3D printing MicroFactory for amorphous solid dispersion formulations

Prasad, Elke and Hueckman, Jill and Bordos, Ecaterina and Robertson, John and Halbert, Gavin W. (2024) 3D printing MicroFactory for amorphous solid dispersion formulations. In: CMAC Summer School 2024, 2023-07-10 - 2024-07-14.

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Abstract

This study utilised the HUB Additive-ManufacturingMicroFactory as an enabler for streamlined manufacture of Amorphous Solid Dispersion (ASD) formulation of the model compound Ritonavir with an immediate release polymer Soluplus® (BASF). The Digital Design and Manufacture of Amorphous Pharmaceuticals (DDMAP) research program identified Soluplus® as a superior polymer to form stable ASD formulation with Ritonavir. The drug release from 3D printed (3DP) Ritonavir ASD formulations with Soluplus® were compared to a commercial product (Norvir, 100mg, Abbvie Ltd).

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• Item metadata

  Item type:	Conference or Workshop Item(Poster)
  ID code:	90037
  Dates:	Date Event 14 July 2024 Published
  Subjects:	Medicine > Pharmacy and materia medica > Pharmaceutical technology Technology > Manufactures
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Technology and Innovation Centre > Continuous Manufacturing and Crystallisation (CMAC)
  Depositing user:	Pure Administrator
  Date deposited:	25 Jul 2024 12:04
  Last modified:	25 Jul 2024 12:04
  Related URLs:	Event
  URI:	https://strathprints.strath.ac.uk/id/eprint/90037