Development of chiral heteroleptic magnesium amides; asymmetric deprotonations mediated by six-membered metallocyclic amidomagnesium naphtholates

Tools

Carswell, Emma L. and Kerr, William J and McArthur, Duncan and Pazicky, Marek and Watson, Allan (2014) Development of chiral heteroleptic magnesium amides; asymmetric deprotonations mediated by six-membered metallocyclic amidomagnesium naphtholates. Tetrahedron, 70 (40). pp. 7344-7349. ISSN 0040-4020 (https://doi.org/10.1016/j.tet.2014.06.052)

[thumbnail of Carswell-etal2014-heteroleptic-magnesium-amides] Microsoft Word. Filename: Kerr_Aminonaphthol_Tetrahedron_Manuscript_Amend.docx
Accepted Author Manuscript
Download (328kB)

Abstract

A series of enantioenriched six-membered metallocyclic amidomagnesium naphtholates were prepared and used to probe the structure-reactivity/selectivity relationships of heteroleptic magnesium base complexes within asymmetric deprotonation reactions. An effective complex was identified and applied within enantioselective enolisation processes, delivering good levels of enantioselectivity and also revealing key structural requirements for achieving such selectivity.

ORCID iDs

Carswell, Emma L., Kerr, William J ORCID logoORCID: https://orcid.org/0000-0002-1332-785X, McArthur, Duncan, Pazicky, Marek and Watson, Allan;
  • Item type:Article
    ID code:48702
    Dates:
    Date
    Event
    7 October 2014
    Published
    18 June 2014
    Published Online
    13 June 2014
    Accepted
    Notes:. Notice: This is the author's version of a work that was accepted for publication in Tetrahedron. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Tetrahedron, Vol.70, No.40, 2014, DOI: 10.1016/j.tet.2014.06.052
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:23 Jun 2014 10:09
    Last modified:14 Dec 2024 01:15
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/48702
CORE (COnnecting REpositories)