Synthesis of functionalised 4H-quinolizin-4-ones via tandem Horner–Wadsworth–Emmons olefination/cyclisation

Muir, Calum William and Kennedy, Alan and Redmond, Joanna and Watson, Allan (2013) Synthesis of functionalised 4H-quinolizin-4-ones via tandem Horner–Wadsworth–Emmons olefination/cyclisation. Organic and Biomolecular Chemistry, 11 (20). pp. 3337-3340. ISSN 1477-0520 (https://doi.org/10.1039/c3ob40578h)

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Abstract

4H-Quinolizin-4-ones are a unique class of heterocycle with valuable physicochemical properties and which are emerging as key pharmacophores for a range of biological targets. A tandem Horner–Wadsworth–Emmons olefination/cyclisation method has been developed to allow facile access to substituted 4H-quinolizin-4-ones encoded with a range of functional groups

ORCID iDs

Muir, Calum William ORCID logoORCID: https://orcid.org/0000-0003-1032-8248, Kennedy, Alan ORCID logoORCID: https://orcid.org/0000-0003-3652-6015, Redmond, Joanna and Watson, Allan;
CORE (COnnecting REpositories)