Global longitudinal strain is compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants

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Jenkinson, M. R.J. and Meek, R.M.D. and MacMillan, S. and Tate, R. and Grant, M.H. and Currie, S. (2022) Global longitudinal strain is compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants. In: Europhysiology 2022, 2022-09-16 - 2022-09-18, Tivoli Conference Centre.

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Abstract

Metal-on-metal (MoM) hip arthroplasties are known to release metal ions including cobalt into the blood stream. Elevated blood cobalt at levels over 250µg/l have been shown to be a risk factor for developing systemic complications including neurological, endocrine and cardiovascular symptoms. Published case reports document cardiomyopathy, a need for cardiac transplantation and, in some cases, death in patients with severely elevated blood cobalt. Clinical studies have found conflicting evidence of cobalt-induced cardiomyopathy in patients with MoM hips. The extent of cardiovascular injury in patients with elevated blood cobalt levels above 250µg/l has not previously been examined and is the focus of the current study.

ORCID iDs

Jenkinson, M. R.J., Meek, R.M.D., MacMillan, S. ORCID logoORCID: https://orcid.org/0000-0001-9675-3207, Tate, R., Grant, M.H. ORCID logoORCID: https://orcid.org/0000-0002-7712-404X and Currie, S. ORCID logoORCID: https://orcid.org/0000-0002-4237-4428;
CORE (COnnecting REpositories)