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Open Access research that better understands changing marine ecologies...

Strathprints makes available scholarly Open Access content by researchers in the Department of Mathematics & Statistics.

Mathematics & Statistics hosts the Marine Population Modelling group which is engaged in research into topics surrounding marine resource modelling and ecology. Recent work has included important developments in the population modelling of marine species.

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Number of items: 24.

McLuskey, Karen and Grewal, Jaspreet S. and Das, Debanu and Godzik, Adam and Lesley, Scott A. and Deacon, Ashley M. and Coombs, Graham H. and Elsliger, Marc-André and Wilson, Ian A. and Mottram, Jeremy C. (2016) Crystal structure and activity studies of the C11 cysteine peptidase from parabacteroides merdae in the human gut microbiome. Journal of Biological Chemistry, 291 (18). pp. 9482-9491. ISSN 1083-351X

Grewal, Jaspreet S. and McLuskey, Karen and Das, Debanu and Myburgh, Elmarie and Wilkes, Jonathan and Brown, Elaine and Lemgruber, Leandro and Gould, Matthew K. and Burchmore, Richard J. and Coombs, Graham H. and Schnaufer, Achim and Mottram, Jeremy C. (2016) PNT1 is a C11 cysteine peptidase essential for replication of the trypanosome kinetoplast. Journal of Biological Chemistry, 291 (18). pp. 9492-9500. ISSN 1083-351X

Cull, Benjamin and Godinho, Joseane Lima Prado and Rodrigues, Juliany Cola Fernandes and Frank, Benjamin and Schurigt, Uta and Williams, Roderick AM and Coombs, Graham H and Mottram, Jeremy C (2015) Glycosome turnover in Leishmania major is mediated by autophagy. Autophagy, 10 (12). pp. 2143-2157. ISSN 1554-8627

Proto, William R and Jones, N.G. and Coombs, Graham and Mottram, Jeremy (2014) Tracking autophagy during proliferation and differentiation of Trypanosoma brucei. Microbial Cell, 1 (1). pp. 9-20.

Schröder, Jörg and Noack, Sandra and Marhöfer, Richard J and Mottram, Jeremy C and Coombs, Graham H and Selzer, Paul M (2013) Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB. PLOS One, 8 (10). e77460.

Tomlins, Andrew M and Ben-Rached, Fathia and Williams, Roderick Am and Proto, William R and Coppens, Isabelle and Ruch, Ulrike and Gilberger, Tim W and Coombs, Graham H and Mottram, Jeremy C and Müller, Sylke and Langsley, Gordon (2013) Plasmodium falciparum ATG8 implicated in both autophagy and apicoplast formation. Autophagy, 9 (10). 1540 - 1552.

Sommerville, Caroline and Richardson, Julia M and Williams, Roderick A M and Mottram, Jeremy C and Roberts, Craig W and Alexander, James and Henriquez, Fiona L (2013) Biochemical and immunological characterization of Toxoplasma gondii macrophage migration inhibitory factor. Journal of Biological Chemistry, 288 (18). pp. 12733-12741. ISSN 1083-351X

Williams, Roderick A M and Mottram, Jeremy C and Coombs, Graham H (2013) Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of Leishmania major. Journal of Biological Chemistry, 288 (5). pp. 3678-3690. ISSN 1083-351X

Proto, William R and Coombs, Graham and Mottram, Jeremy (2013) Cell death in parasitic protozoa : regulated or incidental? Nature Reviews Microbiology, 11. pp. 58-66. ISSN 1740-1526

Williams, Roderick A M and Smith, Terry K and Cull, Benjamin and Mottram, Jeremy C and Coombs, Graham H (2012) ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major. PLOS Pathogens, 8 (5). e1002695.

McLuskey, Karen and Rudolf, Jana and Proto, William R and Isaacs, Neil W and Coombs, Graham H and Moss, Catherine X and Mottram, Jeremy C (2012) Crystal structure of a Trypanosoma brucei metacaspase. Proceedings of the National Academy of Sciences, 109 (19). pp. 7469-7474.

Morrison, Lesley S and Goundry, Amy and Faria, Marilia S and Tetley, Laurence and Eschenlauer, Sylvain C and Westrop, Gareth D and Dostalova, Anna and Volf, Petr and Coombs, Graham H and Lima, Ana Paula C A and Mottram, Jeremy C (2012) Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation. Cellular Microbiology.

Klionsky, Daniel J. and Abdalla, Fabio C. and Abeliovich, Hagai and Abraham, Robert T. and Acevedo-Arozena, Abraham and Adeli, Khosrow and Agnello, Maria and Al-Zeer, Munir A. and Chan, Edmond and Coombs, Graham and Menzies, Fiona Mary and Mottram, Jeremy (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8 (4). pp. 445-544. ISSN 1554-8627

Downing, Tim and Imamura, Hideo and Decuypere, Saskia and Clark, Taane G and Coombs, Graham H and Cotton, James A and Hilley, James D and de Doncker, Simonne and Maes, Ilse and Mottram, Jeremy C and Quail, Mike A and Rijal, Suman and Sanders, Mandy and Schönian, Gabriele and Stark, Olivia and Sundar, Shyam and Vanaerschot, Manu and Hertz-Fowler, Christiane and Dujardin, Jean-Claude and Berriman, Matthew (2011) Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance. Genome Research, 21 (12). pp. 2143-2156. ISSN 1088-9051

Ambit, Audrey and Woods, Kerry L. and Cull, Benjamin and Coombs, Graham H. and Mottram, Jeremy C. (2011) Morphological events during the cell cycle of Leishmania major. Eukaryotic cell, 10 (11). pp. 1429-1438.

Shweash, Muhannad and Adrienne McGachy, H and Schroeder, Juliane and Neamatallah, Thikryat and Bryant, Clare E and Millington, Owain and Mottram, Jeremy C and Alexander, James and Plevin, Robin (2011) Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression. Molecular Immunology, 48 (15-16). pp. 1800-1808.

Duszenko, Michael and Ginger, Michael L. and Brennand, Ana and Gualdrón-López, Melisa and Colombo, María Isabel and Coombs, Graham H and Coppens, Isabelle and Jayabalasingham, Bamini and Langsley, Gordon and de Castro, Solange Lisboa and Menna-Barreto, Rubem and Mottram, Jeremy C and Navarro, Miguel and Rigden, Daniel J. and Romano, Patricia S. and Stoka, Veronika and Turk, Boris and Michels, Paul A.M. (2011) Autophagy in protists. Autophagy, 7 (2). pp. 127-158.

Munday, Jane C. and McLuskey, Karen and Brown, Elaine and Coombs, Graham H and Mottram, Jeremy C (2011) Oligopeptidase B deficient mutants of Leishmania major. Molecular and Biochemical Parasitology, 175 (1). pp. 49-57. ISSN 0166-6851

Proto, William R and Castanys-Munoz, Esther and Black, Alana and Tetley, Laurence and Moss, Catherine X and Juliano, Luiz and Coombs, Graham H and Mottram, Jeremy C (2011) Trypanosoma brucei metacaspase 4 is a pseudopeptidase and a virulence factor. Journal of Biological Chemistry. ISSN 1083-351X

Millington, Owain and Myburgh, E and Mottram, Jeremy and Alexander, James (2010) Imaging of the host/parasite interplay in cutaneous leishmaniasis. Experimental Parasitology, 126 (3). pp. 310-317. ISSN 0014-4894

Eschenlauer, Sylvain C P and Faria, Marilia S and Morrison, Lesley S and Bland, Nicolas and Ribeiro-Gomes, Flavia L and DosReis, George A and Coombs, Graham H and Lima, Ana Paula C A and Mottram, Jeremy C (2008) Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major. Cellular Microbiology, 11 (1). pp. 106-120. ISSN 1462-5814

Besteiro, Sébastien and Williams, Roderick and Coombs, Graham and Mottram, Jeremy (2007) Protein turnover and differentiation in Leishmania. International Journal for Parasitology, 37 (10). 1063–1075. ISSN 0020-7519

Alphey, Magnus S. and Williams, Roderick and Mottram, Jeremy and Coombs, Graham and Hunter, William N. (2003) The crystal structure of Leishmania major 3-mercaptopyruvate sulfurtransferase : A three-domain architecture with a serine protease-like triad at the active site. Journal of Biological Chemistry, 278. pp. 48219-48227. ISSN 1083-351X

Williams, Roderick and Kelly, Sharon and Mottram, Jeremy and Coombs, Graham (2003) 3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism. Journal of Biological Chemistry, 278. pp. 1480-1486. ISSN 1083-351X

This list was generated on Mon Nov 18 15:16:44 2024 GMT.