Picture of fish in sea

Open Access research that uses mathematical models to solve ecological problems...

Solving a variety of ecological and biological problems is the focus of marine population modelling research conducted within the Department of Mathematics & Statistics. Here research deploys mathematical models to better understanding issues relating to fish stock management, ecosystem dynamics, ocean currents, and the effects of multispecies interactions within diverse marine ecosystems.

Research work in marine population modelling interfaces with a number of other key research specialisms, including mathematical biology, epidemiology and statistical informatics, where investigations are improving human understanding of the behaviour of infectious diseases, particularly in relation to animal infections; but also the modelling of complex biological processes such as antibiotic prodcution in actinobacteria.

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Jump to: 2014 | 2013 | 2012
Number of items: 6.

2014

Ohotski, Jan and Rosen, Hugh and Bittman, Robert and Pyne, Susan and Pyne, Nigel J (2014) Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth : the role of sphingosine 1-phosphate receptor-4. Cellular Signalling, 26 (5). pp. 1040-1047. ISSN 1873-3913

Pyne, Nigel J and Ohotski, Jan and Bittman, Robert and Pyne, Susan (2014) The role of sphingosine 1-phosphate in inflammation and cancer. Advances in Biological Regulation, 54. pp. 121-129. ISSN 2212-4934

2013

Rutherford, C and Childs, S and Ohotski, J and McGlynn, L and Riddick, M and MacFarlane, S and Tasker, D and Pyne, S and Pyne, N J and Edwards, J and Palmer, T M (2013) Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1. Cell Death and Disease, 4. e927. ISSN 2041-4889

OHOTSKI, Jan and Edwards, Joanne and Elsberger, Beatrix and Watson, Carol and Orange, Clare and Mallon, Elizabeth and Pyne, Susan and Pyne, Nigel (2013) Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer. International Journal of Cancer, 132 (3). 605–616. ISSN 0020-7136

2012

Pyne, Susan and Edwards, Joanne and OHOTSKI, Jan and Pyne, Nigel J. (2012) Sphingosine 1-phosphate receptors and sphingosine kinase 1 : novel biomarkers for clinical prognosis in breast, prostate, and hematological cancers. Frontiers in Oncology, 2. 168.

Ohotski, Jan and Long, Jaclyn and Orange, Clare and Elsberger, Beatrix and Mallon, Elizabeth and Doughty, J and Pyne, Susan and Pyne, Nigel and Edwards, Joanne (2012) Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer. British Journal of Cancer, 106 (8). pp. 1453-1459. ISSN 1532-1827

This list was generated on Sun Jul 12 09:46:33 2020 BST.