Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine

McKeown, D. and McHugh, C.J. and McCabe, A. and Smith, W.E. and Graham, D. (2002) Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine. Heterocycles, 57 (7). pp. 1227-1230. ISSN 0385-5414

Abstract

The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.

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• Item metadata

  Item type:	Article
  ID code:	1065
  Dates:	Date Event 1 July 2002 Published
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry
  Depositing user:	Mr Derek Boyle
  Date deposited:	16 May 2006
  Last modified:	08 Apr 2024 15:24
  URI:	https://strathprints.strath.ac.uk/id/eprint/1065