Injection moulding : a novel approach to the manufacture of homogenous immediate release solid oral dosage forms
Wood, Sarahjane and Halbert, Gavin and Florence, Alastair (2016) Injection moulding : a novel approach to the manufacture of homogenous immediate release solid oral dosage forms. In: 7th APS International PharmSci Conference, 2016-09-05 - 2016-09-07, University of Strathclyde.
Preview |
Text.
Filename: Wood_etal_APS2016_Injection_moulding.pdf
Accepted Author Manuscript Download (1MB)| Preview |
Abstract
The current methods of dosage form production do not control the API spatial arrangement especially when using powder blends. This research aims to use Injection Moulding as a novel alternative method taking advantage of the benefits of drug-polymer interactions. Initial studies of paracetamol PVP formulations provided units that contained crystalline paracetamol due to inefficient mixing. Methods to produce solid dispersions prior to injecting such as Hot Melt Extrusions may be necessary.
ORCID iDs
Wood, Sarahjane ORCID: https://orcid.org/0000-0002-4285-0252, Halbert, Gavin and Florence, Alastair ORCID: https://orcid.org/0000-0002-9706-8364;-
-
Item type: Conference or Workshop Item(Poster) ID code: 57644 Dates: DateEvent5 September 2016PublishedSubjects: Medicine > Therapeutics. Pharmacology Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Technology and Innovation Centre > Continuous Manufacturing and Crystallisation (CMAC)Depositing user: Pure Administrator Date deposited: 01 Sep 2016 11:52 Last modified: 22 Sep 2024 00:31 Related URLs: URI: https://strathprints.strath.ac.uk/id/eprint/57644