Contractile behaviour of 3T3 mouse fibroblasts in artificial skin substitutes: effect of different cell-seeding methods

Ho, G. and Grant, M.H. and Barbenel, J.C. (2002) Contractile behaviour of 3T3 mouse fibroblasts in artificial skin substitutes: effect of different cell-seeding methods. European Cells and Materials, 4 (2). pp. 55-56. ISSN 1473-2262 (http://www.ecmjournal.org/journal/supplements/vol0...)

Abstract

With the rapid development of tissue engineering and gene therapy, collagen-based biomaterials are frequently used as cell transplant devices; an example is bio-artificial skin substitutes [1-3]. In this study, we determined the effects of two different cell-seeding methods, monolayer and suspension seeding, on the rate of contraction of free-floating collagen and collagenglycosaminoglycan (GAG) gel matrices in vitro. 3T3 mouse fibroblasts were cultured in/on the matrices for up to 7 days.

ORCID iDs

Grant, M.H. ORCID: https://orcid.org/0000-0002-7712-404X

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• Item metadata

  Item type:	Article
  ID code:	6781
  Dates:	Date Event 2002 Published
  Subjects:	Technology > Engineering (General). Civil engineering (General) > Bioengineering Medicine > Medicine (General) Science > Human anatomy
  Department:	Faculty of Engineering > Bioengineering Faculty of Engineering > Electronic and Electrical Engineering
  Depositing user:	Strathprints Administrator
  Date deposited:	29 Aug 2008
  Last modified:	11 Nov 2024 08:38
  Related URLs:	http://www.ecmjournal.org/journal/supple...
  URI:	https://strathprints.strath.ac.uk/id/eprint/6781