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A new approach to oligonucleotide labelling using Diels-Alder cycloadditions and detection by SERRS

Fruk, L. and Grondin, A. and Smith, W.E. and Graham, D. (2002) A new approach to oligonucleotide labelling using Diels-Alder cycloadditions and detection by SERRS. Chemical Communications (London), 2002 (18). pp. 2100-2101. ISSN 0009-241X

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Official URL: http://dx.doi.org/10.1039/b204790j

Abstract

Diels-Alder cycloaddition has been used to add a benzotriazole azo dye to a diene tagged oligonucleotide to generate unique SERRS signals at 10 attomoles.

Item type:	Article
ID code:	1068
Keywords:	resonance raman-scattering, surface-enhanced raman, labeled dna, probes, spectroscopy, silver, acid, Chemistry, Chemistry(all)
Subjects:	Science > Chemistry
Department:	Faculty of Science > Pure and Applied Chemistry
Depositing user:	Mr Derek Boyle
Date deposited:	16 May 2006
Last modified:	03 Jan 2019 11:16
Related URLs:	http://www.rsc.org/delivery/_ArticleLink...
URI:	https://strathprints.strath.ac.uk/id/eprint/1068
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