Solid-phase synthesis of hybrid thiazolidinedione-fatty acid PPARγ ligands.

Tomkinson, Nicholas C. O. and Sefler, Andrea M. and Plunket, Kelli D. and Blanchard, Steven G. and Parks, Derek J. and Willson, Timothy M. (1997) Solid-phase synthesis of hybrid thiazolidinedione-fatty acid PPARγ ligands. Bioorganic and Medicinal Chemistry Letters, 7 (19). pp. 2491-2496. ISSN 0960-894X (https://doi.org/10.1016/S0960-894X(97)10017-8)

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Abstract

A library of thiazolidinedione-fatty acid hybrid mols. was designed to probe the relationship between natural and synthetic PPAR ligands. Solid-phase synthesis of the library led to the identification of several high affinity PPARγ ligands.

ORCID iDs

Tomkinson, Nicholas C. O. ORCID logoORCID: https://orcid.org/0000-0002-5509-0133, Sefler, Andrea M., Plunket, Kelli D., Blanchard, Steven G., Parks, Derek J. and Willson, Timothy M.;
CORE (COnnecting REpositories)