, Virtual.

Daramy, Karim and Minelli, Caterina and Perrie, Yvonne and Rattray, Zahra (2021) Characterization of polymeric nanoparticle-protein interactions. In: American Association of Pharmaceutical Scientists 2021, 2021-10-17 - 2021-10-20, Boston Convention & Exhibition Center.

Monograph

Armstrong, Georgina B. and Lewis, Alan and Shah, Vidhi and Taylor, Paul and Jamieson, Craig J. and Burley, Glenn A. and Lewis, Will and Rattray, Zahra (2024) A first insight into the developability of an IgG3 : a combined computational and experimental approach. Other. bioRxiv, Cold Spring Harbor, NY.

Armstrong, Georgina B and Shah, Vidhi and Sanches, Paula and Patel, Mitul and Casey, Ricky and Jamieson, Craig J and Burley, Glenn A and Lewis, William J and Rattray, Zahra (2024) Enhancing viscosity control in antibody formulations : a framework for the biophysical screening of mutations targeting solvent-accessible hydrophobic and electrostatic patches. Other. bioRxiv, Cold Spring Harbor, NY.

Cunningham, Margaret R and Rattray, Nicholas JW and McFadden, Yvonne and Berardi, Domenica and Kelly, Patricia E and Daramy, Karim and Galbraith, Allison and Lochiel, Isobel and Mills, Lorraine and Scott, Yvonne and Chalmers, Susan and Lannigan, Alison and Rattray, Zahra (2023) A roadmap for patient-public involvement and engagement (PPIE) : recounting the untold stories of breast cancer patient experiences. Other. medRxiv, Ithaca, New York.

Daramy, Karim and Punnabhum, Panida and Hussain, Muattaz Yassein Hussain and Minelli, Caterina and Pei, Yiwen and Rattray, Nicholas and Perrie, Yvonne and Rattray, Zahra (2023) Evaluating the impact of experimental shear flow parameters on nanoparticle protein corona formation. Other. ChemRxiv, Cambridge, UK.

Berardi, Domenica and Hunter, Yasmin and Van Den Driest, Lisa and Rattray, Nicholas and Rattray, Zahra and Farrell, Gillian (2022) The differential metabolic signature of breast cancer cellular response to olaparib treatment. Other. bioRxiv, Cold Spring Harbor.

van den Driest, Lisa and Johnson, Caroline H and Rattray, Nicholas JW and Rattray, Zahra (2021) Development of an accessible gene expression bioinformatics pipeline to study driver mutations of colorectal cancer. Other. medRxiv, Cold Spring Harbor.

Alnoumas, Layla and Van Den Driest, Lisa and Lannigan, Alison and Johnson, Caroline H and Rattray, Nicholas JW and Rattray, Zahra (2021) The role of KPNA2 mutations in breast cancer prognosis : a survey of publicly available databases. Other. medRxiv, New York.